- Effect of Extracellular Signal-Regulated Kinase Inhibition on Oxysterol 7-Ketocholesterol-Induced Apoptosis
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Hwang JY, Lee SW, Han JH, Kim DE, Lee CS
- KMID: 1966474
- J Korean Neurol Assoc.
- 2011 Nov;29(4):317-325.
BACKGROUND: Defects in mitochondrial function have been shown to participate in the induction of neuronal cell injury. The extracellular-signal-regulated kinase (ERK) signaling pathway plays a crucial role in almost all... -
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- Prostaglandin E2 Attenuates 7-Ketocholesterol Toxicity by Suppressing Changes in Mitochondria-Associated Cell Death Process
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Ahn KM, Lee SY, Han JH, Kim DE, Lee CS
- KMID: 1813208
- J Korean Neurol Assoc.
- 2009 Aug;27(3):243-250.
BACKGROUND: It has been shown that defects in mitochondrial function are involved in the induction of neuronal cell injury. Prostanoids such as prostaglandin E2 (PGE2) are thought to play an... -
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- Inhibitory Effect of Tyrphostin AG126 on Brain Synaptosomal Dysfunction Induced by Cholesterol Oxidation Products
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Hong KM, Han JH, Kim DE, Song JH, Lee CS
- KMID: 2185067
- J Korean Neurol Assoc.
- 2008 Aug;26(3):231-238.
BACKGROUND: Formation of cholesterol oxidation products is a suggested mechanism of neurodegenerative disorders. Neuronal cell death is mediated by an increased release of excitotoxic glutamate from the presynaptic nerve endings.... -
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