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Response to: A Randomized Control Trial Comparing Local Autografts and Allografts in Single Level Anterior Cervical Discectomy and Fusion Using a Stand-Alone Cage

Kanna RM, Perambuduri AS, Shetty AP, Rajasekaran S

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The Effectiveness of Noninvasive Positive Pressure Ventilation in Subarachnoid Pleural Fistula: A Case Report and Literature Review

Soundararajan DCR, Shetty AP, Kanna RM, Rajasekaran S

Subarachnoid pleural fistula (SPF) is an aberrant communication between the pleural cavity and subarachnoid space, resulting in uncontrolled cerebrospinal fluid drainage. The negative pressure of the pleural cavity creates a...
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Impact of Acute Lumbar Disk Herniation on Sexual Function in Male Patients

Panneerselvam K, Kanna RM, Shetty AP, Rajasekaran S

Study Design: Prospective observational study. Purpose: In this study, we determined the effects of lumbar disk herniation (LDH) on male sexual activity and whether surgical intervention improved any related sexual dysfunction. Overview...
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Does Sarcopenia Increase the Risk for Fresh Vertebral Fragility Fractures?: A Case-Control Study

Anand A, Shetty AP, Renjith KR, K. S. SVA, Kanna RM, Rajasekaran S

Study Design: Case-control study. Purpose: Sarcopenia is an age associated condition characterized by decrease in muscle mass, strength, and physical performance. We aimed to investigate whether sarcopenia increased the risk of...
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Patterns of Traumatic Spinal Injuries in the Developing World: A Five-Year Longitudinal Review

Kanna RM, Peddireddy S, Shetty AP, Rajasekaran S

Study Design: Retrospective review. Purpose: A 5-year longitudinal study documenting and comparing patterns of traumatic spinal injuries (TSIs) observed in developing countries. Overview of Literature: Current knowledge of the patterns and epidemiology...
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Classification and Management Algorithm for Postoperative Wound Complications Following Transforaminal Lumbar Interbody Fusion

Kanna RM, Renjith KR, Shetty AP, Rajasekaran S

Study Design: Retrospective study. Purpose: Postoperative wound complications occurring after transforaminal lumbar interbody fusion (TLIF) are unique, as they can involve different tissue zones (subcutaneous, subfascial, osseous, peri-implant, and disc). Overview...
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Posterior Stabilization of Unstable Sacral Fractures: A Single-Center Experience of Percutaneous Sacroiliac Screw and Lumbopelvic Fixation in 67 Cases

Shetty AP, Renjith KR, Perumal R, Anand SV, Kanna RM, Rajasekaran S

Study Design: This is a retrospective study. Purpose: Recent advances in intraoperative imaging and closed reduction techniques have led to a shifting trend toward surgical management in every unstable sacral fracture....
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Analysis of Postoperative Clinical Outcomes in Cervical Myelopathy due to Ossification of Posterior Longitudinal Ligament Involving C2

Shetty AP, Singh NA, Kalanjiyam GP, Meena J, Rajasekaran S, Kanna RM

Study Design: Retrospective study. Purpose: To investigate the radiological phenotype, patient and surgery-related risk factors influencing postoperative clinical outcome for cervical myelopathy caused by ossification of the posterior longitudinal ligament involving...
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In Vertebral Hemangiomas with Neurological Deficit, Is a Less Extensive Approach Adequate

K. GP, Shetty AP, K. S. SVA, Kavishwar R, Kanna RM, Rajasekaran S

Study Design: This was a retrospective study. Purpose: To analyze the surgical and neurological outcomes following surgical decompression in patients with aggressive vertebral hemangioma (AVH) presenting with neurological deficit and to...
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Congenital Osseous Anomalies of the Cervical Spine: Occurrence, Morphological Characteristics, Embryological Basis and Clinical Significance: A Computed Tomography Based Study

Ankith N, Avinash M, Srivijayanand K, Shetty AP, Kanna RM, Rajasekaran S

STUDY DESIGN: Observational retrospective computed tomography (CT) based study. PURPOSE: To analyze the congenital anomalies of the cervical spine, their morphological variations and their clinical significance. OVERVIEW OF LITERATURE: Studies published to...
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A Randomized Control Trial Comparing Local Autografts and Allografts in Single Level Anterior Cervical Discectomy and Fusion Using a StandAlone Cage

Kanna RM, Perambuduri AS, Shetty AP, Rajasekaran S

Study Design: Randomized controlled trial. Purpose: To compare the functional and radiological outcomes of anterior cervical discectomy and fusion (ACDF) using local graft and allograft Overview of Literature: The choice of bone...
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Motion-Preserving Navigated Primary Internal Fixation of Unstable C1 Fractures

