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Redox Regulating Protein APE1/Ref-1 Expression is Increased in Abdominal Aortic Coarctation-induced Hypertension Rats

Song SH, Cho EJ, Park MS, Lee YR, Joo HK, Kang G, Kang SK, Choi S, Jeon BH

  • KMID: 2330961
  • J Korean Soc Hypertens.
  • 2012 Sep;18(3):126-135.
BACKGROUND: Aim of study is designed to investigate whether apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE1/Ref-1) expression is changed in abdominal aortic coarctation models. METHODS: Male Sprague-Dawley rats were randomly assigned with abdominal aortic...
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Cardiac Mitochondrial Integrity Is Regulated by CR6-interacting Factor 1 in the Heart

Jin SA, Lee YD, Yoon JY, Kim SK, Ahn KT, Park SJ, Kim JH, Park JH, Lee JH, Choi SW, Seong IW, Jeong JO

  • KMID: 2330960
  • J Korean Soc Hypertens.
  • 2012 Sep;18(3):117-125.
BACKGROUND: The major cause of metabolic syndrome and diabetes is reduced cellular performances in fuel metabolism, but the underlying pathways and mechanisms are not completely understood. Dysregulation of energy homeostasis...
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Effect of Small Hairpin RNA Molecules Targeting Angiotensin-converting Enzyme Gene in Spontaneously Hypertensive Rats

Hong YM, Lee HR, Kim KC

  • KMID: 2330959
  • J Korean Soc Hypertens.
  • 2012 Sep;18(3):105-116.
BACKGROUND: Interfering RNA (iRNA) represents a recent breakthrough in effective blocking of the target genes in mammalian cells. Angiotensin-converting enzyme (ACE) has been shown to play an important role in...
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Physician's Awareness and Education for Patient on Life Style Modification and Home Blood Pressure Monitoring Recommended in Hypertension Guideline

Kim DY, Kim SH, Kim HJ, Jung SM, Ryu KH

  • KMID: 2330958
  • J Korean Soc Hypertens.
  • 2012 Sep;18(3):97-104.
BACKGROUND: It is important to understand physicians' awareness and knowledge on hypertension guideline to comprehend physician oriented barrier against proper hypertension management. Current guidelines emphasize on the role of home...
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Pharmacokinetic and Pharmacodynamic Study Determines Factors Affecting Blood Pressure Response to Valsartan

Cho JM, Yim SV, Jin H, Sohn IS, Hwang HJ, Park CB, Jin ES, Kim CJ

  • KMID: 2330957
  • J Korean Soc Hypertens.
  • 2012 Sep;18(3):88-96.
BACKGROUND: Valsartan is an angiotensin II receptor blocker and is used for patient with hypertension. Although response to valsartan varies each individual, there is no study about factors affecting the...
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Blood Pressure Variability and Vascular Dysfunction in Essential Hypertension

Okumura K, Cheng XW

  • KMID: 2330956
  • J Korean Soc Hypertens.
  • 2012 Sep;18(3):75-87.
There are several aspects of blood pressure. Clinically, how to best assess blood pressure average and variability is still a matter of the ongoing debate. Besides office blood pressure, we...
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