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DNA-protein biomarkers for immunotherapy in the era of precision oncology

Kim B, Kang SY, Kim KM

The use of biomarkers to guide patient and therapy selection has gained much attention to increase the scope and complexity of targeted therapy options and immunotherapy. Clinical trials provide a...
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Standardized pathology report for breast cancer

Cho SY, Park SY, Bae YK, Kim JY, Kim EK, Kim WG, Kwon Y, Lee A, Lee HJ, Lee JS, Park JY, Gong G, Yoon HK

Given the recent advances in management and understanding of breast cancer, a standardized pathology report reflecting these changes is critical. To meet this need, the Breast Pathology Study Group of...
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EGFR-mutated pulmonary adenocarcinoma with concurrent PIK3CA mutation, and with acquired RET fusion and EGFR T790M mutation after afatinib therapy

Kim M, Na JM, Lee GW, Lee SJ, Kim JD, Yang JW

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Fibrocartilaginous mesenchymoma with an unusual location in the rib

Oh SJ

Fibrocartilaginous mesenchymoma is a rare bone tumor, with fewer than 35 cases reported in the literature since 1984. This tumor usually occurs in the long bones of children and adolescents....
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Imaging features of breast cancer molecular subtypes: state of the art

Cho N

Characterization of breast cancer molecular subtypes has been the standard of care for breast cancer management. We aimed to provide a review of imaging features of breast cancer molecular subtypes...
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A case of cribriform carcinoma of the skin: a newly described rare condition

Lee H, Won CH, Park CS

Primary cribriform carcinoma of the skin is an indolent, rare, adnexal tumor. Although its malignant potential remains uncertain, no recurrence or metastasis has been reported. A 33-year-old man presented with...
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Causes of necrotic features in fine-needle aspirates from cervical lymph nodes

Seo YJ, Shin H, Lee HW, Jung HR

Background: Lymph node fine-needle aspiration (LN FNA) cytology indicates necrosis in various diseases. Dominant necrotic features make the diagnosis of underlying conditions very difficult. Methods: We retrospectively reviewed 460 patients who...
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Interobserver diagnostic reproducibility in advanced-stage endometrial carcinoma

Jung HJ, Lee SY, Hong JH, Chun YK

Background: The accurate pathologic diagnosis and subtyping of high-grade endometrial carcinoma are often problematic, due to its atypical and overlapping histopathological features. Methods: Three pathologists reviewed 21 surgically resected cases of...
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A comparative prognostic performance of definitions of Crohn-like lymphoid reaction in colorectal carcinoma

Kim Y, Bae JM, Kim JH, Cho NY, Kang GH

Background: The prognostic potential of Crohn-like lymphoid reaction (CLR) in colorectal carcinoma (CRC) has been investigated through the assessment of different criteria. Methods: The prognostic impact of CLR was investigated in...
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Automated immunohistochemical assessment ability to evaluate estrogen and progesterone receptor status compared with quantitative reverse transcription-polymerase chain reaction in breast carcinoma patients

Jeon T, Kim A, Kim C

Background: This study aimed to investigate the capability of an automated immunohistochemical (IHC) evaluation of hormonal receptor status in breast cancer patients compared to a well-validated quantitative reverse transcription–polymerase chain...
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