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Abdominoperineal Resection in the Treatment of Locally-advanced Low Rectal Cancer: Is Preoperative Chemoradiation Advantageous?

Kim JY, Kim JS, Kim YW, Hur H, Min BS, Kim NK

PURPOSE: An abdominoperineal resection (APR) has a poor prognosis. However, limited studies about the prognostic factors in APR and the role of preoperative chemoradiotherapy (CRT) have been performed even though...
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ERRATUM: Expression of LDH-5 in Colorectal Carcinomas: Correlation with Prognosis and Tumor Angiogenesis

Ahn TS, Kim CJ, Jung DJ, Park DG, Cho SW, Kim SY, Lee MS, Kim CH, Cho MS, Baek MJ

No abstract available.
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Rectal Lymphogranuloma Venereum in a Man Who Had Sex with Men

Kim DD

We present the case of a 41-yr-old homosexual man who was managed for suspected rectal cancer before lymphogranuloma venereum was clinically diagnosed. At first, he presented with constipation and tenesmus...
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Fast-Track Colorectal Surgery

Lee IK

Conventional treatment after intra-abdominal surgery has emphasized prolonged rest of the gastrointestinal tract. The postoperative patient suffers a certain amount of functional or nutritional decline. However, using the fast-track protocol...
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A Case of Intra-abdominal Heterotopic Paragonimiasis Combined with Rectal Cancer

Kim SH, Kim HJ, Lee JI, Kye BH, Oh SN, Jung CK, Kang WK, Kim JG, Oh ST

Paragonimus westermani is a lung fluke that is usually found in the lungs, but may be found in unusual locations. A case of omental and mesenteric paragonimiasis was found incidentally...
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Usefulness of an Open Cecostomy in the Treatment of a Distal Colon Obstruction

Kuk JC, Jung EJ, Ryu CG, Moon SM, Hwang DY

PURPOSE: Stoma formation has usually been used for bowel decompression or fecal diversion. For these, a cecostomy is rarely performed because of disadvantages such as incomplete fecal diversion or fatal...
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Microsatellite Instability-low Colorectal Carcinomas: Are They Comparable with Microsatellite Stable Cancer?

Paek OJ, Oh SY, Kim YB, Suh KW

PURPOSE: Microsatellite instability-high (MSI-H) colorectal cancer (CRC) displays a well-described distinct phenotype, but the true biological significance of MSI-low (L) is still uncertain. To clarify the significance of this MSI-L,...
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Anticancer Effects of IP6 in a Human Colon Carcinoma Cell Line in Nude Mice Xenografts

Kim CD, Lee JE, Lee RA, Kim KH

PURPOSE: Inositol hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate that has been shown to suppress the growth of epithelial cancer. Because IP6 is a dietary phytochemical present in cereals,...
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Electrophysiological Characteristics of Human Colon Circular Muscle

Choe EK, Ryoo SB, Moon SH, Moon JS, Park KJ

PURPOSE: Interstitial cells of Cajal (ICC) play a core function in colonic motility as a pacemaker by regulating the slow wave. We intended to investigate the electrophysiological characteristics of the...
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Efficacy of Transparent Cap-attached Colonoscopy: Does It Improve the Quality of Colonoscopy?

Choi DH, Shin HK, Lee YC, Lim CH, Jeong SK, Lee SH, Yang HK

PURPOSE: Recently, the use of a transparent cap attached to the tip of the colonoscope has been revealed to be helpful in both detecting colorectal polyps and shortening the intubation...
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Invasiveness of and Drug Sensitivity to Various Anti-cancer Regimens in Five Colorectal Cancer Cell Lines

Lee YM, Yoon YS, Roh SA, Cho DH, Kim JC

PURPOSE: Colorectal cancer (CRC) is one of the leading causes of cancer death in South Korea. Angiogenesis has been associated with invasion and metastasis of tumors and with the secretion...
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Capecitabine-based Neoadjuvant Chemoradiation Therapy in Locally-advanced Rectal Cancer

Choi HJ, Park KJ, Lee TM, Ha SS, Lee HY, Lee HS

PURPOSE: The aim of the study was to evaluate the efficacy and the toxicity of preoperative treatment with capecitabine in combination with radiation therapy (RT) in patients with locally-advanced, resectable...
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A Prospective, Multicenter, Randomized Trial for Duration of the Prophylactic Antibiotics after Elective Colorectal Surgery: 3 Days versus 5 Days

Park JW, Oh JH, Choi HS, Yoo SB, Choe YJ, Park S, Kim JM, Lee KY, Sohn SK, Yun HR, Chun HK, Lee WY

PURPOSE: The use of prophylactic antibiotics in elective colorectal surgery is essential. Although postoperative prophylactic antibiotics are recommended within 24 hr, the optimal duration of the use of prophylactic antibiotics...
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