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Analyzing the Association of Visceral Adipose Tissue Growth Differentiation Factor-15 and MicroRNA in Type 2 Diabetes Mellitus

Roy D, Purohit P, Khokhar M, Modi A, Shukla RKG, Chaudhary R, Sankanagoudar S, Sharma P

Background: Growth differentiation factor-15 (GDF-15) is involved in insulin resistance and diabetes. In this study, we determine the associations of GDF-15 with miR-181b-5p, miR-330-3p, mothers against decapentaplegic homolog 7 (SMAD7),...
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Leptin DNA Methylation and Its Association with Metabolic Risk Factors in a Northwest Indian Obese Population

S, Modi A, Khokhar M, Sharma P, Joshi R, Mishra SS, Bharshankar RN, Tiwari S, Singh PK, Bhosale VV, Singh Negi MP

Background: It is well established that obesity is a major health risk in diabetes and associated diseases. Epigenetic changes, specially DNA methylation, play an important role in regulation of adipokines....
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