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The Implications of Mucosal Integrity and Microinflammation in the Pathogenesis of Gastroesophageal Reflux Disease

Shin CM

  • KMID: 2557962
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):257-258.
  • doi: 10.5056/jnm24086
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Diet, Physical Activity, and Chronic Constipation: Unveiling the Combined Effects for Better Treatment Strategies

Kim SJ

  • KMID: 2557961
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):255-256.
  • doi: 10.5056/jnm24085
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Esophageal Mucosal Impedance Assessment: Clinical Usefulness for Diagnosis of Gastroesophageal Reflux Disease

Kim SH

  • KMID: 2557960
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):253-254.
  • doi: 10.5056/jnm24080
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Predicting Response to Low Fermentable Oligo-, Di-, Mono-saccharides, and Polyols Diet in Patients With Abdominal Bloating Using Hydrogen Methane Breath Test: Is a Spot Sample Enough?

Ghoshal UC, Mustafa U, Mukhopadhyay SK, Goenka MK

  • KMID: 2557975
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):379-380.
  • doi: 10.5056/jnm24009
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Comparison of Gas-sensing Capsule With Wireless Motility Capsule in Motility Disorder Patients

Zhou J, Thwaites PA, Gibson PR, Burgell R, Ho V

  • KMID: 2557967
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):303-312.
  • doi: 10.5056/jnm23157
Background/Aims Motility disorders are prevalent, often leading to disrupted regional or whole gut transit times. In this study, we conducted a comparative analysis between the wireless motility capsule and an innovative...
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Impact of Esophageal Motility on Microbiome Alterations in Symptomatic Gastroesophageal Reflux Disease Patients With Negative Endoscopy: Exploring the Role of Ineffective Esophageal Motility and Contraction Reserve

Wong MW, Lo IH, Wu WK, Liu PY, Yang YT, Chen CY, Wu MS, Wong SH, Lei WY, Yi CH, Liu TT, Hung JS, Liang SW, Gyawali CP, Chen CL

  • KMID: 2557970
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):332-342.
  • doi: 10.5056/jnm22191
Background/Aims Ineffective esophageal motility (IEM) is common in patients with gastroesophageal reflux disease (GERD) and can be associated with poor esophageal contraction reserve on multiple rapid swallows. Alterations in the esophageal...
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Effects of Cholecystokinin on Esophageal Motor Response to Distension in Asymptomatic Volunteers

Ellison AC, Kahrilas PJ, Pandolfino JE, Carlson DA

  • KMID: 2557971
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):343-351.
  • doi: 10.5056/jnm23051
Background/Aims Cholecystokinin (CCK) administration has been shown to reduce lower esophageal sphincter (LES) pressure in normal subjects in manometric studies. Functional luminal imaging probe (FLIP) panometry offers a method to assess...
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Esophageal Mucosal Impedance Assessment for the Diagnosis of Gastroesophageal Reflux Disease

Lages RB, Fontes LHdS, Barbuti RC, Navarro-Rodriguez T

  • KMID: 2557972
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):352-360.
  • doi: 10.5056/jnm23063
Background/Aims Diagnosing gastroesophageal reflux disease (GERD) is sometimes challenging because the performance of available tests is not entirely satisfactory. This study aims to directly measure the esophageal mucosal impedance during upper...
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Roles of Cytokines in Pathological and Physiological Gastroesophageal Reflux Exposure

Ergun P, Kipcak S, Gunel NS, Bor S, Sozmen EY

  • KMID: 2557966
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):290-302.
  • doi: 10.5056/jnm22186
Background/Aims Gastroesophageal reflux disease is frequently observed and has no definitive treatment. There are 2 main views on the pathogenesis of gastroesophageal reflux disease. The first is that epithelial damage starts...
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The Role of Psychological Factors in Noncardiac Chest Pain of Esophageal Origin

