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Impact of Upper Eyelid Surgery on Symptom Severity and Frequency in Benign Essential Blepharospasm

Timlin HM, Jiang K, Ezra DG

Objective To assess the impact of periocular surgery, other than orbicularis stripping, on the severity and frequency of blepharospasm symptoms. Methods Consecutive patients with benign essential blepharospasm (BEB) who underwent eyelid/eyebrow...
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Health-Related Quality of Life for Parkinson’s Disease Patients and Their Caregivers

Lubomski M, Davis RL, Sue CM

Objective Motor and non-motor symptoms (NMS) negatively impact the health-related quality of life (HRQoL) for individuals with Parkinson’s disease (PD), as well as their caregivers. NMS can emerge decades prior...
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Impact and Challenges of the COVID-19 Pandemic on Patients Requiring Botulinum Toxin A Treatment

Pajo AT, Espiritu AI, Jamora RDG

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Immune-Mediated Cerebellar Ataxias: Clinical Diagnosis and Treatment Based on Immunological and Physiological Mechanisms

Mitoma H, Manto M, Hadjivassiliou M

Since the first description of immune-mediated cerebellar ataxias (IMCAs) by Charcot in 1868, several milestones have been reached in our understanding of this group of neurological disorders. IMCAs have diverse...
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Involuntary Movements Following Administration of Hydroxychloroquine for COVID-19 Pneumonia

Fernando EZ, Yu JRT, Santos SMA, Jamora RDG

Hydroxychloroquine (HCQ) has been used as an investigational drug for patients with moderate to severe coronavirus disease 2019 (COVID-19). There have been concerns of potential harms from side effects of...
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The Queensland Parkinson’s Project: An Overview of 20 Years of Mortality from Parkinson’s Disease

Poortvliet PC, Gluch A, Silburn PA, Mellick GD

Objective The consensus is that life expectancy for individuals with Parkinson’s disease (PD) is reduced, but estimations vary. We aimed to provide an overview of 20 years of mortality and...
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Generalized Chorea Due to Secondary Polycythemia Responding to Phlebotomy

Cherian A, Paramasivan NK, Puthanveedu DK, Krishnan S, Nair AR

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New Nonsense Variant c.2983G>T; p.Glu995* in the CACNA1A Gene Causes Progressive Autosomal Dominant Ataxia

Saathoff Y, Biskup S, Funke C, Roth C

The genetic testing of hereditary ataxias includes screening for CAG-repeat expansions as well as pathogenic variants and nontranslated oligonucleotide expansion, which can cause spinocerebellar ataxia (SCA). Genotype-phenotype correlations of several...
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Sialidosis Type I without a Cherry Red Spot— Is There a Genetic Basis?

Neeraja K, Holla VV, Prasad S, Surisetti BK, Rakesh K, Kamble N, Yadav R, Pal PK

Sialidosis is an inborn error of metabolism due to a defect in the NEU1 gene and manifests as two phenotypes: mild type I and severe type II. The cherry red...
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The Case of a Patient with Pantothenate Kinase-Associated Neurodegeneration Presenting with a Prolonged History of Stuttering Speech and a Misdiagnosis of Parkinson’s Disease

Natteru PA, Huang J

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Speech-Induced Task-Specific Cranio-Cervical Tardive Dystonia: An Unusual Phenomenology

Holla VV

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Knowledge, Attitude, and Perceptions about Deep Brain Stimulation for Parkinson’s Disease: Observations from a Single Indian Center

Prasad S, Bhattacharya A, Sahoo LK, Batra D, Kamble N, Yadav R, Srinivas D, Pal PK

Objective Willingness to undergo deep brain stimulation (DBS) among patients with Parkinson’s disease (PD) and their overall satisfaction with the procedure is highly dependent upon expectations, which are based on...
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Perry Disease: Concept of a New Disease and Clinical Diagnostic Criteria

Tsuboi Y, Mishima T, Fujioka S

Perry disease is a hereditary neurodegenerative disease with autosomal dominant inheritance. It is characterized by parkinsonism, psychiatric symptoms, unexpected weight loss, central hypoventilation, and transactive-response DNA-binding protein of 43kD (TDP-43)...
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A Rare Case of Green Gelatinous Mass Formation on a Deep Brain Stimulation Implantable Pulse Generator

Poortvliet PC, Mellick G, Coyne T, Silburn P

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COVID-19: Implications for Sudden Death in Parkinson’s Disease

Fiorini AC, Fonseca MCM, Scorza CA, Finsterer J, Rodrigues AM, de Almeida ACG, Scorza FA

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