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Unveiling the genetic architecture of kidney function in the Korean population

Park S

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Does the primary cilium elongation play a role in urine concentration?

Kwon TH

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Urinary podocyte markers in diabetic kidney disease

Li C, Szeto CC

Podocytes are involved in maintaining kidney function and are a major focus of research on diabetic kidney disease (DKD). Urinary biomarkers derived from podocyte fragments and molecules have been proposed...
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School urinary screening program in Japan: history, outcomes, perspectives

Honda M, Yanagihara T, Gotoh Y

In Japan, pediatric urinary screening in schools for asymptomatic hematuria and proteinuria began in 1974 and has been very successful in detecting asymptomatic kidney diseases at an early stage. While...
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Mortality associated with the neutrophil-lymphocyte ratio in septic acute kidney injury requiring continuous renal replacement therapy

Lee J, Song J, Kim SG, Yun D, Kang MW, Kim DK, Oh KH, Joo KW, Kim YS, Han SS, Kim YC

Background: Sepsis is an important cause of acute kidney injury in intensive care unit patients, accounting for 15% to 20% of renal replacement therapy prescriptions. The neutrophil-lymphocyte ratio (NLR), a...
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Efficacy and cost-effectiveness of darbepoetin alfa once every 4 weeks versus continuous erythropoietin receptor activator once every 4 weeks for anemia correction in patients with chronic kidney disease not on dialysis

Park GN, Lee KH, Moon JE, Choi SJ, Park MY, Kim JK, Yu BC

Background: For anemia management in patients with chronic kidney disease not on dialysis, darbepoetin alfa (DA), which has a shorter half-life but is more inexpensive than continuous erythropoietin receptor activator...
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Genome-wide association study and fine-mapping on Korean biobank to discover renal trait-associated variants

Lee DJ, Moon JS, Song DK, Lee YS, Kim DS, Cho NJ, Gil HW, Lee EY, Park S

Background: Chronic kidney disease is a significant health burden worldwide, with increasing incidence. Although several genome- wide association studies (GWAS) have investigated single nucleotide polymorphisms (SNP) associated with kidney trait,...
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Triglyceride-glucose index is an independent predictor of coronary artery calcification progression in patients with chronic kidney disease

Ko YE, Kim HW, Park JT, Han SH, Kang SW, Sung S, Lee KB, Lee J, Oh KH, Yoo TH, on behalf of the KNOW-CKD investigators

Background: Coronary artery calcification (CAC) is highly prevalent in patients with chronic kidney disease (CKD) and is associated with major adverse cardiovascular events and metabolic disturbances. The triglyceride-glucose index (TyGI),...
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High water intake induces primary cilium elongation in renal tubular cells

Kong MJ, Han SJ, Seu SY, Han KH, Lipschutz JH, Park KM

Background: The primary cilium protrudes from the cell surface and functions as a mechanosensor. Recently, we found that water intake restriction shortens the primary cilia of renal tubular cells, and...
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Anti-SARS-CoV-2 spike antibody response to the third dose of BNT162b2 mRNA COVID-19 vaccine and associated factors in Japanese hemodialysis patients

Hirai K, Shimotashiro M, Okumura T, Ookawara S, Morishita Y

Background: We assessed the anti-SARS-CoV-2 spike antibody response to the third dose of BNT162b2 mRNA COVID-19 vaccine in Japanese hemodialysis patients and determined factors associated with the anti-SARS-CoV-2 spike antibody...
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Clinical relevance of blood urea nitrogen to serum albumin ratio for predicting bacteremia in very young children with febrile urinary tract infection

Hyun H, Lee Yh, Kang NY, Suh JS

Background: Urinary tract infections (UTIs) are one of the most common bacterial infections in febrile children and a common cause of hospitalization, especially in very young children. We examined the...
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Trends in clinical outcomes of older hemodialysis patients: data from the 2023 Korean Renal Data System (KORDS)

Kim H, Jeong SA, Kim KM, Hwang SD, Choi SR, Lee H, Kim JH, Kim SH, Kim TH, Koo HS, Yoon CY, Kim K, Ahn SH, Yoon HE, Kim YK, Ban TH, Hong YA

With an increasing aging population, the mean age of patients with end-stage kidney disease (ESKD) is globally increasing. However, the current clinical status of elderly patients undergoing hemodialysis (HD) is...
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Association between hearing loss and physical performance in patients on maintenance hemodialysis

Fan W, Zhong X, Wu Q, Zhang L, Yang Z, Gu Y, Guo Q, Chen X, Yu C, Zhang K, Ding W, Qi H, Zhao J, Zhang L, Zhang S, Niu J

Background: The correlation between hearing loss (HL) and physical performance in patients receiving maintenance hemodialysis (MHD) remains poorly investigated. This study explored the association between HL and physical performance in...
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