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The Characterization of Glucocoritcoid Response Element(GRE) on the Promoter of Thyrotropin-Releasing Hormone(TRH) Gene

Kim SW, Kim JW, Kim YS, Choi YK, Yang IM, Woo JT, Chung WW

  • KMID: 2199457
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):265-277.
BACKGROUND: We previously demonstrated that the promoter of rat TRH gene has GRE half site (TGTTCT) between -210 bp and -205 bp flanking with similar sequences of TPA response element...
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Analysis of Glucocorticoid Response Element and TPA Response Element of Rat Thyrotropin-Releasing Hormine Gene by Site-Directed Mutagenesis

Kim SW, Kim JW, Kim YS, Choi YK, Yang IM, Woo JT, Chung WW

  • KMID: 2199458
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):278-292.
BACKGROUND: We previously demonstrated that a GRE/TRE composite sequence, which is located between 200 bp and 220 bp relative to the transcriptional start site of rat TRH gene, is responsible...
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Serum Leptin in Cord Blood and Its Relation with Birth Weight and Metabolic Parameters

Park DJ, Lee YY, Park KS, Kim SY, Cho BY, Lee HG, Park GS, Jun JK, Yoon BH

  • KMID: 2199467
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):365-371.
BACKGROUND: Leptin, produced in the adipose tissue, is involved in the regulation of body weight. The release of the leptin is increased in obese adults even in children. This study...
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A Case of Ioslated TSH Deficiency

Kim H, Kim WS, Choi SJ, Kim DY, Kim SH, Park SM, Lee WK, Kim YN

  • KMID: 2199470
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):392-395.
Although complete or partial deficiency of anterior pituitary hormone is well known,but isolated TSH deficiency is relatively rare throughout the world. Hypothyroidism due to isolated TSH deficiency is diagnosed by...
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A Case of Black Adrenocortical Adenoma Causing Cushing's Syndrome with Contralateral Nonfuncioning Adenoma

Park DJ, Park KS, Nam KJ, Kim SY, Cho BY, Lee HG, Yoon YK, Oh SK

  • KMID: 2199473
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):410-417.
We report herein the case of a 38-year-old woman with Cushings syndrome caused by bilateral adrenocortical adenomas. The adrenal tumor on the left side hypersecreted cortisol and no findings of...
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A Case of Osteosarcoma induced Oncogenic Osteomalacia Detected by MRI

Lim SK, Song YD, Lee HC, Huh KB, Park KH, Kim KR, Hong SW, Nam JH, Yook JI, Choi BJ, Kim MK, Shin KH

  • KMID: 2199472
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):401-409.
Oncogenic osteomalacia is a syndrome characterized by phosphaturia, hypophosphatemia, decreased 1,25-dihydroxyvitamin D level and specific signs and symptoms of osteomalacia. It is associated with the presence of neoplasm originated from...
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Prevalence of Thyrotoxicosis and Hypothyroidism in the Subjects for Health Check-Up

Chung JH, Kim BJ, Choi YH, Shin MH, Kim SH, Min YK, Lee MS, Lee MG, Kim KW

  • KMID: 2199460
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):301-313.
BACKGROUND: The prevalence of ovat hyperthyroidism ar hypothyroidism has been estimated up to 5% in the general populatian. Subclinical hyperthyroidism and subclinical hypothyroidism have pevalences of approximately 1% and 6%,...
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Effect of Isoproterenol on the Glucose-induced Hypothalamin Somatostatin Release

Kim SW, Kim JW, Kim YS, Choi YK, Yang IM, Woo JT, Park CY, Kim SW, Ro JH, Kim SH, Oh SJ, Kim DY

  • KMID: 2199456
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):255-264.
BACKGROUND: Acute hypoglycemia stimulates somatostatin (SRIH) release from the hypothalamus, and which in turn suppress growth hormone (GH) secretion from the anterior pituitary gland. However, the exact mechanism of glucose...
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A Case of Isolated ACTH Deficiency with Rapid Deterioration

Hong SK, Lee EJ, Kim KS, Lee CR, Park HJ, Song HH, Lee YS

  • KMID: 2199471
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):396-400.
Isolated ACTH deficiency is a rare disorder, and usually characterized by its chronic course. The 59 year-old woman patient who had been healthy until 2 months ago, admitted because of...
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A Case of Diabetes Mellitus Caused by Calcitonin and Somatostatin Secreting Pancreatic Islet Tumor

Chung JH, Kim KW, Kim BJ, Kim SH, Kim KA, Lee MS, Lee MG, Min YK, Ham JR, Kim DJ, Lee HJ, Oh YR

