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Closing the gap for cervical cancer research in Vietnam: current perspectives and future opportunities: a report from the 5th Gynecologic Cancer InterGroup (GCIG) Cervical Cancer Research Network (CCRN) Education Symposium

Phan NT, Tran QT, Nguyen NP, Nguyen HT, Tran LD, Pham VC, Bennett K, Chávez-Blanco A, Plante M, Suh DH, Nout R, Tan DS

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The 1st annual meeting of the East Asian Gynecologic Oncology Trial Group (EAGOT)

Yoshihara K, Lee SW, Kim YM, Enomoto T

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East Asian Gynecologic Oncology Trial Group (EAGOT): founding history and future perspective

Enomoto T, Okamoto A, Kim JH, Lai CH, Wu X, Kim YM

Racial and regional differences exist in morbidity, histology, drug response, toxicity, and prognosis of gynecologic cancer. However, most large-scale phase III studies have been conducted in Western countries, and these...
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Retraction: Circ_0075960 targets the miR-202-5p/CTNND1 axis to promote the growth and migration of endometrial carcinoma cells via regulating Wnt/β-catenin signaling activity

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Effect of continuous post-operative lidocaine infusion in an enhanced recovery program on opioid use following gynecologic oncology surgery

Taiym D, Cowan M, Nakamura B, Azad H, Strohl A, Barber E

Objective To determine the effectiveness of implementing an Enhanced Recovery After Surgery (ERAS) program, including continuous intraoperative and postoperative intravenous (IV) lidocaine infusion, on perioperative opioid use. Methods This was a single-institution retrospective...
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An overview of the current debate between using minimally invasive surgery versus laparotomy for interval cytoreductive surgery in epithelial ovarian cancer

Finch L, Chi DS

The standard of care for treatment of advanced-stage epithelial ovarian cancer is primarily surgery followed by platinum-based chemotherapy, with the operative goal to achieve complete gross resection. Cytoreductive surgeries for...
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RAIDS atlas of significant genetic and protein biomarkers in cervical cancer

Scholl S, Roufai DB, Chérif LL, Kamal M

Loss of function in epigenetic acting genes together with driver alterations in the PIK3CA pathway have been shown significantly associated with poor outcome in cervical squamous cell cancer. More recently,...
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A comparison of concurrent chemoradiotherapy and radical surgery in patients with specific locally advanced cervical cancer (stage IB3, IIA2, IIICr): trial protocol for a randomized controlled study (C-CRAL trial)

Qiu J, Sun S, Liu Q, Fu J, Huang Y, Hua K

Background At present, clinical dilemma remains to be solved in terms of therapy-choices for specific locally advanced cervical cancer (LACC) patients: 1) Although concurrent chemoradiotherapy (CCRT) is recommended as the first...
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Controversies in the treatment of advanced ovarian cancer in the PARP inhibitors era: a Delphi consensus

Redondo A, Barretina P, Pérez-Fidalgo A, Rubio MJ, González-Martín A

Objective Our aim was to reach a consensus on the management of the most controversial issues of advanced ovarian cancer. Methods Nominal group and Delphi techniques were used. A steering committee of 5...
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Real-world efficacy and safety of bevacizumab single-maintenance therapy following platinum-paclitaxel chemotherapy plus bevacizumab in patients with advanced cervical cancer

Kotaka S, Kondo E, Kawai Y, Okamoto K, Kishigami Y, Yamawaki T, Nagao K, Hirata T, Suzuki S

Objective Bevacizumab maintenance therapy following platinum-based combination chemotherapy for metastatic, recurrent, or persistent cervical cancer is not recommended as standard therapy. This pilot study aimed to evaluate the efficacy and safety...
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FIGO staging of endometrial cancer: 2023

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N, Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee

Introduction Many advances in the understanding of the pathologic and molecular features of endometrial cancer have occurred since the FIGO staging was last updated in 2009. Substantially more outcome and biological...
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Laparoscopic radical hysterectomy without uterine manipulator or vaginal tube use

Yang EJ, Lee AJ, So KA, Lee SJ, Kim TJ, Shim SH

In the Laparoscopic Approach to Cervical Cancer trial, minimally invasive surgery (MIS) has been associated with significantly lower disease-free survival and overall survival rates. The proposed reasons for the increased...
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Diverse genetic spectrum among patients who met the criteria of hereditary breast, ovarian and pancreatic cancer syndrome

Lin PH, Tien YW, Cheng WF, Chiang YC, Wu CH, Yang K, Huang CS

Objective Genetic high-risk assessment combines hereditary breast, ovarian and pancreatic cancer into one syndrome. However, there is a lack of data for comparing the germline mutational spectrum of the cancer predisposing...
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Surgical technique of two-step pelvic and para-aortic sentinel lymph node mapping in early-stage endometrial cancer: laparoscopic, robotic, and open method

Cho YJ, Park JY

Since sentinel lymph node mapping in endometrial cancer is becoming more widely used, the need of standardizing surgical technique is growing [1, 2]. The objective of this surgical video is...
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AP2α negatively regulates PDHA1 in cervical cancer cells to promote aggressive features and aerobic glycolysis in vitro and in vivo

Zhao L, Geng R, Huang Y, Zhang J, Cheng H, Zhou C, Wang Y

Objective As a gate-keeper enzyme link, pyruvate dehydrogenase E1 subunit alpha (PDHA1) functions as a key regulator during glycolysis and the mitochondrial citric acid cycle, which has been reported in several...
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Anti-cancer effect of fenbendazole-incorporated PLGA nanoparticles in ovarian cancer

Chang CS, Ryu JY, Choi JK, Cho YJ, Choi JJ, Hwang JR, Choi JY, Noh JJ, Lee CM, Won JE, Han HD, Lee JW

Objective Fenbendazole (FZ) has potential anti-cancer effects, but its poor water solubility limits its use for cancer therapy. In this study, we investigated the anti-cancer effect of FZ with different drug...
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