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Production of Recombinant Retroviruses Encoding Human Flt3 Ligand and IL-6 and Establishment of Genetically Modified OP9 Mouse Stromal Cells

Kang HB, Kim YE, Kang HJ, Lee AR, Seok DE, Lee Y

Flt3 Ligand (FL) and IL-6 are multifunctional cytokines implicated in normal hematopoiesis and ex vivo expansion of hematopoietic stem cells. Retroviral vectors are useful for stable expression of genes in...
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Characterization of the Monoclonal Antibody Specific to Human S100A6 Protein

Kim JW, Yoon SY, Joo JH, Kang HB, Lee YH, Choe YK, Choe IS

BACKGROUND: S100A6 is a calcium-binding protein overexpressed in several tumor cell lines including melanoma with high metastatic activity and involved in various cellular processes such as cell division and differentiation....
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1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression

Yoon SY, Kang HB, Ko YE, Shin SH, Kim YJ, Sohn KY, Han YH, Chong S, Kim JW

Controlling balance between T-helper type 1 (Th1) and T-helper type 2 (Th2) plays a pivotal role in maintaining the biological rhythm of Th1/Th2 and circumventing diseases caused by Th1/Th2 imbalance....
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Analysis of Drug Utilization for Patients with Ankylosing Spondylitis

Kang HB, Je NK

BACKGROUND & OBJECT: Ankylosing spondylitis (AS) is a chronic inflammatory disease that causes ankylosis and deformation of axial joints. Since current medicine cannot cure the disease yet, alleviating pain and...
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Changes in Matrix Metalloproteinase and Tissue Inhibitors of Metalloproteinase in Patients with Rotator Cuff Tears

Kwon OS, Kim YY, Ha JY, Kang HB

  • KMID: 2049428
  • Clin Should Elbow.
  • 2014 Jun;17(2):64-67.
BACKGROUND: The purpose of this study was to determine whether in patients with rotator cuff tears a correlation exists between molecular changes and clinical parameters such as age, duration of...
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Characterization of a Monoclonal Antibody Specific to Human Siah-1 Interacting Protein

Yoon SY, Joo JH, Kim JH, Kang HB, Kim JS, Lee Y, Kwon DH, Kim CN, Choe IS, Kim JW

BACKGROUND: A human orthologue of mouse S100A6-binding protein (CacyBP), Siah- 1-interacting protein (SIP) had been shown to be a component of novel ubiquitinylation pathway regulating beta-catenin degradation. The role of...
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The functional role of the CARM1-SNF5 complex and its associated HMT activity in transcriptional activation by thyroid hormone receptor

Choi HK, Choi KC, Oh SY, Kang HB, Lee YH, Haam S, Ahn YH, Kim KS, Kim K, Yoon HG

  • KMID: 756078
  • Exp Mol Med.
  • 2007 Aug;39(4):544-555.
We have investigated the function and mechanisms of the CARM1-SNF5 complex in T3-dependent transcriptional activation. Using specific small interfering RNAs (siRNA) to knock down coactivators in HeLa alpha2 cells, we...
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