  • KMID: 2199475
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):425-431.
A case of 39-year-old diabetic patient with a calcitonin and somatostatin secreting pancreatic islet tumor is presented. He had suffered from chronic diarrhea and dyspepsia for 10 years and was...
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Serum Leptin Levels in Patients with Thyroid Dysfunction

Song MH, Kim YK, Ro HK, Han HJ, Joo WC, Won JH, Kim Y, Kim HJ, Chae SH

  • KMID: 2199468
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):372-378.
BACKGROUND: Leptin, the product of ob gene, is an important circulating hormone for the regulation of homeostasis of body weight and enegy expenditure. There was a previous reports that thyroid...
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One Family of Familial Combined hyperlipidemia Associated with Various Metabolic Abnormalities

Lee KW, Lee SK, Chung YS, Kim HM, Kim YJ, Hong EK, Chae BN, Park JW

  • KMID: 2199474
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):418-424.
Familial combined hyperlipidemia is one af the manogenic disorders frequently found in humans and is seen in 0.5~2% of the general populatian, accounting for at least 10% of persons with...
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Endocrine Tumors of the Pancreas Secreting Multiple Hormones

Kim YC, Kwon OJ, Kim SH, Yoon YK, Oh SK

  • KMID: 2199469
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):379-391.
BACKGROUND: Endocrine pancreas tumor is a rare disease which incidence is less than 2% of all pancreatic tumors. But it comprises various types of tumor and usually secretes several hormones...
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Comparosin of Pretreatment and Postreatment Whole Body Iodine-131 Scans in Patients with Differentiated Thyroid Carcinoma

Kim ES, Song YK, Ryu JS, Moon DH

  • KMID: 2199462
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):323-329.
BACKGROUND: Whole body 131I scan is routinely performed in the postoperative evaluation of patients with differentiated thyroid carcinoma to detect recurrence and functioning metastasis. Previous reports suggested that posttreatment whole...
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A Comparison Technetium-99m and Iodine-123 Scan in Thyroid Hot Nodules

Kim ES, Hong SJ, Song YK, Ryu JS, Moon DH, Kim KS

  • KMID: 2199464
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):339-345.
BACKGROUND: Pertechnetate ( Tc) has been widely employed for thyroid imaging. While pertechnetate and radioiodide have usually similar results in identifying thyroid nodules, occasionally differences have been noted. We intended...
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Influence of Early Age at Menopause on Bone Mineral Density and Biochemical Bone Marker

Park YJ, Shin CS, Park DJ, Kim JK, Kim SY, Cho BY, Lee HG, Kim JH, Chung IK

  • KMID: 2199465
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):346-354.
BACKGROUND: Among the various factors affecting bone mass and bone metabolism, aging and menopause play a major role. After the disappearance of the menstrual cycle, estrogen deficiency is the most...
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Serum Soloble Fas in Autoimmune Thyroid Disease

Song MH, Ro HK, Han HJ, Joo WC, Shin JK, Kim HJ, Chae SH

  • KMID: 2199459
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):293-300.
The Changes of soluble Fas levels in Patients with Autoimmune Thyroid Diseases BACKGROUD: Apoptosis was observed in thyroid tissue from Hashimoto disease but not those from Graves disease. Recently Fas...
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Effect of Radioactive Iodine Therapy in Patients with Scan-Negative, Thyroglobulin-Positive Thyroid Cancer

Kim ES, Hong SJ, Kim JY, Song YK, Ryu JS, Moon DH, Kim KS, Kim SW

  • KMID: 2199463
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):330-338.
BACKGROUND: After total thyroidectomy the presence of detectable serum thyroglobulin(Tg) concentration is an index of residual or metastatic thyroid tissue and is usually well correlated with positive I whole body...
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Relationship between the Expression of Growth Hormone-Releasing Hormone Receptor Gene and Endocrinologic Profiles in GH-Secreting Pituitary Adenomas

Kim SW, Kim JW, Kim YS, Choi YK, Park SJ, Yang IM, Woo JT, Ryu MS, Park CY, Kim SW

  • KMID: 2199455
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):241-254.
BACKGROUND: Growth hormone-releasing hormone (GHRH) plays a key role in the regulation of the proliferation and differentiation of somatomammotroph cells as well as secretion of GH. The actions of GHRH...
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Allelotyping and Comparative Genomin Hybridization Studies in Papillary Thyroid Carcinomas and Follicular Adenomas

Ahn IM, Kim ES, Park HS, Park KY, Hong SJ, Gong KY, Kim JY, Kim SB, Kim SH, Lee SJ, Han JH, Jee KJ

  • KMID: 2199461
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):314-322.
BACKGROUND: In our previous study, the prevalence of the known causes of thyroid tumorigenesis was relatively rare in Korean population, suggesting genetic and environmental differences exist. Screening of genetic alteration...
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