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Survival of Korean Huntington's Disease Patients

Kim HJ, Shin CW, Jeon B, Park H

OBJECTIVE: The survival of Huntington’s disease (HD) patients is reported to be 15–20 years. However, most studies on the survival of HD have been conducted in patients without genetic confirmation...
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Falls and Their Associated Risks in Parkinson’s Disease Patients in Nigeria

Farombi TH, Owolabi MO, Ogunniyi A

OBJECTIVE: Falls are a devastating consequence of Parkinson's disease (PD) and are due to motor imbalance. However, the frequency of falls and their risk factors among Nigerians with PD is...
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The MMSE and MoCA for Screening Cognitive Impairment in Less Educated Patients with Parkinson's Disease

Kim JI, Sunwoo MK, Sohn YH, Lee PH, Hong JY

OBJECTIVE: To explore whether the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) can be used to screen for dementia or mild cognitive impairment (MCI) in less educated patients...
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Cognition and Visit-to-Visit Variability of Blood Pressure and Heart Rate in De Novo Patients with Parkinson's Disease

Kwon KY, Pyo SJ, Lee HM, Seo WK, Koh SB

OBJECTIVE: We sought to identify whether the characteristics of long-term visit-to-visit blood pressure (BP) and heart rate (HR) are related to baseline cognitive profiles in, Parkinson’s disease (PD). METHODS: We selected...
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Applications of CRISPR/Cas9 for Gene Editing in Hereditary Movement Disorders

Im W, Moon J, Kim M

Gene therapy is a potential therapeutic strategy for treating hereditary movement disorders, including hereditary ataxia, dystonia, Huntington's disease, and Parkinson's disease. Genome editing is a type of genetic engineering in...
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Episodic Ataxias: Clinical and Genetic Features

Choi KD, Choi JH

Episodic ataxia (EA) is a clinically heterogeneous group of disorders that are characterized by recurrent spells of truncal ataxia and incoordination lasting minutes to hours. Most have an autosomal dominant...
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