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Composite follicular lymphoma and classic Hodgkin lymphoma

Kim HN, Jeon MJ, Yu ES, Kim DS, Choi CW, Ko YH

Composite lymphoma is very rare and a combination of Hodgkin lymphoma and non-Hodgkin lymphoma and even histiocytic tumors can occur. Because of the unfamiliarity, not only can this cause diagnostic...
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Chronic lymphocytic leukemia and concurrent seminoma in the same testis

Miyai K, Kumazawa F, Sato K, Tsuda H

A 59-year-old man presented with a painless testicular mass and underwent a radical orchiectomy. The resected specimen showed a 5-cm-sized, white-yellow and homogenous solid mass in the testicular parenchyma. Histologically,...
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TTF1-positive SMARCA4/BRG1 deficient lung adenocarcinoma

Mehta A, Diwan H, Bansal D, Gupta M

SMARCA4/BRG1-deficient lung adenocarcinoma (SD-LUAD) is being recognized as a distinct subtype based on subtle differences in its clinical, morphological, and immunophenotypic attributes compared to other non–small cell lung carcinomas. We...
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Association of PTTG1 expression with invasiveness of non-functioning pituitary adenomas

Kum SJ, Lee HW, Kim SG, Park H, Hwang I, Kim SP

Background: Pituitary tumor transforming gene 1 (PTTG1), paired-like homeodomain 2 (PITX2), and galectin-3 have been widely studied as predictive biomarkers for various tumors and are involved in tumorigenesis and tumor...
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Follicular lymphoma: updates for pathologists

Khanlari M, Chapman JR

Follicular lymphoma (FL) is the most common indolent B-cell lymphoma and originates from germinal center B-cells (centrocytes and centroblasts) of the lymphoid follicle. Tumorigenesis is believed to initiate early in...
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Clinicopathological differences in radiation-induced organizing hematomas of the brain based on type of radiation treatment and primary lesions

Kim MS, Kim SH, Chang JH, Park M, Cha YJ

Background: Radiation-induced organizing hematoma (RIOH) is a sporadic form of cavernous hemangioma (CH) that occurs after cerebral radiation. RIOH lesions are distinct histologically from de novo CH; however, detailed research...
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Polo-like kinase 4 as a potential predictive biomarker of chemoradioresistance in locally advanced rectal cancer

Oh H, Kim SG, Bae SU, Byun SJ, Kim S, Lee JH, Hwang I, Kwon SY, Lee HW

Background: Polo-like kinase 4 (PLK4) is a serine/threonine protein kinase located in the centriole of the chromosome during the cell cycle. PLK4 overexpression has been described in a variety of...
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Clinicopathologic implication of PD-L1 gene alteration in primary adrenal diffuse large B cell lymphoma

Lee KR, Koh J, Jeon YK, Kwon HJ, Lee JO, Paik JH

Background: Primary adrenal (PA) diffuse large B cell lymphoma (DLBCL) was previously reported as an aggressive subset of DLBCL, but its genetic features were not sufficiently characterized. From our previous...
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