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Updates in renal pathology

Jeong HJ

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Rejection of a kidney graft revealed by positron emission tomography

Barrera-Herrera A, Gonzalez-Rojas Á, Perissinotti A, Larque AB, Cofan F, Diekmann F, Cucchiari D

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Safety and efficiency of molnupiravir for COVID-19 patients with advanced chronic kidney disease

Dufour I, Devresse A, Scohy A, Briquet C, Georgery H, Delaey P, Greef JD, Goffin E, Labriola L

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An update on renal fibrosis: from mechanisms to therapeutic strategies with a focus on extracellular vesicles

Wang C, Li SW, Zhong X, Liu BC, Lv LL

The increasing prevalence of chronic kidney disease (CKD) is a major global public health concern. Despite the complicated pathogenesis of CKD, renal fibrosis represents the most common pathological condition, comprised...
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Histologic evaluation of activity and chronicity of lupus nephritis and its clinical significance

Choi SE, Fogo AB, Lim BJ

The National Institutes of Health (NIH) lupus nephritis activity and chronicity indices, which comprise six activity scores and four chronicity scores, have a long development history. The 2018 revised International...
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Recent advances in electron microscopy for the diagnosis and research of glomerular diseases

Honda K, Takaki T, Kang D

Recent technical advances in the detection of backscattered electrons during scanning electron microscopy (SEM) have improved resolution and have provided several new technologies for research and clinical practice in kidney...
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Association between urinary chloride excretion and progression of coronary artery calcification in patients with nondialysis chronic kidney disease: results from the KNOW-CKD study

Suh SH, Oh TR, Choi HS, Kim CS, Bae EH, Ma SK, Oh KH, Yoo TH, Chae DW, Kim SW, Korean Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD) Investigators

Background: Urine chloride has recently been suggested as a biomarker of renal tubule function in patients with nondialysis chronic kidney disease (CKD), as low urinary chloride concentration is associated with...
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Serum copeptin as a predictor of risk of hyponatremia after transurethral prostatectomy

Bryc-Walczak K, Bryc W, Nowicki M

Background: Transurethral resection of the prostate gland (TURP) frequently leads to the development of dilutional hyponatremia. Copeptin has been established as a surrogate marker of vasopressin and is measured for...
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Diminazene aceturate exacerbates renal fibrosis after unilateral ureteral obstruction in female mice

Kim Y, Kim J, Han SJ

Background: Diminazene aceturate (DIZE), an angiotensin-converting enzyme 2 (ACE2) activator, exerts anti-inflammatory and antifibrotic effects in a variety of human chronic diseases. However, the role of DIZE in kidney fibrosis...
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Serum calcification propensity and its association with biochemical parameters and bone mineral density in hemodialysis patients

Kim H, Kim AJ, Ro H, Chang JH, Lee HH, Chung W, Jung JY

Background: T50 is a novel serum-based marker that assesses the propensity for calcification in serum. A shorter T50 indicates a greater propensity to calcify and has been associated with cardiovascular...
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Upregulation of NADH/NADPH oxidase 4 by angiotensin II induces podocyte apoptosis

Ha TS, Seong SB, Ha DS, Kim SJ

Background: Angiotensin II induces glomerular and podocyte injury via systemic and local vasoconstrictive or non-hemodynamic effects including oxidative stress. The release of reactive oxygen species (ROS) from podocytes may participate...
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The effects of socioeconomic status on major adverse cardiovascular events: a nationwide population-based cohort study

Bae EH, Lim SY, Yang EM, Oh TR, Choi HS, Kim CS, Ma SK, Kim B, Han KD, Kim SW

Background: Although multiple factors influence the risk of major adverse cardiovascular events (MACE), the effects of socioeconomic status on MACE in the presence and absence of renal dysfunction (RD) have...
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Evaluating the Safety and effectivenesS in adult KorEaN patients treated with Tolvaptan for management of autosomal domInAnt poLycystic kidney disease (ESSENTIAL): short-term outcomes during the titration period

Huh H, Kim YS, Chung W, Kim YL, Kim Y, Han S, Jung Y, Na KY, Lee KB, Oh YK, Park HC, Han SH, Yoo TH, Kim YH, Kim SW, Lee KW, Park HC, Kim SG, Kim H, Lee CH, Bae KT, Oh KH, Ahn C, Ryu HJ, Kim YC

Background: Tolvaptan reduces height-adjusted total kidney volume (htTKV) and renal function decline in autosomal dominant polycystic kidney disease (ADPKD). This study was aimed at investigating the efficacy and safety of...
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