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Bilateral Ostial Coronary Artery Lesions in a Patient with Takayasu's Arteritis

Chun KJ, Kim SI, Na MA, Choi JH

No abstract available.
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Intracoronary Radiation Therapy (IRT) for In-Stent Restenosis

Cha DH

The efficacy of beta and gamma emitters in reducing clinical and angiographic restenosis in patients with in-stent restenosis has been confirmed by a number of studies. This review is intended...
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Maternally Inherited Familial Hypertrophic Cardiomyopathy Manifested by Pregnancy Related Early Progression and Sudden Cardiac Death

Kim YH, Pak HN, Kim YH, Ro YM

Although hypertrophic cardiomyopathy (HCM) may cause heart failure, HCM and dilated cardiomyopathy (DCM) are generally recognized as separate diseases. This report describes two cases of maternally inherited familial HCM, which,...
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The Effects of Coronary Artery Remodeling on the Developments of Collateral Blood Flow in Patients with Acute Myocardial Infarction Treated with Primary Angioplasty

Park JH, Hong MK, Lee CW, Kim YH, Lee SW, He Y, Song JM, Han KH, Kang DH, Song JK, Kim JJ, Park SW, Park SJ

BACKGROUND: The relation between pressure-derived fractional collateral flow (PDCF) and coronary arterial remodeling remains uncertain in acute myocardial infarction. METHODS: We evaluated the effect of arterial remodeling on the development...
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A Clinically Silent Case of Prominent Thebesian System: Diagonal Branch of Left Anterior Descending Coronary Artery to Left Ventricular Communication

Kim EJ, Seo HS, Lee HH, Lee EM, Shin SH, Ahn JC, Park CG, Oh DJ, Ro YM

Fistulous communication from the coronary artery to the left ventricle (LV) is extremely rare and has received little attention in the literature. Moreover, a case of coronary artery fistula (CAF)...
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Closure of Coronary Artery Fistula with Covered Stent and Correction of Stenosed Left Anterior Descending Artery in the Same Procedure

He Y, Park JH, Kim YH, Lee SW, Lee JW, Hong MK, Kim JJ, Park SW, Park SJ

We report a case of closure of the coronary artery fistula with polytetrafluoroethylene (PTFE)-covered stent at the proximal left anterior descending artery along with simultaneous stenting at the stenosed middle...
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Antiplatelet Agents in High-Risk Patients with Coronary Artery Disease

Chae SC

The role of platelets is well known in the atherogenesis, acute coronary syndrome and development of complications of percutaneous coronary intervention. Until recently, aspirin was the only antiplatelet agent available...
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A Patient with Prior History of Open Heart Surgery, who Survived from a Traumatic Ventricular Free Wall and Coronary Artery Rupture, without Surgical Repair

Seo JB, Cho SH, Yoon CH, Park SJ, Chung WY, Sohn DW, Park YB, Choi YS

A case of a 23 year-old man who, thanks to his parietal pericardium, scarred by previous open heart surgery, survived traumatic ventricular free wall and coronary artery rupture, without surgical...
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Elevated Serum Homocysteine in Patients with Coronary Vasospasm

Han SW, Ryu KH, Lee Y

BACKGROUND: Homocysteine is a metabolite of methionine with atherogenic properties via endothelial dysfunction. Endothelial dysfunction is one of main pathophysiologic mechanisms of coronary vasospasm. We examined the relationship between the...
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Two Components of Voltage Dependent Outward K+ Current in Isolated Human Atrial Myocytes

Nam GB, Ho WK

BACKGROUND: The cardiac electrophysiological characteristics differ significantly among mammalian species or among various disease processes. However, difficulties in the procedures for harvesting and isolating tissue have precluded studies using human...
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Cutting Balloon Angioplasty versus Conventional Balloon Angioplasty for In-Stent Restenosis Treated by Intracoronary Radiation Therapy

Cha DH, Waksman R, Pichard AD, Satler LF, Kent KM, Lindsay J

BACKGROUND: Cutting Balloon angioplasty (CBA) may be a useful treatment modality for in-stent restenosis (ISR) as it maintains a stable position during dilatation and results in potentially less injury than...
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Adriamycin Induced Apoptosis of H9c2 Cardiomyocytes via a Caspase-Independent Pathway

Jeon MH, Youn HJ, Lee JH, Lee JH

BACKGROUND: The cardiotoxicity of adriamycin limits its clinical usefulness as a powerful drug for solid tumors and malignant hematological disease. Although the exact mechanism by which it causes cardiac damage...
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Depressed Inflammatory Response to Repeated Angioplasty in Unstable Angina Patients with an In-Stent Restenosis

Han SJ, Doo YC, Cho GY, Hong KS, Han KR, Lee NH, Oh DJ, Ryu KH, Rim CY, Lee KH, Lee Y

BACKGROUND: Inflammation plays a key role in the pathogenesis of an in-stent restenosis because it promotes neointimal proliferation. This study was performed to determine responses of the C-reactive protein (CRP)...
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The Effectiveness of Carvedilol, a New Antioxidant and Antiproliferative Beta-Blocker, on Prevention of Restenosis after Coronary Stent Implantation: a Prospective, Randomized, Multicenter Study

Cha KS, Kim MH, Kim JW, Kim DI, Kim HJ, Kim YD, Kim DS, Kim JS

BACKGROUND: Carvedilol is a direct inhibitor of vascular smooth muscle cell migration and proliferation through inhibition of mitogen-activated protein kinase activity and regulation of cell cycle progression. It produced an...
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Antioxidants Inhibit Smooth Muscle Cell Proliferation in vitro and Neointimal Hyperplasia in vivo after Carotid Artery Injury in the Rat

Kim H, Park CK, Kim KS

BACKGROUND: Smooth muscle cell proliferation and neointimal hyperplasia are major components in in-stent restenosis. In smooth muscle cells, reactive oxygen species (ROS) have been shown to mediate cell proliferation. We...
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Effect of Central Losartan on DOCA-Salt Hypertension Rats

Lee SJ, Park CG, Park JS, Kim EJ, Shin SH, Jin DG, Ahn JC, Seo HS, Oh DJ, Ro YM

BACKGROUND: The purpose of this study was to investigate whether brain AT1 receptor stimulation contributes as a hypertensive mechanism to deoxycorticosterone acetate (DOCA)-salt hypertension. METHODS: 1) Acute injection:Losartan (1 mg/4...
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Blockade of TGF-beta by Catheter-based Gene Transfer of a Soluble TGF-beta Type II Receptor Inhibits Neointima Formed after Stenting

Chung IM, Choi DH, Min PK, Chung KY

BACKGROUND: Enhanced extracellular matrix (ECM) accumulation is an important finding in coronary stent restenotic tissue, in which TGF-beta, implicated in ECM formation, is expressed abundantly. We assessed the hypothesis that...
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