Gonzalez-Ibarra F, Cruz-Ruiz M, Llanes JM, Achem SR, Fass R

  • KMID: 2557964
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):272-280.
  • doi: 10.5056/jnm23166
Background/Aims Noncardiac chest pain (NCCP) of esophageal origin is a challenging clinical problem of diverse etiology that affects more than 80 million Americans yearly. We assess the prevalence and impact of...
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Consistency of Feces Affects Defecatory Function

Sun D, Lo KM, Chen SC, Leung WW, Wong C, Mak T, Ng S, Futaba K, Gregersen H

  • KMID: 2557974
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):373-378.
  • doi: 10.5056/jnm22177
Background/Aims It is a common belief that constipated patients have hard feces that contributes to the difficulties defecating. To the best of our knowledge, no studies had been published on controlled...
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Effect of Physical Activity on the Association Between Diet and Constipation: Evidence From the National Health and Nutrition Examination Survey 2007-2010

Lai S, Zhu C, Zhou X, Zeng Q, Huang L, Cao X, Zhou Q, Zhong Y, Huang J, Liu J, Zeng G, Chen H

  • KMID: 2557969
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):322-331.
  • doi: 10.5056/jnm23134
Background/Aims Previous studies have shown that diet and physical activity can influence constipation. However, the combined effect of diet and physical activity on constipation remains unclear. Methods Constipation was defined based on stool...
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Treatment Response With Potassium-competitive Acid Blockers Based on Clinical Phenotypes of Gastroesophageal Reflux Disease: A Systematic Literature Review and Meta-analysis

Seo S, Jung HK, Gyawali CP, Lee HA, Lim HS, Jeong ES, Kim SE, Moon CM

  • KMID: 2557963
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):259-271.
  • doi: 10.5056/jnm24024
Background/Aims Gastroesophageal reflux disease (GERD) is typically managed based on the clinical phenotype. We evaluated the efficacy and safety of potassium-competitive acid blockers (PCABs) in patients with various clinical GERD phenotypes. Methods Core...
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Breaking Barriers in Functional Dyspepsia: A Systematic Review and Meta-analysis on Duodenal Tight Junction Protein Expression

Farcas RA, Almasri M, Grad S, Popa SL, Leucuta DC, Ismaiel A, Dumitrascu DL

  • KMID: 2557965
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):281-289.
  • doi: 10.5056/jnm24013
Background/Aims Disruptions in tight junction (TJ) protein expression leading to duodenal epithelial barrier impairment may contribute to increased intestinal permeability, potentially playing a role in functional dyspepsia (FD) pathophysiology. Currently published...
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Efficacy of Tegoprazan in Patients With Functional Dyspepsia: A Prospective, Multicenter, Single-arm Study

Huh CW, Youn YH, Jung DH, Cha RR, Kim YJ, Jung K, Song KH, Bang KB, Tae CH, Choi SI, Shin CM, Functional Dyspepsia Research Group Under the Korean Society of Neurogastroenterology and Motility

  • KMID: 2557968
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):313-321.
  • doi: 10.5056/jnm23150
Background/Aims Acid-suppressive drugs, such as proton pump inhibitors (PPIs), are treatment options for functional dyspepsia (FD). However, the efficacy of potassium-competitive acid blockers (P-CABs) in treating FD has not yet been...
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Masculinity, Rather Than Biological Sex, Is Associated With Psychological Comorbidities in Patients With Irritable Bowel Syndrome

Kim YS, Lee JY, Kim JW, Kang SJ, Park JH, Kim HJ, Jang Sh, Kim JH, Oh JH, Brain-Gut Axis Research Group of Korean Society of Neurogastroenterology and Motility

  • KMID: 2557973
  • J Neurogastroenterol Motil.
  • 2024 Jul;30(3):361-372.
  • doi: 10.5056/jnm23012
Background/Aims Irritable bowel syndrome (IBS) generally shows sex differences, and psychiatric comorbidities play an important role in its pathogenesis. We aim to measure the levels of gender roles and investigate their relationship...
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