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Microglial involvement in the development of olfactory dysfunction

Seo Y, Kim HS, Kang KS

Olfactory impairment is the most common clinical manifestation among the elderly, and its prevalence increases sharply with age. Notably, growing evidence has shown that olfactory dysfunction is the first sign...
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Double filtration plasmapheresis in the treatment of hyperproteinemia in dogs affected by Leishmania infantum

Perondi F, Brovida C, Ceccherini G, Guidi G, Lippi I

Three dogs were evaluated for severe hyperproteinemia and hyperglobulinemia secondary to Leishmania infantum. Double filtration plasmapheresis (DFPP) was performed in two dogs at days 1, 2, and 6 after presentation....
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Ultrasonographic ovarian dynamic, plasma progesterone, and non-esterified fatty acids in lame postpartum dairy cows

Melendez P, Gomez V, Bothe H, Rodriguez , Velez J, Lopez H, Bartolome , Archbald L

The objective of this study was to compare ovulation rate, number of large ovarian follicles, and concentrations of plasma progesterone (P4) and non-esterified fatty acids (NEFA) between lame (n =...
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Comparison of the effects of isoflurane versus propofol-remifentanil anesthesia on oxygen delivery during thoracoscopic lung lobectomy with one-lung ventilation in dogs

Park J, Lee HB, Jeong SM

This study compared effects of isoflurane inhalation (ISO) and propofol-remifentanil combined total intravenous anesthesia (TIVA) on oxygenation during thoracoscopic lung lobectomy with 30-min one-lung ventilation (1LV). Thoracoscopic right middle lung...
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Dembo polymerase chain reaction technique for detection of bovine abortion, diarrhea, and respiratory disease complex infectious agents in potential vectors and reservoirs

Rahpaya SS, Tsuchiaka , Kishimoto , Oba M, Katayama Y, Nunomura Y, Kokawa S, Kimura T, Kobayashi , Kirino Y, Okabayashi T, Nonaka N, Mekata H, Aoki H, Shiokawa M, Umetsu M, Morita T, Hasebe A, Otsu K, Asai T, Yamaguchi , Makino S, Murata Y, Abi AJ, Omatsu T, Mizutani T

Bovine abortion, diarrhea, and respiratory disease complexes, caused by infectious agents, result in high and significant economic losses for the cattle industry. These pathogens are likely transmitted by various vectors...
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Prevalence, toxin gene profile, antibiotic resistance, and molecular characterization of Clostridium perfringens from diarrheic and non-diarrheic dogs in Korea

Chon JW, Seo KH, Bae D, Park JH, Khan S, Sung K

Clostridium perfringens causes diarrhea and other diseases in animals and humans. We investigated the prevalence, toxin gene profiles, and antibiotic resistance of C. perfringens isolated from diarrheic dogs (DD) and...
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Toward the development of a one-dose classical swine fever subunit vaccine: antigen titration, immunity onset, and duration of immunity

Madera RF, Wang L, Gong W, Burakova Y, Buist S, Nietfeld J, Henningson J, Cino-Ozuna AG, Tu C, Shi J

Highly contagious classical swine fever (CSF) remains a major trade and health problem in the pig industry, resulting in large economic losses worldwide. In CSF-endemic countries, attenuated CSF virus (CSFV)...
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Ovary and vaginal epithelium dynamics during the estrous cycle in Dasyprocta prymnolopha Wagler, 1831: ultrasound and cytological examinations

Carreiro A, Diniz JA, Souza JG, Araújo DV, Dias RF, Azerêdo L, Rocha EF, La Salles , Peña-Alfaro CE, Carvalho M, Illera MJ, Menezes DJ

The objective of the present study was to monitor and characterize morphological alterations in ovaries of agouti (Dasyprocta prymnolopha), reared in captivity, by using abdominal ultrasonography. All animals underwent daily...
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Marek's disease vaccine activates chicken macrophages