Rajasekaran S, Soundararajan DCR, Shetty AP, Kanna RM

Study Design: Prospective observational study. Purpose: To assess the safety, efficacy, and benefits of computed tomography (CT)-guided C1 fracture fixation. Overview of Literature: The surgical management of unstable C1 injuries by occipitocervical...
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Novel Biomarkers of Health and Degeneration in Human Intervertebral Discs: In-depth Proteomic Analysis of Collagen Framework of Fetal, Healthy, Scoliotic, Degenerate, and Herniated Discs

Rajasekaran S, Soundararajan DCR, Nayagam SM, Tangavel C, Raveendran M, K S SVA, Shetty AP, Kanna RM

Study Design: Profiling proteins expressed in the nucleus pulposus (NP) of intervertebral discs (IVDs) in five different biological states. Purpose: To evaluate the molecular complexity of the collagen (COL) framework and...
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Type I Arnold Chiari Malformation with Syringomyelia and Scoliosis: Radiological Correlations between Tonsillar Descent, Syrinx Morphology and Curve Characteristics: A Retrospective Study

Shanmugasundaram S, Viswanathan VK, Shetty AP, Rai N, Hajare S, Kanna RM, Rajasekaran S

Study Design: Retrospective cohort. Purpose: The current study was planned to evaluate deformity characteristics, assess relationship between morphology of syrinx/Arnold Chiari malformation (ACM) and deformity, analyze effect of posterior fossa decompression...
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Functional and Radiological Outcomes of All-Posterior Surgical Correction of Dystrophic Curves in Patients with Neurofibromatosis Type 1

Shetty AP, Meena J, Murugan C, Milton R, Kanna RM, Rajasekaran S

Study Design: A retrospective cohort study. Purpose: To determine outcomes following all-posterior surgery using computed tomography navigation, hybrid stabilization, and multiple anchor point techniques in patients with neurofibromatosis type 1 (NF-1)...
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Proteomic Signatures of Healthy Intervertebral Discs From Organ Donors: A Comparison With Previous Studies on Discs From Scoliosis, Animals, and Trauma

Rajasekaran S, Tangavel C, Soundararajan DCR, Nayagam SM, Matchado MS, Muthurajan R, Anand KSV, Rajendran S, Shetty AP, Kanna RM, Kuppamuthu D

Objective: To catalog and characterize the proteome of normal human intervertebral disc (IVD). Methods: Nine magnetic resonance imaging (MRI) normal IVDs were harvested from 9 different brain dead yet alive voluntary...
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Unplanned Readmissions after Spine Surgery: A Single-Center Prospective Analysis of a 90-Day Model in 2,860 Cases

Avinash M, Renjith KR, Shetty AP, Sharma V, Kanna RM, Rajasekaran S

Study Design: Prospective study. Purpose: During the last decades, an emergence of unplanned readmissions has been shown to be a useful tool to gage the healthcare quality and hospital performance. Previous...
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Factors Influencing Postoperative Urinary Retention Following Elective Posterior Lumbar Spine Surgery: A Prospective Study

Aiyer SN, Kumar A, Shetty AP, Kanna RM, Rajasekaran S

STUDY DESIGN: Prospective observational study. PURPOSE: To determine the incidence of postoperative urinary retention (POUR) in patients undergoing elective posterior lumbar spine surgery and identify the risk factors associated with the...
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Does Magnetic Resonance Imaging Predict Neurological Deficit in Patients with Traumatic Lower Lumbar Fractures?

Ramachandran K, Iyer RD, Suresh PB, Shetty AP, Thippeswamy PB, Kanna RM, Rajasekaran S

Study Design: A retrospective cohort study. Purpose: This study aimed to understand the role of magnetic resonance imaging (MRI) in predicting neurological deficits in traumatic lower lumbar fractures (LLFs; L3–L5). Overview of...
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Analysis of Spinopelvic Parameters with L5 as the New Sacrum after Fusion in High-Grade Spondylolisthesis: A Possible Explanation for Satisfactory Results with In-Situ Fusion

Rajasekaran S, Das G, Aiyer SN, Kanna RM, Shetty AP

STUDY DESIGN: Retrospective case series. PURPOSE: To correlate functional outcomes with spinopelvic parameters in patients with high-grade spondylolisthesis (HGS) treated with instrumented in-situ surgery or reduction and fusion. OVERVIEW OF LITERATURE: Satisfactory...
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