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Hypertension and Vascular Aging

Park CG

Hypertension syndrome is a complex set of hemodynamic maladaptations that include stiff central arteries with pressure amplification, arteriolar constriction, microcirculatory rarefaction, metabolic abnormalities, cardiac hypertrophy and increased blood pressure variability....
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Unruptured Aneurysm of the Left Sinus of Valsalva Presenting as Acute Coronary Syndrome: A Case Report

Park SR, Hwang JY, Kang YR, Kang MG, Seo MG, Park SJ, Choi BR, Kwak CH

We report here on a case of a 34-year-old man with unruptured aneurysm of the left sinus of Valsalva, and he presented with acute coronary syndrome due to the putative...
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Comparison of the Long-Term Prognosis between Coronary Vasospasm and Intermediate Vasoconstriction Induced by the Administration of Acetylcholine

Shin DI, Seung KB, Kim DB, Her SH, Ham JH, Seo SM, Shin WS, Kim PJ, Chang K, Baek SH, Chung WS, Kim JH, Hong SJ, Choi KB

BACKGROUND AND OBJECTIVES: The degree of coronary vasoconstriction induced by acetylcholine administeration can vary. We compared the prognosis between coronary vasospasm and intermediate vasoconstriction, which were both induced by acetylcholine...
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The Effect of Oral Administration of Alpha Lipoic Acid and Alpha Lipoic Acid Coated Stent in Porcine In-Stent Restenosis Model

Lim SY, Bae EH, Jeong MH, Kim JH, Ahn Y, Cho JG, Park JC, Kang JC, Cho DL, Kim KS, Joo SJ

BACKGROUND AND OBJECTIVES: Alpha lipoic acid (ALA) is beneficial for improving endothelial dysfunction and preventing atherosclerosis-related diseases. We evaluated the affect of ALA on stent restenosis in a porcine model. MATERIALS...
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The Early Changing Pattern of the B-Type Natriuretic Peptide Concentration and its Significance as a Prognostic Marker after Acute Myocardial Infarction

Choe H, Yoo BS, Ryu HY, Koh SB, Chang SJ, Hwang SO, Kim JY, Lee SW, Yoon J, Choe KH

BACKGROUND AND OBJECTIVES: The BNP concentration varies considerably after the onset of AMI, and this makes it difficult to determine the right time to measure the BNP as a valid...
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Clinical and Angiographic Outcome of Sirolimus-Eluting Stent for the Treatment of Very Long Lesions

Park JS, Kim YJ, Shin DG, Shim BS, Hong GR, Bae JH, Nam CW, Hur SH, Han SW, Kim KS, Kim YN, Kim KB, Kim DI, Kim DK, Kim SM, Yang TH, Kim DS

BACKGROUND AND OBJECTIVES: Compared to bare metal stent, drug-eluting stent has improved the clinical and angiographic outcomes for de novo, simple lesions. In real world clinical practice, we often encounter...
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Plasma Osteoprotegerin Level, a New Biochemical Marker of Atherosclerosis, is Associated with Diabetes Mellitus and Age in Coronary Artery Disease

Park CS, Youn HJ, Choi YS, Lee DH, Kim JH, Oh YS, Baek SH, Chung WS, Kim JH, Choi KB, Hong SJ

BACKGROUND AND OBJECTIVES: There have been reports of an association between osteoprotegerin (OPG) and cardiovascular disease. Therefore, the aims of this study were to evaluate the association between the plasma...
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Is Systemic Inflammation Associated with Passive Smoke Exposure? A Population-Based Observational Study

Kim HY, Ihm SH, Cho EJ, Jeon DS, Baek SH, Youn HJ, Lee MY, Chung WS, Kim CJ, Seung KB, Rho TH, Kim JH, Choi KB, Hong SJ

BACKGROUND AND OBJECTIVES: Passive smoking increases the risk of cardiovascular disease, but the factors responsible for this association remain largely unknown. We sought to determine whether passive smoke exposure is...
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Curcumin Attenuates Nuclear Factor-kappaB, c-Jun N-Terminal Kinase and p38 in Tumor Necrosis Factor-alpha-Stimulated Endothelial Cells

Kim YS, Ahn Y, Hong MH, Joo SY, Kim KH, Sohn IS, Park HW, Hong YJ, Kim JH, Kim W, Jeong MH, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: Curcumin, a yellow pigment of turmeric in curry, has been reported to interfere with nuclear factor (NF)-kappaB. This study was designed to investigate the underlying pathway of...
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Influence of Vasoactive Substances on the Regulation of Cardiac ATP-Sensitive Potassium Channel Activity

Kim JH, Ju JM, Piao LH, Kim YY, Jeong HS, Park HW, Jeong DH, Lee SR, Yoon NS, Kim KH, Hong YJ, Kim JH, Kim W, Ahn YK, Jeong MH, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: It has been known that various vasoactive agents are involved in the regulation of cardiac function through the modification of the K+ channel activities, including the ATP-sensitive...
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The Prevalence and Related Risk Factors of Prehypertension among Local Residents Aged 45 or Over in Chuncheon City: The Hallym Aging Study (A Community-Based Cross-Sectional Study)

Hong KS, Jeong JY, Jang SN, Kang SH, Choi YH, Choi MG, Choi YJ, Kim DH

BACKGROUND AND OBJECTIVES: The purpose of this study is to determine the prevalence of prehypertension (preHT) among the local residents aged 45 or over, and to compare the differences in...
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