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Reducing distal pancreatectomy by posterolateral approach for splenectomy in the surgical management of ovarian cancer

Park SY

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Emergency craniotomy: a life-saving procedure as part of multi-modal therapy of GTN

Ghorani E, Seckl MJ

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Posterior pelvic exenteration, a crucial component in the surgeon’s toolbox for optimizing surgical cytoreduction for advanced ovarian cancer

Moukarzel LA, Chi DS

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Molecular classification of endometrial cancer: entering an era of precision medicine

Goulder A, Gaillard SL

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PARP inhibitors in ovarian cancer: overcoming resistance with combination strategies

Miller RE, El-Shakankery KH, Lee JY

The use of PARP inhibitors (PARPi) in patients with epithelial ovarian cancer is expanding, with the transition from use in recurrent disease to the first-line setting. This is accompanied with...
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Laparoscopic resection surgery for malignant transformation of extragonadal endometriosis by the “pincer” approach

Kanao H, Nishimura M, Murakami A

Up to 1% of women with endometriosis develop endometriosis-associated neoplasms [1]. Most endometriosis-associated malignant tumors develop from the ovarian endometriomas, whereas those developing from extragonadal lesions are extremely rare, estimated...
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Oncologic outcomes according to the level of disease burden in patients with metachronous distant metastases from uterine cervical cancer: a Korean Radiation Oncology Group study (KROG 18-10)

Park S, Park W, Park SH, Kim JY, Kim JH, Kim H, Kim YS, Cho WK, Yoon WS, Yang DS

Objective This study aimed to evaluate the oncologic outcomes according to disease burden in uterine cervical cancer patients with metachronous distant metastases. Methods Between 2005 and 2015, 163 patients with metachronous distant metastases...
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Treatment and outcomes in undifferentiated and dedifferentiated endometrial carcinoma

Hamilton SN, Tinker AV, Kwon J, Lim P, Kong I, Sihra S, Koebel M, Lee CH

Objective Undifferentiated and dedifferentiated endometrial carcinoma is a rare type of uterine malignancy. This study assesses disease characteristics, treatment and survival outcomes in patients with undifferentiated and dedifferentiated endometrial carcinoma treated...
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Posterior pelvic exenteration for ovarian cancer: surgical and oncological outcomes

Houvenaeghel G, Nonneville Ad, Blache G, Buttarelli M, Jauffret C, Mokart D, Sabiani L

Objective Posterior pelvic exenteration (PPE) can be required to achieve complete resection in ovarian cancer (OC) patients with large pelvic disease. This study aimed to analyze morbidity, complete resection rate, and...
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HPV vaccination among seropositive, DNA negative cohorts: a systematic review & meta-analysis

Eochagain CM, Power R, Parker I, Brennan D

Objective Vaccine efficacy among previously exposed, but currently uninfected women, i.e., those who have serological evidence of a prior human papillomavirus (HPV) infection without corresponding detectable HPV DNA, remains incompletely defined....
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Effectiveness of craniotomy and long-term survival in 35 patients with gestational trophoblastic neoplasia with brain metastases: a clinical retrospective analysis

Li Y, Wang W, Wan X, Feng F, He YL, Yang J, Xiang Y

Objective To investigate the clinical characteristics, treatments, and prognostic factors among patients with gestational trophoblastic neoplasia (GTN) exhibiting brain metastases who underwent craniotomy. Methods Thirty-five patients with GTN who had brain metastases and...
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Significance of histology and nodal status on the survival of women with early-stage cervical cancer: validation of the 2018 FIGO cervical cancer staging system

Machida H, Matsuo K, Kobayashi Y, Momomura M, Takahashi F, Tabata T, Kondo E, Yamagami W, Ebina Y, Kaneuchi M, Nagase S, Mikami M

Objective To assess the efficacy of the FIGO 2018 classification system for nodal-specific classifications for early-stage cervical cancer; specifically, to examine the impact of nodal metastasis on survival and the effect...
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Predictors of postoperative pancreatic fistula after splenectomy with or without distal pancreatectomy performed as a component of cytoreductive surgery for advanced ovarian cancer

Nishikimi K, Tate S, Matsuoka A, Otsuka S, Shozu M

Objective Splenectomy with or without distal pancreatectomy is occasionally performed during cytoreductive surgery for advanced ovarian cancer. We investigated pre-, intra-, postoperative risk factors and predictors of clinically relevant postoperative pancreatic...
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Genomic landscape of advanced endometrial cancer analyzed by targeted next-generation sequencing and the cancer genome atlas (TCGA) dataset

Hong JH, Cho HW, Ouh YT, Lee JK, Chun Y, Gim JA

Objective Recent studies have detailed the genomic landscape of endometrial cancer (EC); however, no study has focused on genetic alterations in advanced EC. We performed genomic profiling of patients with advanced...
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Clinicopathological and molecular characterization of high-grade endometrial carcinoma with POLE mutation: a single center study

Yu S, Sun Z, Zong L, Yan J, Yu M, Chen J, Lu Z

Objective The molecular classification system of endometrial carcinoma (EC) in ‘The Cancer Genome Atlas’ is widely acknowledged for its prognostic utility. Subsequently, more simplified classification system that incorporate DNA polymerase epsilon...
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Clinicopathologic and protein markers distinguishing the “polymerase epsilon exonuclease” from the “copy number low” subtype of endometrial cancer

Kim K, Hwangbo S, Kim H, Kim YB, No JH, Suh DHx, Park T

Objective The need to perform genetic sequencing to diagnose the polymerase epsilon exonuclease (POLE) subtype of endometrial cancer (EC) hinders the adoption of molecular classification. We investigated clinicopathologic and protein markers...
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Prognostic value of complete metabolic response on 18F-FDG-PET/CT after three cycles of neoadjuvant chemotherapy in advanced high-grade serous ovarian cancer

Chung YS, Kim Y, Kim HS, Lee JY, Kang WJ, Kim S, Kim SW

Objective We investigated the prognostic value of complete metabolic response (CMR) on 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) after 3 cycles of neoadjuvant chemotherapy (NAC) in advanced high-grade serous ovarian cancer...
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