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PURPOSE: In mesial temporal lobe epilepsy (TLE). Hippocampl sclerosis (HS) is a pathologic substrate and characterized by significant neuronal loss and band-like synaptic reorganization in dentate inner molecular layer (DGIML)...
PURPOSE: Determination of medical intractability is primarily essential for planning a surgical treatment of epolepsy. Questions regarding intractability include the optimum duration of adequate antiepileptic drug (AED) treatment and the...
PURPOSE: The purpose of theis study was to identify meuropsychological features in traumatic brain injured (TBI) group and temporal lobe epileptic (TLE) group.
METHODS: Subjects were administered neuropsychological tests: the...
PURPOSE AND BACKGROUND: Zonisamide(ZNS) is a broad-spectrum antiepileptic drug (AED) effective as an adjunctive therapy for medically ingractable epilepsies. Past clinical experiences of ZNS in Korea have indicated that ZNS...
BACKGROUND: Various neuronal and glial factors which participate in neural differentiation, including neural cell adhesion molecule (NCAM), are upregulated in pathogenesis of temporal lobe epilesy (TLE).This study aimed to investigate...
BACKGROUND:Acute seizures that increase neuronal activity cause a rapid and transient induction of the immmediate early c-fos in specific brain regions. C-fos gene may mediate long-term changes in cell function,...