Wang D, Sun S, Heidari M

To provide insights into the role of innate immune responses in vaccine-mediated protection, we investigated the effect of Marek's disease (MD) vaccine, CVI988/Rispens, on the expression patterns of selected genes...
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Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China

Shen H, Liu X, Zhang P, Wang L, Liu Y, Zhang L, Liang P, Song C

Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with...
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Identification, sequence analysis, and infectivity of H9N2 avian influenza viruses isolated from geese

Zhu R, Yang X, Zhang J, Xu D, Fan J, Shi H, Wang S, Liu X

The subtype H9N2 avian influenza virus greatly threatens the Chinese poultry industry, even with annual vaccination. Waterfowl can be asymptomatically infected with the H9N2 virus. In this study, three H9N2...
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Effect of immunization routes and protective efficacy of Brucella antigens delivered via Salmonella vector vaccine

Lalsiamthara J, Won G, Lee JH

An anti-Brucella vaccine candidate comprised of purified Brucella lipopolysaccharide (LPS) and a cocktail of four Salmonella Typhimurium (ST)-Brucella vectors was reported previously. Each vector constitutively expressed highly conserved Brucella antigens...
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Production of transgenic pigs using a pGFAP-CreER(T2)/EGFP(LoxP) inducible system for central nervous system disease models

Hwang SU, Eun K, Yoon JD, Kim H, Hyun SH

Transgenic (TG) pigs are important in biomedical research and are used in disease modeling, pharmaceutical toxicity testing, and regenerative medicine. In this study, we constructed two vector systems by using...
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Clinical assessment after human adipose stem cell transplantation into dogs

Lee SH, Setyawan E, Choi YB, Ra JC, Kang SK, Lee BC, Kim GA

Adipose tissue-derived stem cell (ASCs) are an attractive source of stem cells with therapeutic applicability in various fields for regenerating damaged tissues because of their stemness characteristics. However, little has...
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Phenotypic and genotypic analyses of an attenuated porcine reproductive and respiratory syndrome virus strain after serial passages in cultured porcine alveolar macrophages

Lee SC, Lee S, Yoo GW, Choi HW, Noh YH, Park CE, Shin JH, Yoon IJ, Kang SY, Lee C

The porcine reproductive and respiratory syndrome virus (PRRSV) is a globally ubiquitous swine viral pathogen that causes major economic losses worldwide. We previously reported an over-attenuated phenotype of cell-adapted PRRSV...
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Association between endotoxin levels in dust from indoor swine housing environments and the immune responses of pigs

Roque K, Shin KM, Jo JH, Lim GD, Song ES, Shin SJ, Gautam R, Lee JH, Kim YG, Cho AR, Kim CY, Kim HJ, Lee MS, Oh HG, Lee BC, Kim JH, Kim KH, Jeong HK, Kim HA, Heo Y

Indoor animal husbandry environments are inevitably contaminated with endotoxins. Endotoxin exposure is associated with various inflammatory illnesses in animals. This cross-sectional study evaluated the relationship between the degree of endotoxin...
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Genomic characterization and pathogenic study of two porcine reproductive and respiratory syndrome viruses with different virulence in Fujian, China

Sui X, Xin T, Guo X, Jia H, Li M, Gao X, Wu J, Jiang Y, Willems L, Zhu H, Hou S

Two strains of porcine reproductive and respiratory syndrome virus (PRRSV) were isolated in 2006 and 2016 and designated as FZ06A and FZ16A, respectively. Inoculation experiments showed that FZ06A caused 100%...
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Analysis of swine leukocyte antigen class I gene profiles and porcine endogenous retrovirus viremia level in a transgenic porcine herd inbred for xenotransplantation research

Matczyńska D, Sypniewski D, Gałka S, Sołtysik , Loch T, Nowak E, Smorąg Z, Bednarek I

Molecular characterization of swine leukocyte antigen (SLA) genes is important for elucidating the immune responses between swine-donor and human-recipient in xenotransplantation. Examination of associations between alleles of SLA class I...
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