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What’s new in gynecologic pathology 2021: ovary and fallopian tube

Turashvili G, Lastra R

The 5th edition of the World Health Organization (WHO) Classification of Female Genital Tumors was published in 2020. Although the classification of ovarian and fallopian tube neoplasms is largely unchanged...
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Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis

Lee J, Cho Y, Choi KH, Hwang I, Oh YL

Metastatic leiomyosarcoma to the thyroid is an extremely rare occurrence, and only 18 cases have been reported. Here, we report a case of a 37-year-old woman who presented with multiple...
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Appendiceal actinomycosis mimicking appendiceal tumor, appendicitis or inflammatory bowel disease

Sung YN, Kim J

Appendiceal actinomycosis is very rare and its diagnosis is often difficult even in surgically resected specimens. Here we report two cases of appendiceal actinomycosis confirmed by pathologic examination of surgically...
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Proto-oncogene Pokemon in thyroid cancer: a potential promoter of tumorigenesis in papillary thyroid carcinoma

Chang K, Do SI, Kim K, Chae SW, Do Ig, Lee HJ, Kim DH, Sohn JH

Background: Pokemon is an oncogenic transcription regulator that plays a critical role in cellular differentiation. Although it has been found to be overexpressed in several types of cancer involving different...
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Primary hepatic mixed germ cell tumor in an adult

Sung HJ, Kim J, Kim Kr, Yoon S, Lee JH, Kang HJ

Primary hepatic mixed germ cell tumor (GCT) is very rare, and less than 10 cases have been reported. We report a case of mixed GCT composed of a choriocarcinoma and...
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Prognostic significance of viable tumor size measurement in hepatocellular carcinomas after preoperative locoregional treatment

Hwang YJ, Lee Y, Park H, Lee Y, Lee K, Kim H

Background: Preoperative locoregional treatment (LRT) for hepatocellular carcinoma (HCC) often induces intratumoral necrosis without affecting the overall tumor size, and residual viable tumor size (VTS) on imaging is an important...
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Upward trend in follicular lymphoma among the Korean population: 10-year experience at a large tertiary institution

Kim M, Hwang HS, Cho H, Yoon DH, Suh C, Park CS, Go H, Huh J

Background: Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma (NHL) in Western countries. However, it is relatively rare in Asia. This study examined epidemiologic characteristics of FL in...
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SMARCA4/BRG1 protein-deficient thoracic tumors dictate re-examination of small biopsy reporting in non–small cell lung cancer

Mehta A, Bansal D, Tripathi R, Jajodia A

Background: SMARCA4/BRG1 protein–deficient lung adenocarcinomas and thoracic sarcoma are recently described entities that lack distinctive histological features, transcription termination factor 1 (TTF1) reactivity, and actionable driver mutations. The current diagnostic...
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Robust home brew fragment sizing assay for detection of MET exon 14 skipping mutation in non–small cell lung cancer patients in resource constrained community hospitals

Mehta A, Nathany S, Chopra A, Mattoo S, Kumar D, Panigrahi MK

Background: A mutation/deletion involving donor or acceptor sites for exon 14 results in splicing out of exon 14 of the mesenchymal epithelial transition (MET) gene and is known as “MET...
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