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Ramelteon for Delayed Sleep-wake Phase Disorder: A Case Report

Takeshima M, Shimizu T, Ishikawa H, Kanbayashi T

Recently developed melatonin receptor agonists are expected to be effective for delayed sleep-wake phase disorder (DSWPD). To date, however, no study has described the effect of melatonin receptor agonists on...
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Late-Onset Narcolepsy with Cataplexy Unresponsive to Intravenous High-Dose Immunoglobulin Treatment

Cho JW, Jung NY, Bae JW, Kim DJ, Lee JH, Kanbayashi T

  • KMID: 2343436
  • J Korean Neurol Assoc.
  • 2012 Feb;30(1):57-59.
Narcolepsy with cataplexy (NC) is associated with hypocretin deficiency, and is thought to be an autoimmunity condition. The mean age at onset is estimated to be in the early 20s....
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Relationship between Clozapine-Induced Electroencephalogram Abnormalities and Serum Concentration of Clozapine in Japanese Patients with Treatment-Resistant Schizophrenia

Kikuchi YS, Kanbayashi T, Shimizu T

OBJECTIVE: The objective of this study was to investigate the relationship between the serum concentration of clozapine (C-CLZ), N-desmethylclozapine (N-CLZ) and the daily dose of CLZ (D-CLZ), and the relationships...
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Successful Management of Clozapine-induced Akathisia with Gabapentin Enacarbil: A Case Report

Takeshima , Ishikawa H, Kikuchi Y, Kanbayashi T, Shimizu T

The management of clozapine (CLZ)-induced adverse events affects patient prognoses. Akathisia is a relatively rare adverse event related to CLZ administration and thus the management of this syndrome is not...
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