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Transient Receptor Potential Canonical 4 Channel in Interstitial Cells of Cajal as a Target for Control of Gastrointestinal Motility

Zhou Z, Xia M, Lv J

  • KMID: 2514688
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):302-304.
  • doi: 10.5056/jnm20267
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Integrated Relaxation Pressure During Swallowing: An Ever-changing Metric

Gong EJ

  • KMID: 2514671
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):151-152.
  • doi: 10.5056/jnm21033
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What Is the Difference in Characteristics Between Belching Disorder and Gastroesophageal Reflux Disease With Belching? Centering Around Supragastric Belching

Kim SE

  • KMID: 2514670
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):149-150.
  • doi: 10.5056/jnm21032
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There Is Something More Important Than Proximal Reflux Episode in the Development of Post-reflux Swallow-induced Peristaltic Wave

Lee TH

  • KMID: 2514689
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):305-306.
  • doi: 10.5056/jnm20276
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Inflammation and Overlap of Irritable Bowel Syndrome and Functional Dyspepsia

Wang C, Fang X

  • KMID: 2514672
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):153-164.
  • doi: 10.5056/jnm20175
Irritable bowel syndrome (IBS) and functional dyspepsia (FD) are common functional gastrointestinal disorders (FGIDs) and account for a large proportion of consulting patients. These 2 disorders overlap with each other...
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Impact of Serotonin Transporter Gene Polymorphism on Gut Motility in Patients With Type 2 Diabetes Mellitus

Malik A, Saha S, Morya RK, Bhadada SK, Rana SV

  • KMID: 2514682
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):240-247.
  • doi: 10.5056/jnm20211
Background/Aims The pathogenesis of gastrointestinal (GI) symptoms in patients with type 2 diabetes mellitus (T2DM) is yet to be delineated clearly. Serotonin, a monoamine neurotransmitter, resides primarily in the gut and plays...
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Esophageal Motility Patterns After Peroral Endoscopic Myotomy in Patients With Achalasia

Vackova Z, Mares J, Krajciova J, Rabekova Z, Zdrhova L, Loudova P, Spicak J, Stirand P, Hucl T, Martinek J

  • KMID: 2514678
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):205-214.
  • doi: 10.5056/jnm20126
Background/Aims Several studies have reported partial recovery of peristalsis in patients with achalasia after myotomy. The aim of our study is to analyze esophageal motility patterns after peroral endoscopic myotomy (POEM)...
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High-fat Diet Enhances Gastric Contractility, but Abolishes Nesfatin-1-induced Inhibition of Gastric Emptying

Özdemir-Kumral ZN, Koyuncuoğlu T, Arabacı-Tamer S, Çilingir-Kaya , Köroğlu AK, Yüksel M, Yeğen B

  • KMID: 2514685
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):265-278.
  • doi: 10.5056/jnm20206
Background/Aims Gastrointestinal motility changes contribute to development and maintenance of obesity. Nesfatin-1 (NES-1) is involved in central appetite control. The aim is to elucidate effects of NES-1 and high-fat diet (HFD)...
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Impaired Colonic Contractility and Intestinal Permeability in Symptomatic Uncomplicated Diverticular Disease

Altomare A, Gori M, Cocca S, Carotti S, Francesconi M, Ribolsi M, Emerenziani S, Perrone G, Morini S, Cicala M, Guarino MPL

  • KMID: 2514687
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):292-301.
  • doi: 10.5056/jnm20110
Background/Aims Impaired intestinal motility seems to play a crucial role in symptomatic uncomplicated diverticular disease (SUDD), although the mechanism is not clear. The aim of the present study is to explore...
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Impact of Overlapping Functional Gastrointestinal Disorders on the Quality of Life in Patients With Gastroesophageal Reflux Disease

Lee SW, Chang CS

  • KMID: 2514674
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):176-184.
  • doi: 10.5056/jnm19006
Gastroesophageal reflux disease (GERD) and functional gastrointestinal disorders (FGIDs), including irritable bowel syndrome and functional dyspepsia, are common afflictions within the general population. Both conditions have a considerable impact on...
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Alteration in Integrated Relaxation Pressure During Successive Swallows in Subjects With Normal Manometry Versus Those With Esophagogastric Junction Outflow Obstruction

Elangovan A, Shibli F, Fass R

  • KMID: 2514675
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):185-190.
  • doi: 10.5056/jnm20139
Background/Aims Integrated relaxation pressure (IRP) is defined as the average minimum esophagogastric junction pressure for 4 seconds of relaxation (contiguous or noncontiguous) within 10 seconds of swallowing. The durability of IRP...
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The Influence of Gastroesophageal Reflux Disease on Daytime Sleepiness and Depressive Symptom in Patients With Obstructive Sleep Apnea

