- An attempt to establish real-world databases of poly(ADP-ribose) polymerase inhibitors for advanced or recurrent epithelial ovarian cancer: the Japanese Gynecologic Oncology Group
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Shimada M, Yoshihara K, Tanigawa T, Nomura H, Hamanishi J, Fujiwara S, Tanabe H, Kajiyama H, Mandai M, Aoki D, Enomoto T, Okamoto A
- KMID: 2552567
- J Gynecol Oncol.
- 2023 May;34(3):e62.
- doi: 10.3802/jgo.2023.34.e62
The development of new treatments for gynecological malignancies has been conducted mainly through collaborative international phase III trials led by the United States and Europe. The survival outcomes of many... -
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- A prospective randomized multicenter trial for lymphadenectomy in early-stage ovarian cancer: LOVE study
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Deng T, Liu K, Chen L, Chen X, Li HW, Guo H, Zhang H, Xiang L, Feng X, Wang X, Ngan HY, Zhao J, Zou D, Liu Q, Liu J
- KMID: 2552565
- J Gynecol Oncol.
- 2023 May;34(3):e52.
- doi: 10.3802/jgo.2023.34.e52
Background The Lymphadenectomy in Ovarian Neoplasms (LION) study revealed that systemic lymphadenectomy did not bring survival benefit for advanced ovarian cancer patients with clinically normal lymph nodes and was associated with... -
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- The value of PET/CT for cytoreductive surgery selection in recurrent ovarian carcinoma
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Nunes RL, Teixeira FR, Diniz TP, Faloppa CC, Mantoan H, Costa AABAd, Baiocchi G
- KMID: 2552562
- J Gynecol Oncol.
- 2023 May;34(3):e31.
- doi: 10.3802/jgo.2023.34.e31
Objective To evaluate the value of positron emission tomography/computed tomography (PET/CT) in predicting no residual disease (NRD) after secondary cytoreductive surgery (SCS) compared with MSK criteria, the iMODEL, and the AGO... -
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- Trends and characteristics of fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer in Japan: a survey by the Gynecologic Oncology Committee of the Japan Society of Obstetrics and Gynecology
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Ushijima K, Tsuda N, Yamagami W, Mitsuhashi A, Mikami M, Yaegashi N, Enomoto T
- KMID: 2552555
- J Gynecol Oncol.
- 2023 May;34(3):e38.
- doi: 10.3802/jgo.2023.34.e38
Objective The objective of this study was to examine the current trends in fertility-sparing (FS) treatment for young atypical endometrial hyperplasia (AEH) and endometrial cancer (EC) patients in Japan. Methods This study was... -
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- Transvaginal cervical tumor-concealing no-look no-touch technique in minimally invasive radical hysterectomy for early-stage cervical cancer: a novel operation technique
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Kanao H, Fusegi A, Omi M, Youssefzadeh AC, Nomura H, Matsuo K
- KMID: 2552564
- J Gynecol Oncol.
- 2023 May;34(3):e27.
- doi: 10.3802/jgo.2023.34.e27
The Laparoscopic Approach to Cervical Cancer (LACC) trial demonstrated that minimally invasive radical hysterectomy was inferior to the open approach [1]; this unexpected result could be attributed to the spillage... -
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- Efficacy of lymph node dissection on stage IIICr of cervical cancer before CCRT: study protocol for a phase III, randomized controlled clinical trial (CQGOG0103)
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He M, Guo M, Zhou Q, Tang Y, Zhong L, Liu Q, Fan X, Zhao X, Zhang X, Chen G, Shen Y, Xu Q, Chen X, Li Y, Zou D
- KMID: 2552566
- J Gynecol Oncol.
- 2023 May;34(3):e55.
- doi: 10.3802/jgo.2023.34.e55
Background Cervical cancer is still present a major public health problem, especially in developing countries. In International Federation of Gynaecology and Obstetrics 2018, allowing assessment of retroperitoneal lymph nodes by imaging... -
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- Phase I/II prospective clinical trial for the hybrid of intracavitary and interstitial brachytherapy for locally advanced uterine cervical cancer
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Murakami N, Watanabe M, Uno T, Sekii S, Tsujino K, Kasamatsu T, Machitori Y, Aoshika T, Kato S, Hirowatari H, Kaneyasu Y, Nakagawa T, Ikushima H, Ando K, Murata M, Yoshida K, Yoshioka H, Murata K, Ohno T, Okonogi N, Saito AI, Ichikawa M, Okuda T, Tsuchida K, Sakurai H, Yoshimura R, Yoshioka Y, Yorozu A, Kunitake N, Okamoto H, Inaba K, Kato T, Igaki H, Itami J
- KMID: 2552558
- J Gynecol Oncol.
