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Recent Advances in Immunotherapy of Lung Cancer

Iclozan C, Gabrilovich DI

Immunotherapy was long considered as an attractive modality in the treatment of lung cancer. However, clinical successes were hampered by the inability to achieve potent activation of the antitumor immune...
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Molecular Pathogenesis of Non-Small Cell Lung Carcinomas

Wistuba II

Non-small cell lung carcinoma (NSCLC) from histological and biological perspectives is a complex neoplasm. The sequential preneoplastic changes have been defined for centrally arising squamous cell carcinomas (SCCs) of the...
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Expression of Cyclin A, B1, D1, D3, and E in Non-Small Lung Cancers

Ha SY, Kim HK, Im JS, Cho HY, Chung DH, An J

PURPOSE: Cyclins, and their associated cyclin dependent kinases, regulate progression of the cell cycle through the G1 phase and into the S-phase during the DNA replication process. Cyclin E regulation...
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Expression of Transforming Growth Factor beta1 and Cadherins in Lung Adenocarcinoma

Park SY, Yoo J

PURPOSE: There is evidence supporting the concept of tumor progression from pulmonary adenocarcinoma in situ (formerly bronchioloalveolar carcinoma, BAC) to adenocarcinoma with varying degrees of invasion. The aim of this...
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A Minimal Immunohistochemical Panel for Subtyping Poorly Differentiated Non-Small Cell Lung Carcinoma: A Tissue Microarray Study Simulating Small Biopsy Conditions

Kim GY, Lim SJ, Kim WS, Lee GK

PURPOSE: Given the emerging evidence for differential responses to new targeted therapies and the identification of molecular differences between specific subtypes of non-small cell lung carcinoma (NSCLC), there is an...
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Multilocular Thymic Cyst with Prominent Lymphoid Follicular Hyperplasia: A Case Report

Yoon NR, Jeong JY, Han J, Kim J, Yi CA

We present herein an unusual case of multilocular thymic cyst, with prominent lymphoid follicular hyperplasia, in a 64-year-old man. It was incidentally founded as a mediastinal mass on chest radiography,...
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