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Suppression of NF-kappaB activation in normal T cells by supernatant fluid from human renal cell carcinomas

Kim HJ, Park JK, Kim YG

T lymphocytes from patients with renal cell carcinoma (RCC) show reduced immune function and impaired activation of the transcription factor, NF-kappaB. We determined the mechanism of NF-kappaB suppression in T...
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Solid mesenchymal hamartoma of the liver in adult

Chung JH, Cho KJ, Choi DW, Lee BH, Chi JG

This paper presents an unusual solid mesenchymal hamartoma of the liver (MHL) in adult. A well defined solid mass in the left lobe of the liver was found in a 57-year-old female....
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Gliosarcoma: a case with unusual epithelial feature

Kim DS, Kang SK, Chi JG

Astrocytic tumors, particularly gliosarcoma, may contain epithelial features in the form of trabecular, adenoid, papillary arrangement, and squamous metaplasia. A case of gliosarcoma with unusual epithelial feature is described. The patient was a...
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Endobronchial actinomycosis simulating endobronchial tuberculosis: a case report

Lee SH, Shim JJ, Kang EY, Lee SY, Jo JY, In KH, Yoo SH, Kang KH

We report a case of a 70-year-old woman who presented with mild exertional dyspnea and cough. Fiberoptic bronchoscopic findings revealed an endobronchial polypoid lesion with stenotic bronchus. The lesion was...
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Intrapulmonary and gastric teratoma : report of two cases

Joo M, Kang YK, Lee HK, Lee HS, Yum HK, Bang SW, Cho HJ

The lung and stomach are very unusual sites for teratoma. The histologic findings of intrapulmonary and gastric teratomas are not different from those arising in usual sites, such as the ovary or...
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Gallstone formation and gallbladder mucosal changes in mice fed a lithogenic diet

Chang HJ, Suh JI, Kwon SY

To investigate the pathologic change of gallbladder mucosa related to gallstone formation, 52 mice were fed a lithogenic diet containing 1% cholesterol and 0.5% cholic acid and we evaluated the...
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Erdheim-Chester disease: a case report

Park YK, Ryu KN, Huh B, Kim JD

A 42-year-old man with Erdheim-Chester disease (EC) is presented. This is the first case of this disease reported in Korea. The patient complained of knee pain and plain roentgenogram of the bilateral...
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Reflux esophagitis and its relationship to hiatal hernia

Yeom JS, Park HJ, Cho JS, Lee SI, Park IS

We performed this study to evaluate the prevalence of reflux esophagitis and/or hiatal hernia in patients referred to a medical center and to examine the relationship between endoscopic reflux esophagitis...
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Rheumatoid arthritis associated with myelodysplastic syndrome: a case report

Nam EJ, Kang YM, Kang HR, Kim JH, Rho HJ, Lee MK, Hyun SH, Kim GW, Lee JM, Kim NS

Myelodysplastic syndromes (MDS) are a group of refractory anemias resulting from a clonal stem cell disorder often associated with cytogenetic abnormalities. There is increasing recognition of immunological abnormalities in patients with MDS, including...
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Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma

Kim TS, Kim YB

Matrix metalloproteinases-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9), which degrade extracellular matrix, are believed to play a crucial role in tumor invasion and metastasis. Angiogenesis is also perceived as an important...
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A pathologic study of abdominal lymphangiomas

Chung JH, Suh YL, Park IA, Jang JJ, Chi JG, Kim YI, Kim WH

Abdominal lymphangiomas are uncommon angiomatous tumor occurring mainly in childhood. This is a retrospective clinicopathologic study of 17 cases of abdominal lymphangioma. The patients included are five children and 12...
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Air pollution and daily mortality in Inchon, Korea

Hong YC, Leem JH, Ha EH

The association between total daily mortality and air pollution was investigated for a 1-year period (January 1995 to December 1995) in Inchon, Korea. The purpose of this study was to...
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The effects of peripheral leukocytes on the hippocampal neuronal changes in transient global ischemia and unilateral cerebral hemispheric infarction

Lee HW, Koo H, Choi KG, Park KD, Lee BC

The participation of activated leukocytes and subsequent production of chemical mediators has been well accepted in the pathophysiology of hypoxic-ischemic injury. This study was performed to see the effects of...
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Four cases of therapy-related leukemia

Hur M, Lee DS, Shin HY, Ahn HS, Kim BK, Cho HI

Combination chemotherapy and radiation therapy have contributed to the successful treatment of various cancer patients. But the development of second malignancies is an inevitable complication of long-term cytotoxic treatment. The most serious and...
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Sclerosing Mucoepidermoid carcinoma with eosinophilia of the thyroid glands: a case report with clinical manifestation of recurrent neck mass

Chung J, Lee SK, Gong G, Kang DY, Park JH, Kim SB, Ro JY

Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) is a recently recognized malignant neoplasm of the thyroid gland. About 14 cases of SMECE have been reported and this is the first reported case in...
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Non-typhoid Salmonella meningitis complicated by a infarction of basal ganglia

Kim H, Jeoung JY, Ham SY, Kim SR

A previously healthy 16-month-old Korean girl with symptoms of fever, vomiting, and generalized tonic seizure was diagnosed to have Group D non-typhoid Salmonella meningitis. The patient was treated with ceftriaxone (100 mg/kg/day) and...
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Time-dependent expression of ICAM-1 & VCAM-1 on coronaries of the heterotopically transplanted mouse heart

Lee JR, Huh JH, Seo JW, Suk CJ, Jeong HM, Kim EK

To investigate the pathogenesis of accelerated graft atherosclerosis after rdiac transplantation, a genetically well-defined and reproducible animal del is required. We performed heterotopic intraabdominal heart transplantation tween the two inbred...
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Crescentic glomerulonephritis: a clinicopathologic analysis of 17 cases with emphasis on glomerular and interstitial neutrophil infiltration

Suh KS, Kim BK, Kim KH

In order to determine the extent to which specific forms of glomerulonephritis (GN) contribute to the pool of crescentic GN, renal tissues from 17 crescentic GN patients were examined with...
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Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis

Jue DM, Jeon KI, Jeong JY

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by persistent joint swelling and progressive destruction of cartilage and bone. Current RA treatments are largely empirical in origin and their...
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Adenovirus-mediated p53 tumor suppressor gene therapy against subcutaneous HuH7 hepatoma cell line nodule of nude mice

Choi JY, Park YM, Byun BH, Kim BS, Hong EG, Shin DY, Seong YR, Im DS

Mutations of the tumor-suppressor gene p53 have been found in 30-50% cases of hepatocellular carcinoma (HCC). In this study, E1-negative adenoviral vector encoding wild-type p53 under the control of the...
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