- 12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity
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Lee JW, Ryu HC, Ng YC, Kim C, Wei JD, Sabaratnam V, Kim JH
- KMID: 1383800
- Exp Mol Med.
- 2012 Jun;44(6):378-386.
12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. Despite the high level of 12-HHT present in tissues and bodily fluids,... -
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