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A Case of Myxedema Coma Presenting as a Brain Stem Infarct in a 74-Year-Old Korean Woman

Ahn JY, Kwon HS, Ahn HC, Sohn YD

Myxedema coma is the extreme form of untreated hypothyroidism. In reality, few patients present comatose with severe myxedema. We describe a patient with myxedema coma which was initially misdiagnosed as...
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Severe Hypertriglyceridemia in Diabetic Ketoacidosis Accompanied by Acute Pancreatitis: Case Report

Hahn SJ, Park JH, Lee JH, Lee JK, Kim KA

We report a case of diabetic ketoacidosis (DKA) and hypertriglyceridemia (severely elevated to 15,240 mg/dL) complicated by acute pancreatitis, which was treated successfully with insulin therapy and conservative management. A...
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Obstructive Fibrinous Tracheal Pseudomembrane After Tracheal Intubation: A Case Report

Kang HH, Kim JW, Kang JY, Kim JS, Kim MS, Kim SS, Kim YH, Lee SH, Moon HS

Obstructive fibrinous tracheal pseudomembrane is a rare, but potentially fatal complication associated with endotracheal intubation. It has been known that the formation of tracheal pseudomembrane is related with intracuff pressure...
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A Case of Resistance to Thyroid Hormone with Thyroid Cancer

Kim HK, Kim D, Yoo EH, Lee JI, Jang HW, Tan AH, Hur KY, Kim JH, Kim KW, Chung JH, Kim SW

Resistance to thyroid hormone (RTH) is an autosomal dominant hereditary disorder that is difficult to diagnose because of its rarity and variable clinical features. The magnitude of RTH is caused...
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High Dose Vitamin D3 Attenuates the Hypocalciuric Effect of Thiazide in Hypercalciuric Rats

Jang HR, Lee JW, Kim S, Heo NJ, Lee JH, Kim HS, Jung JY, Oh YK, Na KY, Han JS, Joo KW

Thiazide is known to decrease urinary calcium excretion. We hypothesized that thiazide shows different hypocalciuric effects depending on the stimuli causing hypercalciuria. The hypocalciuric effect of hydrochlorothiazide (HCTZ) and the...
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Two Cases of Transfusion-related Acute Lung Injury Triggered by HLA and Anti-HLA Antibody Reaction

Lee JH, Kang ES, Kim DW

Transfusion-related acute lung injury (TRALI) is a serious adverse transfusion reaction that is presented as acute hypoxemia and non-cardiogenic pulmonary edema, which develops during or within 6 hr of transfusion....
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A Case of Multicentric Castleman's Disease Having Lung Lesion Successfully Treated with Humanized Anti-interleukin-6 Receptor Antibody, Tocilizumab

Higuchi T, Nakanishi , Takada K, Matsumoto , Okada M, Horikoshi , Suzuki K

This report presents the case of a patient demonstrating multicentric Castleman's disease (MCD) with a lung lesion that was successfully treated with an anti-interleukin-6 receptor antibody, tocilizumab in combination with...
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The First Korean Case of Cutaneous Lung Tissue Heterotopia

Jeon GW, Han SW, Jung JM, Kang MS, Sin JB

Cutaneous lung tissue heterotopia is a very rare disorder where mature lung tissues develop in the skin. This is only the second known report of cutaneous lung tissue heterotopia, with...
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Birth Outcomes of Koreans by Birthplace of Infants and Their Mothers, the United States versus Korea, 1995-2004

Lim JW, Lee JJ, Park CG, Sriram S, Lee KS

The acculturation effect of immigrant women on birth outcomes varies by race. We examined birth outcomes of three groups of births for the period 1995-2004, USA births to the USA-born...
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Urodynamic and Histological Changes in a Sterile Rabbit Vesicoureteral Reflux Model

Baek M, Paick SH, Jeong SJ, Hong SK, Kim SW, Choi H

This study aimed to investigate pressure changes of renal pelvis and histological change of kidneys in a surgically induced sterile rabbit vesicoureteral reflux (VUR) model. Five rabbits served as a...
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Acute Kidney Injury due to Menstruation-related Disseminated Intravascular Coagulation in an Adenomyosis Patient: A Case Report