Kang HH, Lim CH, Oh JH, Cho MJ, Lee SH

  • KMID: 2514679
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):215-222.
  • doi: 10.5056/jnm20071
Background/Aims As there is insufficient evidence for a relationship between gastroesophageal reflux disease (GERD) and obstructive sleep apnea (OSA), we investigated whether OSA diagnosed by polysomnography (PSG) is related to GERD. Methods A...
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Lactose Sensitivity and Lactose Malabsorption: The 2 Faces of Lactose Intolerance

Bouchoucha M, Fysekidis M, Rompteaux P, Raynaud JJ, Sabate JM, Benamouzig R

  • KMID: 2514684
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):257-264.
  • doi: 10.5056/jnm20094
Background/Aims Self-reported lactose intolerance (LI) is frequent in patients with functional bowel disorders (FBD) that could be interpreted as irritable bowel syndrome (IBS). The present study aims to characterize the responses...
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Usefulness of Endoscopic Hill Grade in Evaluating Children Suspected of Having Gastroesophageal Reflux Disease

Yoo IH, Joo JY, Yang HR

  • KMID: 2514676
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):191-197.
  • doi: 10.5056/jnm20033
Background/Aims This study aim to evaluate the relationship between the Hill grade confirmed by esophagogastroduodenoscopy (EGD) and the degree of gastroesophageal reflux (GER) by 24-hour multichannel intraluminal impedance-pH monitoring (MII-pH) in...
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Characteristics of Symptomatic Belching in Patients With Belching Disorder and Patients Who Exhibit Gastroesophageal Reflux Disease With Belching

Jeong SO, Lee JS, Lee TH, Hong SJ, Cho YS, Park J, Jeon SR, Kim HG, Kim JO

  • KMID: 2514681
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):231-239.
  • doi: 10.5056/jnm20114
Background/Aims Belching disorder (BD) is clinically distinct from gastroesophageal reflux disease (GERD) with belching. Supragastric belching (SGB) is closely associated with reflux episodes. This study investigates belch characteristics in association with...
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A Systematic Review and Meta-analysis of Randomized Control Trials: Combination Treatment With Proton Pump Inhibitor Plus Prokinetic for Gastroesophageal Reflux Disease

Jung DH, Huh CW, Lee SK, Park JC, Shin SK, Lee YC

  • KMID: 2514673
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):165-175.
  • doi: 10.5056/jnm20161
Background/Aims Prokinetics can be used for treating patients with gastroesophageal reflux disease (GERD), who exhibit suboptimal response to proton pump inhibitor (PPI) treatment. We conducted a systematic review to assess the...
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A Resting-state Functional Magnetic Resonance Imaging Study of Whole-brain Functional Connectivity of Voxel Levels in Patients With Irritable Bowel Syndrome With Depressive Symptoms

Li J, He P, Lu X, Guo Y, Liu M, Li G, Ding J

  • KMID: 2514683
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):248-256.
  • doi: 10.5056/jnm20209
Background/Aims Depressive symptom is one of the most common symptoms in patients with irritable bowel syndrome (IBS), but its pathogenetic mechanisms remain unclear. As a voxel-level graph theory analysis method, degree...
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Simultaneous Evaluation of Laryngopharyngeal Reflux and Swallowing Function Using Hypopharyngeal Multichannel Intraluminal Impedance Measurements in Neurologically Impaired Patients

Masui D, Fukahori S, Hashizume N, Ishii S, Higashidate N, Sakamoto S, Tsuruhisa S, Nakahara H, Saikusa N, Tanaka Y, Yagi M

  • KMID: 2514677
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):198-204.
  • doi: 10.5056/jnm20125
Background/Aims This study aims to evaluate the presence of laryngopharyngeal reflux (LPR) and to investigate the use of hypopharyngeal baseline impedance (BI) for assessing swallowing dysfunction and gastroesophageal reflux disease (GERD)...
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Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine

Jalanka J, Lam C, Bennett A, Hartikainen A, Crispie F, Finnegan LA, Cotter PD, Spiller R

  • KMID: 2514686
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):279-291.
  • doi: 10.5056/jnm20205
Background/Aims Diarrhea-predominant irritable bowel syndrome (IBS-D) has been previously associated with evidence of immune activation and altered microbiota. Our aim is to assess the effect of the anti-inflammatory agent, mesalazine, on...
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Efficacy of S-pantoprazole 10 mg in the Symptom Control of Non-erosive Reflux Disease: A Phase III Placebo-controlled Trial

Cho YK, Choi MG, Park H, Kim JW, Lee DH, Ko KH, Kim SG, Jung HY, Hong SJ, Lee YC, Lee SH

  • KMID: 2514680
  • J Neurogastroenterol Motil.
  • 2021 Apr;27(2):223-230.
  • doi: 10.5056/jnm19053
Background/Aims S-isomer (S) pantoprazole is more bioavailable and less dependent on cytochrome 2C19 than is racemic pantoprazole. We aim to evaluate the efficacy and safety of 10 mg S-pantoprazole for treatment...
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