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A Recent Update of Clinical and Research Topics Concerning Adult Moyamoya Disease

Jeon JP, Kim JE

A better understanding of moyamoya disease (MMD), such as natural clinical course, surgical outcomes and research, has been obtained. This review article focuses on an giving an update for adult...
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Giant Intrathoracic Meningocele and Breast Cancer in a Neurofibromatosis Type I Patient

Malla HP, Park BJ, Koh JS, Jo DJ

Intrathoracic meningoceles are relatively rare entities found in patients with neurofibromatosis type I (NF1). Given that both the BRCA1 and NF-1 genes are located on the same long arm of...
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Spontaneous Resolution of Chronic Subdural Hematoma : Close Observation as a Treatment Strategy

Kim HC, Ko JH, Yoo DS, Lee SK

OBJECTIVE: Chronic subdural hematoma (cSDH) is common condition in neurosurgical field. It is difficult to select the treatment modality between the surgical method and the conservative method when patients have...
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Intradural Procedural Time to Assess Technical Difficulty of Superciliary Keyhole and Pterional Approaches for Unruptured Middle Cerebral Artery Aneurysms

Choi YJ, Son W, Park KS, Park J

OBJECTIVE: This study used the intradural procedural time to assess the overall technical difficulty involved in surgically clipping an unruptured middle cerebral artery (MCA) aneurysm via a pterional or superciliary...
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Multiple Spinal Revision Surgery in a Patient with Parkinson's Disease

Malla HP, Kim MK, Kim TS, Jo DJ

Parkinson's disease (PD) patients frequently have several spinal deformities leading to postural instabilities including camptocormia, myopathy-induced postural deformity, Pisa syndrome, and progressive degeneration, all of which adversely affect daily life...
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Expanded Endoscopic Transnasal Approach to the Chordoid Glioma of the Third Ventricle : The First Case Ever Reported

Zeinalizadeh M, Sadrehosseini SM, Tayebi Meybodi K, Sharifabadi AH

Chordoid glioma of the third ventricle is a rare and challenging tumor to surgery because of its unique anatomical location and its close juxtaposition to the neurovascular structures and hypothalamus....
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The Effect of Perioperative Radiation Therapy on Spinal Bone Fusion Following Spine Tumor Surgery

Kim TK, Cho W, Youn SM, Chang UK

INTRODUCTION: Perioperative irradiation is often combined with spine tumor surgery. Radiation is known to be detrimental to healing process of bone fusion. We tried to investigate bone fusion rate in...
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Surgical Outcomes of Post-Fusion Lumbar Flatback Deformity with Sagittal Imbalance

Kim JS, Kim SM

OBJECTIVES: To review surgical results of post-fusion lumbar flatback treated with pedicle subtraction osteotomy (PSO) or Smith-Petersen osteotomies (SPOs). METHODS: Twenty-eight patients underwent osteotomies. Radiological outcomes by sagittal vertical axis (SVA),...
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Analysis of Risk Factor for the Development of Chronic Subdural Hematoma in Patients with Traumatic Subdural Hygroma

Ahn JH, Jun HS, Kim JH, Oh JK, Song JH, Chang IB

OBJECTIVE: Although a high incidence of chronic subdural hematoma (CSDH) following traumatic subdural hygroma (SDG) has been reported, no study has evaluated risk factors for the development of CSDH. Therefore,...
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Temperature Distributions of the Lumbar Intervertebral Disc during Laser Annuloplasty : A Cadaveric Study

Lee MH, Kim IS, Hong JT, Sung JH, Lee SW, Kim DH

OBJECTIVE: Low back pain, caused intervertebral disc degeneration has been treated by thermal annuloplasty procedure, which is a non-surgical treatement. The theoretical backgrounds of the annuloplasty are thermal destruct of...
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Sclerosing Meningioma : Radiological and Clinical Characteristics of 21 Cases

