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FOREWORD

Chi JG

No abstract available.
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Hong WS, Chung MH, Yun TK

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Study on Chemoprevention of Hepatocellular Carcinoma by Ginseng: An Introduction to the Protocol

The Ginseng-HCC Chemopreventive Study Osaka Group

In patients with chronic hepatitis C virus disease, there is a high incidence of development of hepatocedllular carcinaoma (HCC) in the process of transition from chronic hepatitis to hepatic cirrhosis....
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Brief Introduction of Panax ginseng C.A. Meyer

Yun TK

For many many thousand years, mankind has been using various plants as nutrient, beverage, cosmetics, dye and medicine to maintain health and to improve quality of life. In Aisa, particularly,...
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Inhibition by Ginseng of Colon Carcinogenesis in Rats

Fukushima , Wanibuchi , Li W

The inhibitory effects of ginseng on the development of 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in the colon were investigated in rats. Male, 6-week-old rats were injected with DMH once...
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Anticarcinogenic Effect of Red Ginseng on the Development of Liver Cancer Induced by Diethylnitrosamine in Rats

Wu XG, Zhu DH, Li X

Anticarcinogenic effect of red ginseng (Panax ginseng C.A. Meyer cultivated in JiLin, China) on the development of liver cancer induced by diethylnitrosamine (DEN) in rats was studied, especially in preventive...
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American Ginseng Transcriptionally Activates p21 mRNA in Breast Cancer Cell Lines

Duda RB, Kang SS, Archer SY, Meng S, Hodin RA

American ginseng (AG) has been demonstrated to inhibit breast cancer cell growth in vitro. p21 protein, a universal cell cycle inhibitor, binds cyclin-CDK complexes, an important mechanism in cell cycle...
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Colon Cancer Chemoprevention With Ginseng and Other Botanicals

Wargovich

Colorectal cancer is becoming increasingly common in Asian countries and still remains the second leading cause of cancer deaths in the United States. Efforts to prevent colon cancer have targeted...
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Chemistry and Cancer Preventing Activities of Ginseng Saponins and Some Related Triterpenoid Compounds

Shibata S

More than 25 dammarane-type tetracyclic triterpenoid saponins have been isolated from ginseng, the root and rhizome of Panax ginseng C.A. Meyer (Araliaceae). The genuine sapogenins of those saponins, 20(S)-protopanaxa-diol and...
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Cancer Chemoprevention by Ginseng in Mouse Liver and Other Organs

Nishino H, Tokuda H, Ii T, Takemura M, Kuchide M, Kanazawa M, Mou XY, Bu P, Takayasu J, Onozuka M, Masuda M, Satomi Y, Konoshima , Kishi N, Baba M, Okada Y, Okuyama T

Oral administration of red ginseng extracts (1% in diet for 40 weeks) resulted in the significant suppression of spontaneous liver tumor formation in C3H/He male mice. Average number of tumors...
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Molecular Mechanisms Underlying Anti-Tumor Promoting Activities of Heat-Processed Panax ginseng C.A. Meyer

Surh YJ, Na HK, Lee JY, Keum YS

Recently, there have been considerable efforts to search for naturally occurring substances that can inhibit, reverse, or retard the multi-stage carcinogenesis. A wide array of phenolic substances derived from edible...
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Anticarcinogenic Effect of Panax ginseng C.A. Meyer and Identification of Active Compounds

Yun TK, Lee YS, Lee YH, Kim SI, Yun HY

The failure to improve the five-year survival rate of cancer patients, from one in three in the 1960s to one in two in the 1970s, stimulated awareness of the importance...
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Epidemiological Study on Cancer Prevention by Ginseng: Are All Kinds of Cancers Preventable by Ginseng?

Yun TK, Choi SY, Yun HY

In the light of experimental results, two case-control studies and one cohort study in a population of ginseng cultivation area were conducted to confirm whether ginseng has any anticarcinogenic effect...
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Chemoprevention of Mammary, Cervix and Nervous system Carcinogenesis in Animals using Cultured Panax ginseng Drugs and Preliminary Clinical Trials in Patients with Precancerous Lesions of the Esophagus and Endometrium

Bespalov V, Alexandrov VA, Limarenko , Voytenkov , Okulov VB, Kabulov MK, Peresunko , Slepyan LI, Davydov VV

The anticarcinogenic effects and mechanisms of the biotechnological drugs of Panax ginseng C.A. Meyer cultivated in Russia, bioginseng, panaxel and panaxel- 5, were studied. Bioginseng was produced from a tissue...
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