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Classification and Management Algorithm for Postoperative Wound Complications Following Transforaminal Lumbar Interbody Fusion

Kanna RM, Renjith KR, Shetty AP, Rajasekaran S

Study Design: Retrospective study. Purpose: Postoperative wound complications occurring after transforaminal lumbar interbody fusion (TLIF) are unique, as they can involve different tissue zones (subcutaneous, subfascial, osseous, peri-implant, and disc). Overview...
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Validation Study of Rajasekaran’s Kyphosis Classification System: Do We Clearly Understand Single- and Two-Column Deficiencies?

Shetty AP, Rajavelu R, Viswanathan VK, Watanabe K, Chhabra HS, Kanna RM, Cheung JPY, Hai Y, Kwan MK, Wong CC, Liu G, Basu S, Nene A, Naresh-Babu J, Garg B

Study Design: Multicenter validation study. Purpose: To evaluate the inter-rater reliability of Rajasekaran’s kyphosis classification through a multicenter validation study. Overview of Literature: The classification of kyphosis, developed by Rajasekaran, incorporates factors...
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Motion-Preserving Navigated Primary Internal Fixation of Unstable C1 Fractures

Rajasekaran S, Soundararajan DCR, Shetty AP, Kanna RM

Study Design: Prospective observational study. Purpose: To assess the safety, efficacy, and benefits of computed tomography (CT)-guided C1 fracture fixation. Overview of Literature: The surgical management of unstable C1 injuries by occipitocervical...
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Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc

Rajasekaran S, Soundararajan DCR, Tangavel C, K. S. SVA, Nayagam SM, Matchado MS, Muthurajan R, Shetty AP, Kanna RM, Dharmalingam K

Study Design: Profiling proteins expressed in the nucleus pulposus of fetal intervertebral disc (IVD). Purpose: To evaluate the molecular complexity of fetal IVDs not exposed to mechanical, traumatic, inflammatory, or infective...
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Proteomic Signatures of Healthy Intervertebral Discs From Organ Donors: A Comparison With Previous Studies on Discs From Scoliosis, Animals, and Trauma

Rajasekaran S, Tangavel C, Soundararajan DCR, Nayagam SM, Matchado MS, Muthurajan R, Anand KSV, Rajendran S, Shetty AP, Kanna RM, Kuppamuthu D

Objective: To catalog and characterize the proteome of normal human intervertebral disc (IVD). Methods: Nine magnetic resonance imaging (MRI) normal IVDs were harvested from 9 different brain dead yet alive voluntary...
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Unplanned Readmissions after Spine Surgery: A Single-Center Prospective Analysis of a 90-Day Model in 2,860 Cases

Avinash M, Renjith KR, Shetty AP, Sharma V, Kanna RM, Rajasekaran S

Study Design: Prospective study. Purpose: During the last decades, an emergence of unplanned readmissions has been shown to be a useful tool to gage the healthcare quality and hospital performance. Previous...
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Does Sarcopenia Increase the Risk for Fresh Vertebral Fragility Fractures?: A Case-Control Study

Anand A, Shetty AP, Renjith KR, K. S. SVA, Kanna RM, Rajasekaran S

Study Design: Case-control study. Purpose: Sarcopenia is an age associated condition characterized by decrease in muscle mass, strength, and physical performance. We aimed to investigate whether sarcopenia increased the risk of...
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Congenital Osseous Anomalies of the Cervical Spine: Occurrence, Morphological Characteristics, Embryological Basis and Clinical Significance: A Computed Tomography Based Study

Ankith N, Avinash M, Srivijayanand K, Shetty AP, Kanna RM, Rajasekaran S

STUDY DESIGN: Observational retrospective computed tomography (CT) based study. PURPOSE: To analyze the congenital anomalies of the cervical spine, their morphological variations and their clinical significance. OVERVIEW OF LITERATURE: Studies published to...
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The Effectiveness of Noninvasive Positive Pressure Ventilation in Subarachnoid Pleural Fistula: A Case Report and Literature Review

Soundararajan DCR, Shetty AP, Kanna RM, Rajasekaran S

Subarachnoid pleural fistula (SPF) is an aberrant communication between the pleural cavity and subarachnoid space, resulting in uncontrolled cerebrospinal fluid drainage. The negative pressure of the pleural cavity creates a...
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Factors Influencing Postoperative Urinary Retention Following Elective Posterior Lumbar Spine Surgery: A Prospective Study

Aiyer SN, Kumar A, Shetty AP, Kanna RM, Rajasekaran S

STUDY DESIGN: Prospective observational study. PURPOSE: To determine the incidence of postoperative urinary retention (POUR) in patients undergoing elective posterior lumbar spine surgery and identify the risk factors associated with the...
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Reciprocal Changes in Sagittal Alignment in Adolescent Idiopathic Scoliosis Patients Following Strategic Pedicle Screw Fixation

Dumpa SR, Shetty AP, Aiyer SN, Kanna RM, Rajasekaran S

STUDY DESIGN: Retrospective observational study. PURPOSE: To analyze the effect of low-density (LD) strategic pedicle screw fixation on the correction of coronal and sagittal parameters in adolescent idiopathic scoliosis (AIS) patients. OVERVIEW...
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Morphometric Evaluation of Occipital Condyles: Defining Optimal Trajectories and Safe Screw Lengths for Occipital Condyle-Based Occipitocervical Fixation in Indian Population

Bosco A, Venugopal , Shetty AP, Shanmuganathan R, Kanna RM

STUDY DESIGN: Computed tomographic (CT) morphometric analysis. PURPOSE: To assess the feasibility and safety of occipital condyle (OC)-based occipitocervical fixation (OCF) in Indians and to define anatomical zones and screw lengths...
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Analysis of Spinopelvic Parameters with L5 as the New Sacrum after Fusion in High-Grade Spondylolisthesis: A Possible Explanation for Satisfactory Results with In-Situ Fusion

Rajasekaran S, Das G, Aiyer SN, Kanna RM, Shetty AP

STUDY DESIGN: Retrospective case series. PURPOSE: To correlate functional outcomes with spinopelvic parameters in patients with high-grade spondylolisthesis (HGS) treated with instrumented in-situ surgery or reduction and fusion. OVERVIEW OF LITERATURE: Satisfactory...
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Prevalence, Patterns, and Genetic Association Analysis of Modic Vertebral Endplate Changes

Kanna RM, Shanmuganathan R, Rajagopalan VR, Natesan S, Muthuraja , Cheung KM, Chan D, Kao PY, Yee A, Shetty AP

STUDY DESIGN: A prospective genetic association study. PURPOSE: The etiology of Modic changes (MCs) is unclear. Recently, the role of genetic factors in the etiology of MCs has been evaluated. However,...
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Circumferential Fusion through All-Posterior Approach in Andersson Lesion

Rajoli SR, Kanna RM, Aiyer SN, Shetty AP, Rajasekaran S

STUDY DESIGN: Retrospective case series. PURPOSE: To assess safety and efficacy of single stage, posterior stabilisation and anterior cage reconstruction through the transforaminal or lateral extra-cavitary route for Andersson lesions. OVERVIEW OF...
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