Kang H, Kim JW, Se YB, Dho YS, Choi SH, Park SH

OBJECTIVE: A rare subtype of meningioma, sclerosing meningioma is not included in the current World Health Organization classification of meningiomas and is classified into the category of other morphological variation...
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A Comparison of Implants Used in Double Door Laminoplasty : Allogeneic Bone Spacer versus Hydroxyapatite Spacer

Lee DY, Lee CK, Kim IS

OBJECTIVE: The aim of this study was to compare the clinical and radiological outcomes associated with the use of hydroxyapatite (HA) spacer and allogeneic bone (AB) spacer in laminoplasty. METHODS: From...
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Foreign Body Reaction after Implantation of a Device for Intervertebral Assisted Motion

Seo JY, Ha KY, Kim YH, Ahn JH

The device for intervertebral assisted motion (DIAM) is a dynamic implant that consists of a silicone bumper enveloped by a polyethylene terephthalate (PET) fiber sack. Silicone and PET were used...
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Risk Factors for the Development and Progression of Atlantoaxial Subluxation in Surgically Treated Rheumatoid Arthritis Patients, Considering the Time Interval between Rheumatoid Arthritis Diagnosis and Surgery

Na MK, Chun HJ, Bak KH, Yi HJ, Ryu JI, Han MH

OBJECTIVE: Rheumatoid arthritis (RA) is a systemic disease that can affect the cervical spine, especially the atlantoaxial region. The present study evaluated the risk factors for atlantoaxial subluxation (AAS) development...
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Microsurgical Foraminotomy via Wiltse Paraspinal Approach for Foraminal or Extraforaminal Stenosis at L5-S1 Level : Risk Factor Analysis for Poor Outcome

Cho SI, Chough CK, Choi SC, Chun JY

OBJECTIVE: The purpose of this study was to present the outcome of the microsurgical foraminotomy via Wiltse paraspinal approach for foraminal or extraforaminal (FEF) stenosis at L5–S1 level. We investigated...
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Metallothinein 1E Enhances Glioma Invasion through Modulation Matrix Metalloproteinases-2 and 9 in U87MG Mouse Brain Tumor Model

Hur H, Ryu HH, Li CH, Kim IY, Jang WY, Jung S

Malignant glioma cells invading surrounding normal brain are inoperable and resistant to radio- and chemotherapy, and eventually lead to tumor regrowth. Identification of genes related to motility is important for...
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Proteomic Analysis of a Rat Cerebral Ischemic Injury Model after Human Cerebral Endothelial Cell Transplantation

Choi TM, Yun M, Lee JK, Park JT, Park MS, Kim HS

OBJECTIVE: Cerebral endothelial cells have unique biological features and are fascinating candidate cells for stroke therapy. METHODS: In order to understand the molecular mechanisms of human cerebral endothelial cell (hCMEC/D3) transplantation...
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A Clinical Analysis of Secondary Surgery in Trigeminal Neuralgia Patients Who Failed Prior Treatment

Kang IH, Park BJ, Park CK, Malla HP, Lee SH, Rhee BA

OBJECTIVE: Although many treatment modalities have been introduced for trigeminal neuralgia (TN), the long-term clinical results remain unsatisfactory. It has been particularly challenging to determine an appropriate treatment strategy for...
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Parasellar Extension Grades and Surgical Extent in Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Adenomas : A Single Surgeon's Consecutive Series with the Aspects of Reliability and Clinical Validity

Lee SH, Park JS, Lee S, Kim SW, Hong YK

OBJECTIVE: The inter-rater reliability of the modified Knosp's classification was measured before the analysis. The clinical validity of the parasellar extension grading system was evaluated by investigating the extents of...
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Retrospective Analysis of Cerebrospinal Fluid Profiles in 228 Patients with Leptomeningeal Carcinomatosis : Differences According to the Sampling Site, Symptoms, and Systemic Factors

Shim Y, Gwak HS, Kim S, Joo J, Shin SH, Yoo H

OBJECTIVE: Elevated cell counts and protein levels in cerebrospinal fluid (CSF) result from disease activity in patients with leptomeningeal carcinomatosis (LMC). Previous studies evaluated the use of CSF profiles to...
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