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Current Status and Importance of Clinical Research Involving Neonates

Cho SJ

  • KMID: 1477462
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):113-118.
Clinical trials in neonates of different gestational age, birth weight, postnatal age and general health status are needed to assure safe and optimal evidence-based-therapy to this special population. Pharmacodynamic maturation...
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A Case of Gallbladder Stones Associated with Anti-E Antibody Hemolytic Disease in a Neonate

Lee HJ, Hong SS, Sim YH, Kim ER

  • KMID: 1477473
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):190-195.
Cholelithiasis is rarely recognized in children, especially in infants. Hemolytic disorders, long-term total parenteral nutrition (TPN), congenital anomalies of the biliary tree leading to stasis of bile flow, congenital IgA-deficiency,...
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Perianal Ulcerative Hemangioma Treated with a Colostomy

Choi JY, Bin JH, Hahn SH, Kim SY, Kim HH, Lee WB, Lee DS

  • KMID: 1477470
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):172-175.
Hemangioma is the most common benign tumor of infancy. Greater than 60% of hemangiomas occur on the head and neck, and have an uncomplicated course. In contrast, most complicated hemangiomas...
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A Case of Non-immune Hydrops Fetalis due to Congenital Syphilis

Jung JS, Park SW, Kim CS, Lee SL, Kwon TC

  • KMID: 1477476
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):207-211.
Congenital syphilis is a rare cause of non-immune hydrops fetalis. We cared for a neonate with hydrops fetalis who was delivered by emergency Cesarean section due to prolonged fetal bradycardia...
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Outcomes of Extremely Low Birth Weight Infants at the Asan Medical Center between 2003 and 2006

Park MR, Lee BS, Kim EA, Kim KS, Pi SY

  • KMID: 1477464
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):123-133.
PURPOSE: The purpose of this study was to determine the outcomes of extremely low birth weight infants (ELBWI) who were born at the Asan Medical Center and evaluate the recent...
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Good Clinical Practice in Neonatal Clinical Research

Park MS

  • KMID: 1477463
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):119-122.
Clinical research is a necessity, not an option, for developing better and new medicines and therapeutic modalities. But in the course of clinical research, there are rules and guidelines that...
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A Case of an Addition of Chromosome 9 Short Arm Associated with Multiple Congenital Anomalies

Chang SG, Yu JE, Park MS, Lim YJ, Yoon SH, Hong J

  • KMID: 1477475
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):200-206.
Human chromosome 9 is characterized by a high degree of morphologic heteromorphisms, including variation in the size of the heterochromatin. We present a case of a de novo short arm...
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Neonatal Intestinal Pseudo-obstruction Associated with Deficiency of the Interstitial Cells of Cajal in a Premature Infant

Lee SJ, Lee WR

  • KMID: 1477474
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):196-199.
The interstitial cells of Cajal are the pacemakers in the gastrointestinal tract that modulate gastrointestinal motility. A case of a neonate with intestinal pseudo-obstruction caused by a decreased number of...
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A Congenital Giant Hepatic Hemangioendothelioma Treated with Interferon-alpha and Complete Tumor Resection

Cho MA, Yu JE, Park MS, Park JE, Hong J, Kim YB

  • KMID: 1477472
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):183-189.
Infantile hepatic hemangioendotheliomas (IHHEs) are benign vascular tumors, but can be associated with the life-threatening complications, such as congestive heart failure, disseminated intravascular coagulation, and massive bleeding. Various therapeutic options...
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Symptomatic Spontaneous Pneumothorax in the Newborn : Comorbidities and Outcomes

Joo JW, Yang EM, Sohn YJ, Kim MJ, Song ES, Choi YY, Byun HS

  • KMID: 1477469
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):166-171.
PURPOSE: This study was performed to determine the rate of neonatal symptomatic spontaneous pneumothorax, and the corresponding clinical characteristics, co-morbidities, and outcomes. METHODS: The demographic characteristics, clinical symptoms and signs, associated...
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A Case of Congenital Intrahepatic Portosystemic Shunt Associated with VSD Detected by Antenatal Sonography and Treated with Four Coil Embolizations and Open Heart Surgery after Birth

Na JY, Kim ES, Kim SD, Kim EK, Kim HS, Choi JH, Chung JE, Joung JU

  • KMID: 1477471
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):176-182.
A congenital portosystemic shunt is a very rare portosystemic vascular anomaly which leads to jaundice, hypoglycemia, hyperammonemia, liver cirrhosis, hepatic coma, and pulmonary hypertension. Anatomically, portosystemic shunts are divided into...
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Correlation between Cephalhematomas and Intracranial Hematomas

Park SM, Oh KW, Kim HM

  • KMID: 1477468
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):160-165.
PURPOSE: Cephalhematomas rarely lead to serious complications, such as skull fractures and intracranial hematomas, so CT and/or MRI scans are indicated only in cases in which depressed fractures are suspected...
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Oxygen Desaturation during Nutritive Sucking in Premature Infants with Bronchopulmonary Dysplasia: Its Effect on Feeding and Growth until 4 Months of Corrected Age

Lim CH, Lee JY, Lee HS, Lee JH, Kim SY, Sung IK, Chun CS

  • KMID: 1477465
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):134-141.
PURPOSE: This study examined the occurrence of oxygen desaturation events during nutritive sucking in premature infants with bronchopulmonary dysplasia (BPD) and its effects on feeding and growth outcomes until 4...
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Comparison of the Therapeutic Effects of Curosurf(R) and Newfactan(R) in Respiratory Distress Syndrome

Hong SW, Lee EH, Kim SY, Park HJ

  • KMID: 1477466
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):142-150.
PURPOSE: The aim of this study was to compare the clinical effects of modified porcine (Curosurf(R)) and bovine (Newfactan(R)) surfactants in the treatment of neonatal respiratory distress syndrome. METHODS: Between April...
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Analysis of Prenatal and Postnatal Factors Associated with Complications and Prognosis in Premature Infants with Leukemoid Reaction

Kwon SH, Lee BK, Lee HJ, Na SY, Lee JH, Park SY, Kang EK, Kim DH, Lee K, Kim HS

  • KMID: 1477467
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):151-159.
PURPOSE: This study determined the prenatal and postnatal factors associated with complications and prognosis in premature infants with leukemoid reaction. METHODS: We retrospectively reviewed the medical records of premature infants with...
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