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Novel genes in Human Asthma Based on a Mouse Model of Allergic Airway Inflammation and Human Investigations

Temesi G, Virag V, Hadadi E, Ungvari I, Fodor LE, Bikov A, Nagy A, Galffy G, Tamasi L, Horvath I, Kiss A, Hullam G, Gezsi A, Sarkozy P, Antal P, Buzas E, Szalai C

PURPOSE: Based on a previous gene expression study in a mouse model of asthma, we selected 60 candidate genes and investigated their possible roles in human asthma. METHODS: In these candidate...
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Investigation of the Possible Role of the Hippo/YAP1 Pathway in Asthma and Allergy

Fodor LE, Gézsi A, Ungvári L, Semsei AF, Gál Z, Nagy A, Gálffy G, Tamási L, Kiss A, Antal P, Szalai C

PURPOSE: Several lines of evidence indicate that the Hippo/Yes-associated protein 1 (YAP1) pathways might play a role in the pathogenesis of asthma. To investigate the possible role of the Hippo/YAP1...
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