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The effects of nitric oxide and 8-iso-prostaglandin F2α on chloride absorption in cortical thick ascending limb

Kwon TH

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A troubled mind troubles the kidney: a brain-to-kidney axis?

Kim KY, Kim E

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Treatment of acute tacrolimus toxicity with phenytoin after Paxlovid (nirmatrelvir/ritonavir) administration in a kidney transplant recipient

Kwon EJ, Yun GA, Park S, Kim S, Chae DW, Park HS, Lee T, Jeong JC

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Successful provision of hemodialysis to patients with confirmed COVID-19 in Korea: the role of a cooperative network between public and private medical systems

Choi JY, Lim JH, Han S, Park SC, Jung HY, Cho JH, Kim CD, Kim YL, Park SH

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Nutrition and quality of life in chronic kidney disease patients: a practical approach for salt restriction

Iseki K

The clinical practice guidelines (CPGs) for nutrition in chronic kidney disease (CKD) were updated after 20 years from the previous guidelines by the Kidney Disease Outcomes Quality Initiative (KDOQI). During...
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Advances in the management of diabetic kidney disease: beyond sodium-glucose co-transporter 2 inhibitors

Chan ATP, Tang SCW

Progress in the treatment of diabetic kidney disease (DKD) has been modest since the early trials on renin-angiotensin-aldosterone system inhibitors (RAASis). Although sodium-glucose co-transporter 2 inhibitors (SGLT2is) have revolutionized the...
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Why should we focus on high-volume hemodiafiltration?

Shin SK, Jo YI

Though noticeable technological advances related to hemodialysis (HD) have been made, unfortunately, the survival rate of dialysis patients has yet to improve significantly. However, recent research findings reveal that online...
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Clinical relevance of postoperative proteinuria for prediction of early renal outcomes after kidney transplantation

Jun J, Park K, Lee HS, Lee KW, Lee JE, Park JB, Kim K, Huh W, Kim YG, Kim DJ, Jang HR

Background: Proteinuria is associated with poor allograft and patient survival in kidney transplant recipients. However, the clinical relevance of spot urine protein-to-creatinine ratio (PCR) or albumin-to-creatinine ratio (ACR) as predictors...
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Associations among Alzheimer disease, depressive disorder, and risk of end-stage kidney disease in elderly people

Kang SC, Koh HB, Kim HW, Joo YS, Han SH, Yoo TH, Kang SW, Park JT

Background: Alzheimer disease (AD) and depressive disorder (DD) are prevalent among elderly end-stage kidney disease (ESKD) patients. However, whether preexisting mental health disorders increase the risk of ESKD is not...
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Healthy aging and chronic kidney disease

Merchant RA, Vathsala A

The world population is aging and the prevalence of noncommunicable diseases such as diabetes, hypertension, and chronic kidney disease (CKD) will increase significantly. With advances in medical treatment and public...
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Identification of osteopontin as a urinary biomarker for autosomal dominant polycystic kidney disease progression

Kim H, Sung J, Bae JY, Lee P, Oh YK, Kim H

Background: Autosomal dominant polycystic kidney disease (ADPKD), one of the most common human monogenic diseases, is characterized by the presence of numerous fluid-filled renal cysts and is a leading cause...
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Hospital mortality and prognostic factors in critically ill patients with acute kidney injury and cancer undergoing continuous renal replacement therapy

Kim DW, Jang GS, Jung KS, Jung HJ, Kim HJ, Rhee H, Seong EY, Song SH

Background: Whether continuous renal replacement therapy (CRRT) should be applied to critically ill patients with both acute kidney injury (AKI) and cancer remains controversial because of poor expected outcomes. The...
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Association of sarcopenia and its components with clinical outcomes in patients undergoing peritoneal dialysis

Kang SH, Kim AY, Do JY

Background: Further studies are needed to identify whether muscle mass, muscle strength, or sarcopenia is the best indicator of survival in patients undergoing peritoneal dialysis (PD). We aimed to compare...
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Nitric oxide-inhibited chloride transport in cortical thick ascending limbs is reversed by 8-iso-prostaglandin-F2α

Cabral PD, Silva GB, Baigorria ST, Juncos LI, Ajayi EIO, García NH

Background: Sodium chloride (NaCl) reabsorption in the cortical thick ascending limb (cTAL) is regulated by opposing effects. Nitric oxide (NO) inhibits NaCl reabsorption while 8-iso-prostaglandin-F2α (8-iso-PGF2α) stimulates it. Their interaction...
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