- 2023 May;34(3):e24.
- doi: 10.3802/jgo.2023.34.e24
Objective The purposes of this trial were to demonstrate the feasibility and effectiveness of the hybrid of intracavitary and interstitial brachytherapy (HBT) for locally advanced cervical cancer patients in the phase... -
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- Trend and characteristics of minimally invasive surgery for patients with endometrial cancer in Japan
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Yoshida H, Machida H, Matsuo K, Terai Y, Fujii T, Mandai M, Kawana K, Kobayashi H, Mikami M, Nagase S
- KMID: 2552557
- J Gynecol Oncol.
- 2023 May;34(3):e56.
- doi: 10.3802/jgo.2023.34.e56
Objective Owing to the potential benefits of minimally invasive hysterectomy for endometrial cancer, the practice pattern has recently shifted in Japan. This study examined the trends in minimally invasive surgery (MIS)... -
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- Preoperative serum microRNAs as potential prognostic biomarkers in ovarian clear cell carcinoma
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Suzuki K, Yokoi A, Yoshida K, Kato T, Ochiya T, Yamamoto Y, Kajiyama H
- KMID: 2552563
- J Gynecol Oncol.
- 2023 May;34(3):e34.
- doi: 10.3802/jgo.2023.34.e34
Objective Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian carcinoma with poor prognosis. However, no effective biomarkers have been established for predicting unfavorable events, including recurrence and poor... -
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- Risk factors for lower extremity lymphedema after surgery in cervical and endometrial cancer
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Lee J, Byun HK, Im SH, Son WJ, Roh YH, Kim YB
- KMID: 2552554
- J Gynecol Oncol.
- 2023 May;34(3):e28.
- doi: 10.3802/jgo.2023.34.e28
Objective Lower extremity lymphedema (LEL) is a well-known adverse effect related to cervical and endometrial cancer (CEC); however, very few studies have elucidated the clinicopathologic risk factors related to LEL. We... -
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- Alternative splicing of PSMD13 mediated by genetic variants is significantly associated with endometrial cancer risk
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He S, Cao R, Mao Y, Li N, Wang Y, Ma H, Tian K
- KMID: 2552556
- J Gynecol Oncol.
- 2023 May;34(3):e40.
- doi: 10.3802/jgo.2023.34.e40
Objective Accumulating evidence has shown that aberrant alternative splicing events are closely associated with the onset and development of cancer. However, whether genetic variants-associated alternative splicing is linked to risk of... -
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- Preclinical investigation of patient-derived cervical cancer organoids for precision medicine
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Seol HS, Oh JH, Choi E, Kim S, Kim H, Nam EJ
- KMID: 2552559
- J Gynecol Oncol.
- 2023 May;34(3):e35.
- doi: 10.3802/jgo.2023.34.e35
Objective Advanced cervical cancer is still difficult to treat and in the case of recurrent cancer, it is desirable to utilize personalized treatment rather than uniform treatment because the type of... -
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- An update of oncologic and obstetric outcomes after abdominal trachelectomy using the FIGO 2018 staging system for cervical cancer: a single-institution retrospective analysis
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Okugawa K, Yahata H, Ohgami T, Yasunaga M, Asanoma K, Kobayashi H, Kato K
- KMID: 2552560
- J Gynecol Oncol.
- 2023 May;34(3):e41.
- doi: 10.3802/jgo.2023.34.e41
Objective To apply the International Federation of Gynecology and Obstetrics (FIGO) 2018 staging system to all patients who underwent trachelectomy in our previous study and to update the oncologic and obstetric... -
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- Interleukin-34 cancels anti-tumor immunity by PARP inhibitor
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Nakamura T, Kajihara N, Hama N, Kobayashi T, Otsuka R, Han N, Wada H, Hasegawa Y, Suzuki N, Seino Ki
- KMID: 2552561
- J Gynecol Oncol.
- 2023 May;34(3):e25.
- doi: 10.3802/jgo.2023.34.e25
Objective Breast cancer susceptibility gene 1 (BRCA1)-associated ovarian cancer patients have been treated with A poly (ADP-ribose) polymerase (PARP) inhibitor, extending the progression-free survival; however, they finally acquire therapeutic resistance. Interleukin... -
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- Role of systematic lymphadenectomy in patients with intermediate to high-risk early stage endometrial cancer
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Kim NR, So KA, Kim TJ, Lim K, Lee KH, Kim MK
- KMID: 2552553
- J Gynecol Oncol.
- 2023 May;34(3):e23.
- doi: 10.3802/jgo.2023.34.e23
Objective To determine the clinical significance of systematic lymph node dissection (LND) and to better define the relevant extent of LND in intermediate- to high-risk early stage endometrial cancer (EC). Methods Patients who... -
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