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Rank-Based Nonlinear Normalization of Oligonucleotide Arrays

Park PJ, Kohane IS, Kim JH

  • KMID: 2053072
  • Genomics Inform.
  • 2003 Dec;1(2):94-100.
MOTIVATION: Many have observed a nonlinear relationship between the signal intensity and the transcript abundance in microarray data. The first step in analyzing the data is to normalize it properly,...
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Poor Correlation Between the New Statistical and the Old Empirical Algorithms for DNA Microarray Analysis

Kim JH, Kuo WP, Kong SW, Machado LO, Kohane IS

  • KMID: 2053071
  • Genomics Inform.
  • 2003 Dec;1(2):87-93.
DNA microarray is currently the most prominent tool for investigating large-scale gene expression data. Different algorithms for measuring gene expression levels from scanned images of microarray experiments may significantly impact...
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