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A Comparison Study of Biological Behavior between Primary Tumor and Metastatic Lesions of Lymph Nodes in Breast Cancer

Cho HJ, Yoon JH, Jaegal YJ

PURPOSE: Despite the fact that the primary factor to determine the prognosis of breast cancer is the metastatic lesion rather than the primary tumor, most studies concerning the prognostic factors...
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Clinicopathologic Significance of p53 and c-erbB-2 Protein Expression in Breast Carcinoma

Kim JK, Song YJ, Cho SI, Ryu DH, Yun HY, Sung RH

PURPOSE: Reliable prognostic factors, including clinicopathological parameters (Ed-alternatively, "Reliable clinicopathologic prognostic factors") such as tumor size, axillary lymph node involvement, histologic grade, menopausal patient status and steroid receptor status, are...
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Distribution and Prognostic Effect on Adjuvant Hormone Therapy of Body Mass Index (BMI) in Korean Breast Cancer Patients

Min YK, Park CM, Kim WB, Cho SJ, Kim A, Kim NR, Cho MY, Jung SI, Bae JW, Koo BH

PURPOSE: Obesity has been shown to have important effects related to breast cancer. But there have been few data available on the distribution of body mass index (BMI) among Korean...
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Diagnosis of Palpable Breast Masses by the Modified Triple Test Score: A prospective study

Kim BS, Kim JK, Cho SI, Ryu D, Yun HY, Song YJ

PURPOSE: The modified triple test (MTT; physical examination, ultrasonography, and fine-needle aspiration cytology) for palpable breast masses yielded 100% diagnostic accuracy when all 3 components were concordant (all benign or...
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Experiences with Sentinel Lymphadenectomy in 157 Cases of Breast Carcinoma

Choi JW, Lee HD, Park BW, Jung WH, Oh KK, Ryu YH

PURPOSE: The status of the axillary nodes in breast carcinoma patients is one of the most significant prognostic factors. Although many trials in order to gain information concerning axillary status,...
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The Detection of Micrometastasis in RT-PCR Using Multiple Primers in Peripheral Blood and Bone Marrow of Breast Cancer Patients

Kim JS, Shin JS, Kim KH, Ahn CH, Park WC, Oh SJ, Jeon HM, Jung SS, Lim KW

PURPOSE: The detection of occult micrometastasis in breast cancer patients may allow the establishment of prognosis and development of new therapeutic approaches. This study was performed in order to improve...
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Chemosensitivity Test in Human Breast Cancer

Park YJ, Ryu JW

PURPOSE: Breast cancer ranks as the second most frequent cancer in women in Korea, and the rate is gradually increasing. Compared to European countries and USA., the Korean breast cancer...
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Implications of the Activation of Matrix Metalloproteinase-2 (MMP-2) on the Metastasis in Breast Cancer

Hong MK, Cho KY, Oh SJ, Kim KM, Yu SJ, Jung SS

PURPOSE: The expression of matrix metalloproteinase-2 (MMP- 2) by cancer cells has been implicated in metastasis through cancer cell invasion of the basement membranes mediated by a degradation of collagen...
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A Breast Cancer in Premenopausal Women: Pathologic Findings and an Analysis of Prognostic Factor

Lee SD, Kim JH, Song JY, Nam SJ, Yang JH, Ko YH

PURPOSE: The relationship between menopausal status at diagnosis and the prognosis in breast carcinoma remains uncertain. However, it is widely considered that breast cancer in young women is more lethal...
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Characteristics of Breast Cancer in Women Undergoing Hormone Replacement Therapy

Hur MH, Lee HK, Kang SS, Lee KS, Cho BJ, Lee SK, Lee JH

PURPOSE: Hormone replacement therapy (HRT) has been associated with an increased risk for breast cancer. Cancers in women who undergo HRT are often less advanced, and a lower mortality has...
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Cyclin D1 Expression in Primary Breast Carcinoma: Correlation with Estrogen Receptor Status and Other Clinicopathologic Parameters

Seo HC, Kim SI, Yang WI, Park CH, Park CJ

PURPOSE: Cyclins are groups of proteins that play a role as a major regulator of the G1 restriction point promoting inactivation of the retinoblastoma protein. The cyclin D1 gene, CCND1,...
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