- Ceramide Synthase 6 Mediates TripleNegative Breast Cancer Response to Chemotherapy Through RhoA- and EGFR-Mediated Signaling Pathways
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Chen H, He B, Ke F
- KMID: 2537648
- J Breast Cancer.
- 2022 Dec;25(6):500-512.
- doi: 10.4048/jbc.2022.25.e47
Purpose: Limited treatment options and lack of treatment sensitivity biomarkers make the clinical management of triple-negative breast cancer (TNBC) challenging. Ceramide synthase 6 (CERS6) generates ceramides, which are key intermediates... -
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