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Vascular Aspects of Bronchopulmonary Dysplasia

Cho SJ

Bronchopulmonary dysplasia (BPD) is characterized by arrest of vascular and alveolar development in premature infants. Recent advances in neonatology have increased the survival of immature babies. Consequently, the prevalence of...
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Noonan Syndrome Confirmed to KRAS Gene Mutation: A Case of KRAS Gene Mutation

Kim SW, Park SE, Jeong IH, Yoon JW, Lee CA, Jeon JH

Noonan syndrome is an autosomal dominant disorder characterized by typical facial features, congenital heart disease, and short stature. Diagnosis is difficult only with clinical symptoms and it is recently confirmed...
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Iatrogenic Esophageal Perforation: An Occurrence from Feeding Tube Placement in a Premature Infant with a Pneumothorax

Jang YU, Jang WJ, Cho HJ, Choi DY, Shim SY, Son DW

Spontaneous neonatal esophageal perforation (EP) is a rare condition. However, iatrogenic EP due to a feeding tube is not uncommon, particularly in premature infants. Iatrogenic EP can result in serious...
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A Case of Urinary Ascites with Urinoma Secondary to Ureteropelvic Junction Obstruction in a Neonate

Choi MS, Kim EY, Park SK, Kim DH, Jung HJ

Spontaneous intraperitoneal extravasation of urine is rare. Perirenal urinoma may develop when obstruction to urinary flow creates sufficient back pressure to produce extravasation of urine. Urinary ascites most commonly indicate...
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Analysis of Infant Mortality Rate in Korea Concerning According to Birth Weight and Gestational Age from 2005 to 2009

Cho MJ, Ko JH, Chung SH, Choi YS, Hahn WH, Chang JY, Bae CW

PURPOSE: Recently in Korea, there have been significant improvements in neonatal mortality rate (NMR) and infant mortality rate (IMR). This study aimed to investigate the proportion of the NMR among...
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Alveolar Aspect of Bronchopulmonary Dysplasia

Choi CW

The pathologic hallmark of new bronchopulmonary dysplasia (BPD) is an arrest in alveolarization and vascular development. Alveoli are the fully mature gas-exchange units and alveolarization denotes the process through which...
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A Case of Neonatal Lupus Erythematosus and Retrospectively Diagnosed with Asymtomatic Maternal Lupus Erythematosus

Han JY, Yoon JM, Kim JB, Lim JW, Lee YH, Ko KO

Neonatal lupus erythematosus (NLE) is a rare disease characterized by typical clinical features and the transplacental passage of maternal autoantibodies, particularly anti-SSA/Ro. The major clinical manifestations are cutaneous lupus lesions,...
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Identification of Characteristics and Risk Factors Associated with Mortality in Hydrops Fetalis

Ko H, Lee BS, Kim KS, Won HS, Lee PR, Shim JY, Kim A, Kim AR

PURPOSE: The objectives were to identify the characteristics of neonates with hydrops fetalis, and to identify the risk factors associated with mortality. METHODS: A retrospective review of AMC (Asan Medical Center)...
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High Flow Nasal Cannula versus Nasal CPAP in Preterm Infants

Yoon SH, Kwon YH, Park HK, Kim CR, Seol IJ, Lee HJ

PURPOSE: The aim of the study was to investigate the change in usage and clinical outcomes of using a humidified high flow nasal cannula (HHFNC) in preterm infants. METHODS: A retrospective...
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Successful Opening of Ductus Arteriosus with Milrinone in a Newborn with Tetralogy of Fallot and Pulmonary Atresia

Won CB, Kim MY, Choi DY, Cho HJ, Shim SY, Son DW

Tetralogy of Fallot (TOF) assumes its' most severe form when accompanied by pulmonary atresia (PA). Preserving the patent ductus arteriosus to maintain pulmonary blood flow is life-saving for patients with...
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A Rare Case of Scimitar Syndrome Accompanied with an Imperforate Anus in a Newborn