Son J, Lee DW, Seong EY, Song SH, Lee SB, Kang J, Yang BY, Lee SJ, Choi JR, Lee KS, Kwak IS

The authors report a case of acute kidney injury (AKI) resulting from menstruation-related disseminated intravascular coagulation (DIC) in an adenomyosis patient. A 40-yr-old woman who had received gonadotropin for ovulation...
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Motor Unit Number Estimation in Evaluating Disease Progression in Patients with Amyotrophic Lateral Sclerosis

Ahn SW, Kim SH, Oh DH, Kim SM, Park KS, Hong YH, Kwon OS, Sung JJ, Lee KW

We investigated the availability of motor unit number estimation (MUNE) as a quantitative method to assess the severity and clinical progression of amyotrophic lateral sclerosis (ALS). The 143 ALS patients...
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Clinical Significance of Colonic Diverticulosis Associated with Bowel Symptoms and Colon Polyp

Lee KM, Paik CN, Chung WC, Jung SH, Chang UI, Yang JM

This study was done to evaluate prospectively the clinical significance of colonic diverticulosis. In the 1,030 consecutive outpatients undergoing colonoscopy, the information on the demographics, the patterns of bowel symptoms,...
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Warfarin-Induced Penile Necrosis in a Patient with Heparin-Induced Thrombocytopenia

Chang IH, Ha MS, Chi BH, Kown YW, Lee SJ

A 56-yr-old man with lung adenocarcinoma presented with subsegmental pulmonary thrombosis. Platelet count on presentation was 531x10(9)/L. The patient was anticoagulated with subcutaneous low molecular weight heparin (LMWH). Next day,...
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Aldosterone Modulates Cell Proliferation and Apoptosis in the Neonatal Rat Heart

Sohn HJ, Yoo KH, Jang GY, Lee JH, Choi BM, Lee JH, Bae IS, Yim HE, Son CS, Lee JW

In the present study, we investigated whether and how the mineralocorticoid receptor antagonist spironolactone affects cardiac growth and development through apoptosis and cell proliferation in the neonatal rat heart. Newborn...
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Continuity of Care for Elderly Patients with Diabetes Mellitus, Hypertension, Asthma, and Chronic Obstructive Pulmonary Disease in Korea

Hong JS, Kang HC, Kim J

We sought to assess continuity of care for elderly patients in Korea and to examine any association between continuity of care and health outcomes (hospitalization, emergency department visits, health care...
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Seroprevalence of Tissue Invading Parasitic Infections Diagnosed by ELISA in Korea

Lee MK, Hong SJ, Kim HR

Seroprevalence of the IgG antibodies for Clonorchis sinensis, Paragonimus westermani, Taenia solium metacestode (cysticercus), and Spirometra erinacei plerocercoid (sparganum) was measured using enzyme-linked immunosorbent assay (ELISA) in sera of patients...
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Genetic Analyses of the Chimeric CYP11B1/CYP11B2 Gene in a Korean Family with Glucocorticoid-Remediable Aldosteronism

Lee IS, Kim SY, Jang HW, Kim MK, Lee JH, Lee YH, Jo YS

Glucocorticoid-remediable aldosteronism (GRA) is an autosomal-dominant inheritable form of hyperaldosteronism with early onset hypertension. GRA is caused by unequal crossing-over of the steroid 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) genes....
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Stress-induced Alterations in Mast Cell Numbers and Proteinase-activated Receptor-2 Expression of the Colon: Role of Corticotrophin-releasing Factor

Kim DH, Cho YJ, Kim JH, Kim YB, Lee KJ

This study was performed in order to assess whether acute stress can increase mast cell and enterochromaffin (EC) cell numbers, and proteinase-activated receptor-2 (PAR2) expression in the rat colon. In...
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Differences in Clinical Characteristics between Patients with Non-Erosive Reflux Disease and Erosive Esophagitis in Korea

Ha NR, Lee HL, Lee OY, Yoon BC, Choi HS, Hahm JS, Ahn YH, Koh DH

Gastroesophageal reflux disease (GERD) is caused by abnormal reflux of gastric contents into the esophagus. GERD can be divided into two groups, erosive esophagitis and non-erosive reflux disease (NERD). The...
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