- Regulation of Wnt signaling by protein-protein interaction and post-translational modifications
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Kikuchi A, Kishida S, Yamamoto H
- KMID: 1105271
- Exp Mol Med.
- 2006 Feb;38(1):1-10.
The Wnt signaling pathway is conserved in various species from worms to mammals, and plays important roles in cellular proliferation, differentiation, and migration. Wnt stabilizes cytoplasmic beta-catenin and then the... -
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- Clinical Characteristics of Esophageal Motility Disorders in Patients With Heartburn
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Takahashi S, Matsumura T, Kaneko T, Tokunaga M, Oura H, Ishikawa T, Nagashima A, Shiratori W, Akizue N, Ohta Y, Kikuchi A, Fujie M, Saito K, Okimoto K, Maruoka D, Nakagawa T, Arai M, Kato J, Kato N
- KMID: 2521155
- J Neurogastroenterol Motil.
- 2021 Oct;27(4):545-554.
- doi: 10.5056/jnm20131
Background/Aims Esophageal motility disorders (EMDs) contribute to the pathophysiology of gastroesophageal reflux disease. However, the causes of EMDs and their impact on gastroesophageal reflux disease-associated symptoms remain unknown. This study aims... -
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- Usefulness of waist-to-height ratio in screening incident hypertension among Japanese community-dwelling middle-aged and elderly individuals
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Kawamoto R, Kikuchi A, Akase T, Ninomiya D, Kumagi T
- KMID: 2500855
- Clin Hypertens.
- 2020 Apr;26(1):9.
- doi: 10.1186/s40885-020-00142-2
Background: The incidence of hypertension is increasing worldwide and obesity is one of the most significant risk factors. Obesity can be defined by various anthropometric indices such as body mass... -
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- Temperature-Responsive surface for novel co-culture systems of hepatocytes with endothelial cells: 2-D patterned and double layered co-cultures
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Hirose M, Yamato M, Kwon OH, Harimoto M, Kushida A, Shimizu T, Kikuchi A, Okano T
- KMID: 1114568
- Yonsei Med J.
- 2000 Dec;41(6):803-813.
- doi: 10.3349/ymj.2000.41.6.803
We have developed two novel cell co-culture system, without any on cell type combination limitation, utilizing a polymer surface which is temperature-sensitive with respect to its cell adhesion characteristics. One... -
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- Lymphadenectomy issues in endometrial cancer
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Konno Y, Asano H, Shikama A, Aoki D, Tanikawa M, Oki A, Horie K, Mitsuhashi A, Kikuchi A, Tokunaga H, Terao Y, Satoh T, Ushijima K, Ishikawa M, Yaegashi N, Watari H
- KMID: 2526370
- J Gynecol Oncol.
- 2021 Mar;32(2):e25.
- doi: 10.3802/jgo.2021.32.e25
Objectives: This review aims to introduce preoperative scoring systems to predict lymph node metastasis (LNM) and ongoing clinical trials to investigate the therapeutic role of lymphadenectomy for endometrial cancer. Methods: We... -
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