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A potent multivalent vaccine for modulation of immune system in atherosclerosis: an in silico approach

Karkhah A, Amani J

PURPOSE: Atherosclerosis is classically defined as an immune-mediated disease characterized by accumulation of low-density lipoprotein cholesterol over intima in medium sized and large arteries. Recent studies have demonstrated that both...
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Elevated expression of DNMT1 is associated with increased expansion and proliferation of hematopoietic stem cells co-cultured with human MSCs

Ahmadnejad M, Amirizadeh N, Mehrasa R, Karkhah A, Nikougoftar M, Oodi A

BACKGROUND: Mesenchymal stem cells (MSCs) play an important role in hematopoietic stem cell (HSC) maintenance, proliferation, and apoptosis. DNA methyltransferase 1 (DNMT1) is considered an essential factor in the maintenance...
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