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Therapeutic Appilication of Molecular Genetics in Psychiatry

Lee MS

  • KMID: 1834619
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):17-33.
Advances in molecular biology contribute to the understanding genetic mechanism of psychiatric disorders. They have renewed hope for the discovery of disease relevant gene. However, the results somewhat confused. And...
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The Neurophysiological Approaches in Animal Experiments

Cheon JS

  • KMID: 1834618
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):3-16.
The neurophysiological study has been widely used in search of the relationship between brain and behavior. The basic techniques for the animal experiments of this kind such as stereotaxic techniques,...
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Therapeutic Drug Monitoring(TDM) of Psychotropic Drugs

Yang BH

  • KMID: 1834622
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):56-65.
Clinicians can use therapeutic drug monitoring(TDM) to optimise dosage decisions with psychotropic drugs, in order to maximize efficacy and prevent toxicity, especially when individuals are nonresponsive to treatment or vulnerable...
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Neuropsychiatric Treatment of Patients with Traumatic Brain Injury

Jung HY

  • KMID: 1834624
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):71-82.
The neuropsychiatric sequelae of traumatic brain injury are effects on complex aspect of cognition, emotion and behavior. They include problems with attention and arousal, concentration, executive function, intellectual changes, memory...
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A Case of Risperidone-induced Neuroleptic Malignant Syndrome

Kang HY, Kim YK, Lee MS

  • KMID: 1834633
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):138-141.
Neuroleptic malignant syndrome(NMS) is an uncommon but potentially fatal idiosyncratic reaction to neuroleptics, characterized by muscular rigidity, fever, autonomic dysfunction, and altered consciousness. The major theories to explain NMS is...
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A Case of Antipsychotic-Regression Syndrome in Haloperidol Treated Tourette's Syndrome

Jeong HY, Cho HJ, Kwon YJ, Park IJ, Jin HH

  • KMID: 1834632
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):134-137.
Authors report a case of separation anxiety disorder, which developed as a side effect during haloperidol treatment of Tourette syndromes(TS). In this case, 14 years old boys developed attention deficit...
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Behavioral Toxicity of Psychotropic Drugs

Yoon JS

  • KMID: 1834621
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):46-55.
Any compound which disrupts the integrity of psychological aspects of performance, in particular, cognitive ability and psychomotor function analogous to the psychological behaviors of routine life, is known to be...
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The Relation of Onset-Age and beta-Endorphin Levels in Alcohol Dependence

Jeong HY, Park IJ, Kim JM, Jin HH

  • KMID: 1834628
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):107-113.
OBJECTIVES: To evaluate the relation of onset-age and plasma level of beta-endorphin, Ethanol, beta-endorphin, cortisol and blood glucose were compared in 48 male alcoholics and 29 normal controls. METHODS: Alcoholics are...
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The Relation of Family History and beta-Endorphin Levels in Alcohol Dependence

Jeong HY, Park IJ, Kwon YJ

  • KMID: 1834627
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):102-106.
OBJECTIVES: To evaluated the relation of familial history of alcoholism and plasma level of beta-endorphin, ethanol, beta-endorphin, cortisol and blood glucose were compared in 48 male alcoholics and 29 normal...
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A Case on Risperidone-Induced Tardive Dyskinesia

Kim HS, Kim HS, Min BK

  • KMID: 1834631
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):129-133.
OBJECTIVE: Base on clinical practice, the authors report a case of tardive dyskinesia arising during the course of treatment with resperidal. METHODS: This article was review and analysis of a case...
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Neuropeptides in Clinical Psychiatric Research : Endorphins and Cholecystokinins

Kim YH, Shin JC

  • KMID: 1834620
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):34-45.
We provide the reader with a brief introduction to the neurobiology of neuropeptides. Several comprehensive reviews of the distribution and neurochemical. neurophysiological. neuropharmacological and behavioral effects of the major neuropeptides...
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A Clinical Trial of Combined Treatment with Estrogen and Antipsychotics in Females with Chronic Schizophrenia

Kwon EJ, Kim JS, Jung IK, Lee DW

  • KMID: 1834630
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):122-128.
OBJECTIVE: This study was a open clinical trial aimed at exploring the effectiveness of combined treatment with estrogen and antipsychotics to the chronic female schizophrenics. METHOD: 40 female patients who met...
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A preliminary Study for Nonlinear Dynamic Analysis of EEG in Patients with Dementia of Alzheimer

Chae JH, Kim DJ, Choi SB, Bahk WM, Lee CT, Kim KS, Jeong JS, Kim SY

  • KMID: 1834626
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):95-101.
The changes of electroencephalogram(EEG) in patients with dementia of Alzheimer's type are most commonly studied by analyzing power or magnitude in traditionally defined frequency bands. However because of the absence...
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Alzheimer's Disease and Apoptosis

Kim YH, Kim YK, Kim SH, Lee SK, Kim SS, Kim HS, Park CH, Jeong SJ, Suh YH

  • KMID: 1834623
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):66-70.
Apoptosis is a form of cell death in which the cells shrink and exhibit nuclear chromatin condensation and DNA fragmentation, and yet maintain membrane integrity. Many lines of evidence have...
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The Effects of Coadministration of Haloperidol and Bethanechol on Plasma Haloperidol and Reduced Haloperidol Concentrations

Kim HS, Ahn JY, Yeo UT, Jo SH

  • KMID: 1834629
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):114-121.
Bethanechol, a cholinergic agonist, has been recommended for the management of peripheral anticholinergic side effects during the treatment of antipsychotic medications. But there have been few studies which have evaluated...
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Association of Schizophrenia with Pathological Aging : A Behavioral and Histological Study Using Animal Model

Cheon JS, Oh BH, Chang HI

  • KMID: 1834625
  • J Korean Soc Biol Psychiatry.
  • 1998 Jun;5(1):83-94.
OBJECTIVES: Phencyclidine(PCP) or PCP-like substances such as ketamine have been know to rekindle the cognitive dysfunction in schizophrenia. The aims of this study were to identify whether PCP-like substances can...
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