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Bosentan Attenuates Compensatory Left Ventricular Hypertrophy Induced by Aortocaval Fistula in Rats

Lee DS, Kim DK, Choi SM, Kim YK, Ko BH, Jung YW

BACKGROUND AND OBJECTIVES: Endothelin-1 (ET-1) is increased in advanced congestive heart failure and pulmonary hypertension associated with increased pulmonary blood flow. The role of ET-1 and the protective effect of...
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A Case of Acute Myocardial Infarction and Multiorgan Involvement Secondary to Rheumatoid Vasculitis

Choi HH, Jeong YD, Cho HO, Choi SJ, Jeong YS, Kim EJ, Cho KH

Rheumatoid arthritis patients have an increased risk of subclinical cardiovascular disease, and they also have a high prevalence of carotid disease and peripheral arterial disease as a form of vasculitis....
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Comparison of Isoproterenol Infusion and Nitrate Spray during Provocative Head-Up Tilt Test

Yang B, Park HW, Kim JH, Kim W, Ahn YK, Jeong MH, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: The head-up tilt test (HUT) is widely used for the diagnosis of vasovagal syncope. To improve the sensitivity of the test, provocation with isoproterenol is frequently used....
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Electrophysiological Characteristics of Arterially-Perfused Canine Pulmonary Veins: Role of the Delayed Afterdepolarization-Induced Triggered Activity

Nam GB, Choi KJ, Park DW, Kim J, Rhee KS, Kim YH

BACKGROUND AND OBJECTIVES: The mechanism responsible for the generation of ectopic beats in pulmonary veins (PVs) remains to be well defined. The present study examines the electrophysiological characteristics of the...
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The Role of P Wave from Surface Electrocardiography for the Prediction of Atrial Fibrillation after Coronary Artery Bypass Graft Surgery

Lee CK, Kim DH, Kim GC, Kwan J, Kim JT, Baek WK, Park KS, Lee WH

BACKGROUND AND OBJECTIVES: Atrial fibrillation (AF) is a common arrhythmia that develops after coronary artery bypass graft surgery (CABG), and contributes to the morbidity and prolonged length of hospital day...
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Effect of N-Acetylcysteine in Prevention of Contrast-Induced Nephropathy after Coronary Angiography

Namgung J, Doh JH, Lee SY, Huh WS, Park SW, Lee WR

BACKGROUND AND OBJECTIVES: Contrast-induced nephropathy (CIN) is associated with increased morbidity and mortality in coronary angiography. Although the mechanism is unclear, N-acetylcysteine (NAC) is known to protect against CIN. Preliminary...
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Plasma Renin Activity and Clinical Implication in Korean Hypertensive Patients

Suh SY, Park CG, Chwe UR, Kim JW, Rha SW, Seo HS, Oh DJ, Ro YM

BACKGROUND AND OBJECTIVES: Angiotension II, the active component in the renin angiotensin system, modulates blood pressure via vasoconstriction and sodium retention. In normal subjects, the active level of the RAS...
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Gene Expression Profile of Volume-Overloaded Human Ventricular Myocardium Prior to Developing Heart Failure

Yang CH, Lee SH, Park TH, Cha KS, Kim MH, Kim YD, Woo JS, Roh MS, Hwang TH

BACKGROUND AND OBJECTIVES: Left ventricle burdened by longstanding volume-overload, undergoes various structural and functional alterations. Accordingly, the expressions of multiple classes of genes are likely to be altered. However, the...
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The Relationship between the Pulse Wave Velocity(PWV) and the Left Ventricular Geometry: A Community-Based Cross-Sectional Study

Shin J, Lee J, Lim HK, Lee BH, Kim MK, Choi BY

BACKGROUND AND OBJECTIVES: Arterial compliance is a well-known factor affecting the left ventricular structure and function. Pulse wave velocity (PWV) is a reliable indicator of arterial compliance. To elucidate the...
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Primary Sirolimus-Eluting Stent Implantation for Patients with Acute ST-Segment Elevation Myocardial Infarction

Yang TH, Hong MK, Park KH, Kim MJ, Choi BR, Oh SJ, Lee BK, Kim YH, Han KH, Lee CW, Kang DH, Song JK, Kim JJ, Park SW, Park SJ

BACKGROUND AND OBJECTIVES: Sirolimus-eluting stents (SES) have been shown to significantly inhibit neointimal hyperplasia, resulting in reduced restenosis compared with bare metal stents (BMS). However, the efficacy and safety of...
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