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Perspectives on Adopting the Guideline for Multi-regional Clinical Trials in Korea: A Multi-stakeholder Survey

Sohn M, Song YK, Jeon AY, Oh JM, Kim IW

BACKGROUND: With the globalization of drug development, multi-regional clinical trials (MRCTs) have emerged to facilitate rapid availability of medicines to patients worldwide. The present study aimed to has explored attitudes...
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Meta-analysis on the Efficacy of Glutamate Receptor Antagonists for Acute Migraine Treatment

Kim S, Baek IH

BACKGROUND: Glutamate is implicated in the pathophysiology of migraine, a common neurological disorder. Therefore, glutamate receptor antagonists (GluRAs) have been suggested as a novel migraine treatment that are able to...
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Reviews on the Hepatotoxicity of Tyrosine Kinase Inhibitors

Han JM, Gwak HS

BACKGROUND: Small-molecule tyrosine kinase inhibitors (TKIs) have had major impacts on anticancer therapy by targeting the catalytic activities of dysregulated tyrosine kinases. TKIs have not presented traditional toxicities; however, some...
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Improvement of Waste Drug Management System by Comparing Domestic and Overseas Programs

Kim HJ, Choi YJ, Lee IH

BACKGROUND: At the end of the‘Waste Drug Disposal Project’, collection and disposal of waste drugs remain a social issue. OBJECTIVE: This study aimed to provide suggestions to improve the drug waste...
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Physical Activity and Prevalence of Rheumatoid Arthritis in Korean Adults with Prediabetes in the 2009–2013 National Health Cohort Study

Sin HY

BACKGROUND: Rheumatoid arthritis is highly prevalent in overweight patients with type 2 diabetes mellitus and can be reduced by physical activity via altered proinflammatory parameters. However, the association between the...
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Comparative Analysis of Prescription for Splitted Tablet using the HIRA-NPS (Health Insurance Review & Assessment Service-National Patient Sample)

Kwon HJ, Jang KW, Ha D

OBJECTIVE: The aim of this study was to analyze the status of split tablet prescription in South Korea. METHODS: We conducted this analysis using 2016 National Patient Sample data from the...
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Clinical Outcomes of Antiplatelets Combined with Statins in Patients with Ischemic Heart Disease

Kim C, Lee J, Park RW, Lee S

BACKGROUND: Patients with cardiovascular risks are recommended to use statins and antiplatelet agents to prevent major cerebrocardiovascular events (MACCE). Antiplatelet agents also possess anti-inflammatory and antioxidant effects, in addition to...
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Impact of Weight Change on Decline of Cognitive Function Among Korean Adults

Kim S, Shin S, Yoo H, Park GH, Lee JY, Lee JS, Lee E

BACKGROUND: In South Korea, as an aged society, an understanding of dementia and its risk factors is important from clinical and healthcare policy perspectives. Relationship between cognitive impairment and body...
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