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Aging effects on the diurnal patterns of gut microbial composition in male and female mice

Kim HJ, Moon CM, Kang JL, Park EM

Composition of the gut microbiota changes with aging and plays an important role in age-associated disease such as metabolic syndrome, cancer, and neurodegeneration. The gut microbiota composition oscillates through the...
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Caveolin-1 is involved in reactive oxygen species-induced SHP-2 activation in astrocytes

Yun JH, Park SJ, Jo A, Kang JL, Jou I, Park JS, Choi YH

Recent evidence supports a neuroprotective role of Src homology 2-containing protein tyrosine phosphatase 2 (SHP-2) against ischemic brain injury. However, the molecular mechanisms of SHP-2 activation and those governing how...
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