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Stages of Institutional Review Board Activities

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Infravesical Obstruction Due to Benign Intraurethral Prostatic Cyst

Chang SG, Hwang IC, Lee JH, Park YK, Lim JW

We report a case of symptomatic intraurethral prostatic cyst in a 42-yr-old man without clinical evidence of benign prostatic hyperplasia. The intraurethral cyst makes it unique from the all previously...
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Electrical Injury As A Possible Cause of Sick Sinus Syndrome

Kose S, Iyisoy A, Kursaklioglu H, Demirtas E

Electrical injury is a serious public health problem. Heart is one of the most frequently affected organs. Electrical injury can cause life-threatening cardiac complications such as asystole, ventricular fibrillation, and...
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Conn's Syndrome Associated with Behcet's Disease

Lee SS, Kim YA

A 39-yr-old woman, who had been treated for Behcet's disease for 4 yr, was admitted for further investigation of recently identified hypokalemia and hypertension. Suppressed plasma renin activity with elevated...
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Tubular Aggregate Myopathy: A Case Report

Suh YL, Kim NR

We report a first Korean case of presumably dominantly inherited primary tubular aggregate myopathy in a 19-yr-old man, who presented with slowly progressive proximal muscle stiffness and weakness. In hematoxylin...
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Cervical Epidural Abscess Secondary to Aorto-Duodenal Fistula: A Case Report

Yi HJ, Oh SH, Kwon OJ, Kim H

Although cervical epidural abscess is rare, it should be strongly suspected in any patient with unexplainable neck pain and fever, especially when the patient has a predisposing factor for this...
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Parental Concerns on the Circumcision for Elementary School Boys: A Questionnaire Study

Lee SD, Park E, Choe BM

To evaluate the parental concerns for elementary school boys (7-12 yr) on the circumcision, a randomly selected cross-sectional survey was performed in each elementary school from 16 urban wards in...
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Survey and Validation of the Criteria for Behcet's Disease Recently Used in Korea: a Suggestion for Modification of the International Study Group Criteria

Chang HK, Kim SY

The criteria employed for Korean Behcet's disease (BD) from January 1990 to December 2000 have been investigated, and the diagnostic validity for those criteria was determined. For the generation of...
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Recently Occurring Adult Tetanus in Korea: Emphasis on Immunization and Awareness of Tetanus

Shin DH, Yu HS, Park JH, Shin JH, Kim SJ

Since a nationwide childhood vaccination with tetanus toxoid, tetanus has become a rare disease in Korea. However, we recently experienced 17 cases of adult tetanus in a university hospital during...
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Nicardipine Augments Local Myocardial Perfusion after Coronary Artery Reperfusion in Dogs

Jang YH, Kim JM

Nicardipine is a potent coronary and systemic vasodilator without depression of ventricular function. We investigated the changes in local myocardial perfusion (LMP) according to the nicardipine administration after coronary reperfusion...
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Successful Combination Therapy of Cyclosporine and Methotrexate for Refractory Polymyositis with Anti-Jo-1 Antibody: A Case Report

Chang HK, Lee DH

Although corticosteroids have been the initial agent for the treatment of inflammatory myopathies (IM), immunosuppressive agents such as azathioprine, methotrexate, cyclophosphamide, or cyclosporine are commonly required to control the disease...
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Extraskeletal Osteochondroma of the Buttock

Lim SC, Kim YS, Kim YS, Moon YR

Osteochondromas are common and typically arise from the metaphyseal ends of long bones. An osteochondral neoplasm of the soft tissue, which is a lesion of uncertain pathogenesis, is uncommon and...
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A Novel Mutation (C67Y) in the NOTCH3 Gene in a Korean CADASIL Patient

Na DL, Moon SY, Kim HY, Seok JI, Kwon JC, Ki CS, Kim JW, Suh YL

We report a 52-yr-old Korean woman with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) whose diagnosis was confirmed by skin biopsy and the presence of a novel...
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No Changing Trends in Incidence of Gastric Cardia Cancer in Korea

Lee JY, Kim HY, Kim KH, Jang HJ, Kim JB, Lee JH, Kim DJ, Kim YB, Kim WJ, Yoo JY

Although there is a controversy, several reports have shown that gastric cardia cancer has tended upwards in recent years. The aim of this study was to investigate the changing trend...
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Anti-Heparin-Platelet Factor 4 Antibody is a Risk Factor for Vascular Access Obstruction in Patients Undergoing Hemodialysis

Lee EY, Hwang KY, Yang JO, Hong SY

Since heparin is an anticoagulant commonly used in hemodialysis and the patients on hemodialysis are repeatedly exposed to heparin, heparin may be the cause of the development of heparin-dependent antibodies...
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Comparison of Transepidermal Water Loss, Capacitance and pH Values in the Skin between Intrinsic and Extrinsic Atopic Dermatitis Patients

Choi SJ, Song MG, Sung WT, Lee DY, Lee JH, Lee ES, Yang JM

Atopic dermatitis (AD), with the prevalence rate of around 10 to 15%, is characterized by an intensely pruritic skin lesions with typical distribution and morphology. Recently, AD is divided into...
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Heterozygous Mutations of The Gene for Kir 1.1 (ROMK) in Antenatal Bartter Syndrome Presenting with Transient Hyperkalemia, Evolving to a Benign Course

Cho JT, Guay-Woodford LM

Bartter-like syndrome encompasses a set of inherited renal tubular disorders associated with hypokalemic metabolic alkalosis, renal salt wasting, hyperreninemic hyperaldosteronism, and normal blood pressure. Antenatal Bartter syndrome, a subtype of...
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Clinical Usefulness of the Two-site Semmes-Weinstein Monofilament Test for Detecting Diabetic Peripheral Neuropathy

Kim YJ, Kim HH, Choi SH, Park YS, Lee SY, Cho BM

The present study was done to validate the two-site Semmes-Weinstein (SW) monofilament test in identifying patients at risk of lower-extremity complications in clinical setting. The SW monofilament test and nerve...
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Partial Trisomy 2q(2q37.3->qter)and Monosomy 7q(7q34->qter) Due to Paternal Reciprocal Translocation 2;7: A Case Report

Lee YH, Ahn JM, Koo DH, Kwon KW, Lee YK, Lee HH, Nam KH, Lee KH

We report an unbalanced translocation involving chromosome 2 and 7 due to a balanced reciprocal translocation 2;7 in the father. The female fetus had a partial trisomy of the long...
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Current Status of the Institutional Review Boards in Korea: Constitution, Operation, and Policy for Protection of Human Research Participants

Kim OJ, Park BJ, Sohn DR, Lee SM, Shin SG

The institutional review board is crucial to ensure the scientific and ethical quality of human participant research. This paper analyzes a survey on the current constitution and operation of institutional...
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