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Independent Data Monitoring Committees: Review of Current Guidelines

Lee BR, Lee KE

BACKGROUND: There has been on increasing emphasis on the importance of monitoring the safety of participants in a clinical trial to protect patients and maintain the integrity of the trial....
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A Systematic Review on Drug Safety for Molsidomine, Nicorandil and Trimetazidine

Jeong KH, Lee E

BACKGROUND: Ischemic heart disease is the most common type of heart disease and an important cause of death in Korea. Among marketed anti-anginal medications, molsidomine, nicorandil, and trimetazidine are approved...
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Effect of Ginseng on Blood Pressure: A Systematic Review and Meta-Analysis

Ha HM, Oh DH, Chun P

OBJECTIVE: A meta-analysis was performed to determine effect of ginseng on blood pressure. METHODS: The databases of PubMed, Embase, Cochrane Library, RISS, DBpia, KISS, and Koreamed were searched for all published...
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Comparative Study of First-in-Human Dose Estimation Approaches using Pharmacometrics

Baek IH

OBJECTIVE: First-in-human dose estimation is an essential approach for successful clinical trials for drug development. In this study, we systematically compared first-in-human dose and human pharmacokinetic parameter estimation approaches. METHODS: First-in-human...
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Survey on Pharmacist's Awareness of E-commerce for Non-prescription Medicine

Park YD, Bang JS, Min YS, Sohn UD

OBJECTIVE: Online pharmacies were introduced in some countries such as United States of America or Canada. They can provide benefits to consumer because they can buy and take conveniently drugs...
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The Association between having a Usual Source of Care and Adherence to Medicines in Patients with Chronic Diseases

Jung Y, Byeon J

OBJECTIVE: This study was to explore the association between having a usual source of care and adherence to medicines in patient with chronic diseases. METHODS: The 2012 Korea Health Panel was...
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Current View of Orphan Drug Usage in Tertiary Hospital and Rare Incurable Disease Hospital

Choi KS, Jeong YM, Kim YJ, Kim YH, Gu H, Lee BK, Lee E, Rhie SJ

OBJECTIVE: Until now, there is minimal number of research for overall domestic status of orphan drug use in Korea. The purpose of this study is to identify the list of...
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Evaluation of Azithromycin Prescriptions for Pediatric Patients

Oh EK, Rhew KY

BACKGROUND: Azithromycin has broad spectrum and is effective to treat several bacterial respiratory tract infection. It is also relatively safe and tolerable to pediatric patient. Careful use of azithromycin is...
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An Analysis on Prescribing Patterns of Antidepressants and Their Associated Factors in Lung Cancer Patients

Sung KE, Jeong KH, Kim AR, Kim EY

BACKGROUND: Depression is the leading cause of lowering the quality of life of cancer patients and lung cancer is the most likely to cause depression. It is necessary to find...
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Management of Chronic Kidney Disease-Mineral Bone Disorder with Sevelamer Hcl Phosphate Binder in Korean Patients with Dialysis

Shin SW, Sin HY

BACKGROUND: Sevelamer is associated with reduced complications of chronic kidney disease-mineral bone disorder (CKD-MBD) resulted from hyperphosphatemia, which may contribute mortality, in CKD patients with dialysis. So far clinical outcomes...
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