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False-negative results of conventional Papanicolaou cervical cytology in women with cervical conization

Park CH

OBJECTIVE: The conventional Papanicolaou smear seems to be more accurate for detecting a high-grade squamous intraepithelial lesion (HSIL) than a low-grade squamous intraepithelial lesion (LSIL). The purpose of this study...
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Major clinical research advances in gynecologic cancer 2007

Kim K, Kim JW, Kang SB

Major clinical research advances in gynecologic cancer in 2007 are as follows. Human papillomavirus (HPV) vaccines were shown to be effective in preventing cervical intraepithelial neoplasia (CIN). In treating cervical...
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A case of massive serous ascites following radical hysterectomy with bilateral pelvic lymphadenectomy for cervical adenocarcinoma stage IB2

Hong DG, Kim BS, Lee YS, Park IS, Cho YL

Ascites following radical hysterectomy with retroperitoneal lymphadenectomy for invasive cervical cancer has been reported previously. Most of these reports described chylous ascites. The chylous ascitic fluid is milky; further, chylous...
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A case of myxoid malignant fibrous histiocytoma in the pelvic cavity

Park SH, Park CY, Lee HY, Park HW, Oh HM, Roh HS, Ha SY

Malignant fibrous histiocytoma (MFH) is the most frequent malignant soft tissue tumor in adults. A primary MFH occurs most commonly in the extremities and the trunk, but rarely in the...
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Analysis of expression of survivin, caspase 3, and p53 protein in cervical neoplasia comparing with Ki-67 index

Cha JY, Cho TI, Park TY, So JS, Choi SK, Park ES

OBJECTIVE: The aim of this study was to determine the role of survivin, caspase 3, p53 and Ki-67 expression in the carcinogenesis of cervical carcinoma and aggressiveness of cervical intraepithelial...
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Endometrial stromal sarcoma associated with extrauterine endometriosis: a case report and literature review

Park SK, Lee SJ, Kwon HS, Sohn IS, Lee JY, Kim SN, Cha YJ, Lim SD

Endometrial stromal sarcoma (ESS) that arises from extrauterine endometriosis is a rare form of malignancy. We report the case of a 37-year-old ESS patient with extrauterine endometriosis who was treated...
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Expressions of MMP-2, MMP-9, TIMP-1, and TIMP-2 as prognostic factors in endometrial cancer

Choi JR, Lee TH, Oh YL, Lee CJ, Kim WG

OBJECTIVE: Homeostasis of the extracellular matrix (ECM) is maintained by the action of a specific system of proteolytic enzymes known as matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMP)....
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Expression of MTA1 and nm23-H1 protein in ovarian carcinomas in relation to lymph node metastasis

Tong SY, Kim YY, Ki KD, Lee JM, Park YG, Lee SK

OBJECTIVE: Cancer metastasis is a complex process involving a sequential series of multi-step genetic events, which produces an imbalance between stimulatory and inhibitory genes for metastasis. Presently, we examined the...
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Induction of apoptosis by the kinase inhibitor flavopiridol in human ovarian cancer cell lines

Hur SY, Lee JM

OBJECTIVE: Flavopiridol that inhibits cyclin-dependent kinase, can cause cell cycle arrest, induce apoptosis in human tumor cell lines. In the present study, we investigated apoptotic effects of flavopiridol and the...
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Clinical analysis for the prognostic factors in patients with recurrent epithelial ovarian cancer who underwent secondary cytoreductive surgery

Kim HS, Kim TH, Chung HH, Kim JW, Park NH, Song YS, Kang SB

OBJECTIVE: To identify clinical prognostic factor improving survival of recurrent epithelial ovarian cancer (EOC) patients treated with secondary cytoreductive surgery (SCS). METHODS: The indications of SCS were as follows; 1) complete...
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Induction of apoptosis by Hibiscus protocatechuic acid in human uterine leiomyoma cells

Shon WK, Cho CH, Ramachandran S, Song DK, Shin SJ, Kwon SH, Cha SD

OBJECTIVE: Hibiscus protocatechuic acid (PCA) is a food-derived polyphenol antioxidants used as a food additive and a traditional herbal medicine. In this study, PCA was to determine its effect on...
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Effect of topical Paclitaxel using PEG/PLGA polymer on the animal model of cervical cancer

Kim CJ, Lee YS, Lee KH, Jeong B, Kim TW, Kang TH, Kim HS, Park JS

OBJECTIVE: Paclitaxel is one of the most effective antineoplastic drugs. HPV-related cervical lesions have only managed with invasive procedure. Topical drug administration with temperature sensitive copolymer gels are useful approaches...
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