Chun P, Lee HD, Kim YD

Scimitar syndrome (SS) is a rare congenital anomaly characterized by hypoplasia of the right lung and partially anomalous pulmonary venous drainage to the inferior vena cava. The term scimitar derives...
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Late-onset Hypotension and Late Circulatory Collapse Due to Adrenal Insufficiency in Preterm Infants with Gestational Age Less than 32 Weeks

Lee JA, Choi CW, Kim EK, Kim HS, Kim BI, Choi JH

PURPOSE: Late-onset hypotension in preterm infants is not a rare condition. Late circulatory collapse due to adrenal insufficiency (AI) is one of the major causes of late-onset hypotension. We assessed...
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A Case of Acrodermatitis Enteropathica with Normal Serum Zinc Level in a Breastfed Preterm Infant

Baek JH, Park C, Park KH, Lee JH, Hong YS, Lee JW, Baek YS, Song HJ, Lee JH

Acrodermatitis enteropathica due to zinc deficiency is characterized by periorificial dermatitis, alopecia, and intractable diarrhea. Here we report a case of transient acrodermatitis enteropathica in a 2-month-old preterm infant, whose...
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Surfactant Replacement Therapy for RDS: a Collaborative Study of 72 Multi-center Trials in Korea (2010) and a Review of Korean Experiences over 20 Years

Bae CW, Hahn WH, Chang JY, Kim SM

In Korea, pulmonary surfactant (PS) replacement therapy in respiratory distress syndrome (RDS) was started in 1991 since when Surfacten(R) was imported from Japan. At the present time, Surfacten(R), Newfactan(R), Curosurf(R),...
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Association of Positive Ureaplasma in Gastric Fluid with Clinical Features in Preterm Infants

Jung YJ

PURPOSE: The purpose of the present study was to determine the association of positive Ureaplasma urealyticum in gastric fluid with clinical features and outcomes in preterm infants. METHODS: Gastric fluid from...
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Effects of Ibuprofen and Indomethacin for Prophylaxis of Patent Ductus Arteriosus in Premature Infants

Jeon BS, Kwon KA, Park KH, Byun SY, Kim MJ

PURPOSE: The aim of our study was to compare the efficacy and safety of ibuprofen and indomethacin in the prophylaxis of patent ductus arteriosus (PDA) in preterm infants and to...
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The Effect on Pulmonary Indices of Surfactant Therapy for Meconium Aspiration Syndrome: Systematic Review and Meta-analysis

Choi HJ, Hahn S, Lee SM, Kim HS, Bae CW

PURPOSE: Surfactants have been used to improve oxygenation for infants with meconium aspiration syndrome (MAS). We evaluated the change of pulmonary indices after surfactant therapy for MAS through a systematic...
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Giant Brain Abscess in a Neonate: Good Outcome with Single Transfontanelle Aspiration and Antibiotic Therapy

Ko JH, Choi YM, Shim KS, Bae CW, Chung SJ, Bang JS, Yoon KL

Brain abscesses in neonates are extremely rare and usually occur in patients with certain risk factors. A 1-month-old boy presented at the hospital with fever and irritability. As a result...
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Risk Factors for Hearing Loss in Very Low Birth Weight Infants: Results of Hearing Test in Infants <1,500 g

Sung MJ, Han YM, Park KH, Lee IW, Byun SY

PURPOSE: An association between very low birth weight infants(VLBWI) and hearing loss has long been recognized. Early identification and intervention for hearing loss benefits language and speech/cognitive development. We investigated...
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Clinical Course of Aplasia Cutis Congenita

Kim JY, Lee YK, Ko SY, Kim KA, Shin SM

PURPOSE: Aplasia cutis congenita (ACC) is a rare condition characterized by a localized absence of skin, and it can be associated with other congenital anomalies. This study was done to evaluate...
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