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Early-stage epithelial ovarian cancer: is systematic lymph node staging mandatory?

Imterat M, Harter P

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Should adjuvant chemotherapy be formally studied among patients found to have pelvic lymph node metastases following radical hysterectomy with lymphadenectomy for early-stage cervical cancer?

Bujnak AC, Tewari KS

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Report from the 36th Annual Meeting of the Korean Society of Gynecologic Oncology (KSGO)

Kim JH, Noh JJ, Eoh KJ, Kim YT

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Towards the elimination of cervical cancer in Japan

Hanley SJ

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Major clinical research advances in gynecologic cancer in 2020

Lee YY, Choi MC, Park JY, Suh DH, Kim JW

In 2020 series, we summarized the major clinical research advances in gynecologic oncology with providing representative figures of the most influential study for 1 of each 3 gynecologic cancers: cervix,...
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How to perform sentinel node detection in high-risk endometrial cancer: one step forward

Balaya V, Lecuru F, Laas E

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Relevance of pathologic features in risk stratification for early-stage endometrial cancer

Guerra E, Matias-Guiu X

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Vaginal cancer as a late complication of radiotherapy for endometrial cancer and ileo-perineal fistula after total pelvic exenteration

Comba C, Topaktas M, Bozkurt H, Erbin A, Ozdogan B, Demir O

Pelvic exenteration is a highly morbid operation and remains one of the most catastrophic surgical procedures in gynecological oncology. We would like to present the case of total pelvic exenteration...
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A phase II, open-labeled, single-arm study of dose-dense paclitaxel plus carboplatin in advanced or recurrent uterine endometrial cancer treatment: a KCOG-G1303, DOENCA trial

Hori K, Nishio S, Ushijima K, Kasamatsu Y, Kondo E, Takehara K, Ito K

Objective To determine the safety and efficacy of dose-dense (dd) paclitaxel (PTX) and carboplatin (CBDCA) in treating advanced or recurrent endometrial cancer. Methods Women aged 20–75 years with histologically confirmed endometrial cancer, the...
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Sentinel lymph Node mapping versus systematic pelvic lymphadenectomy on the prognosis for patients with intermediate-high-risk Endometrial Cancer confined to the uterus before surgery: trial protocol for a non-inferiority randomized controlled trial (SNEC trial)

Guan J, Xue Y, Zang Ry, Liu Jh, Zhu Jq, Zheng Y, Wang B, Wang Hy, Chen Xj

Background Sentinel lymph node (SLN) mapping has been recommended as an alternative staging approach to lymphadenectomy for apparent uterine-confined endometrial cancer (EC). However, the prognostic value of SLN mapping alone instead...
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Impact of metformin on survival outcome in ovarian cancer: a nationwide population-based cohort study

Park JY, Lim MC, Baek MH, Park YH, Kim S

Objective Investigation of new drugs (INDs) is a tremendously inefficient process in terms of time and cost. Drug repositioning is another method used to investigate potential new agents in well-known drugs....
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Concordance between preoperative ESMO-ESGO-ESTRO risk classification and final histology in early-stage endometrial cancer

Daix M, Angeles MA, Migliorelli F, Kakkos A, Gomez CM, Delbecque K, Mery E, Tock S, Gabiache E, Decuypere M, Goffin F, Martinez A, Ferron G, Kridelka F

Objective To evaluate the concordance between preoperative European Society for Medical Oncology (ESMO)-European Society of Gynaecological Oncology (ESGO)-European SocieTy for Radiotherapy and Oncology (ESTRO) risk classification in early-stage endometrial cancer (EC)...
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Autologous cervical tumor lysate pulsed dendritic cell stimulation followed by cisplatin treatment abrogates FOXP3+ cells in vitro

Dhandapani H, Seetharaman A, Jayakumar H, Ganeshrajah S, Singh SS, Thangarajan R, Ramanathan P

Objective Dendritic cells (DCs) are administered as immunotherapeutic adjuvants after the completion of standard treatment in most settings. However, our Phase I trial indicated that one patient out of four, who...
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Mapping the robotic hysterectomy learning curve and re-establishing surgical training metrics

Turner TB, Kim KH

Objective Common robotic training curricula in the US entail completion of an online module followed by lab training with standardized exercises, such as manipulating needles with robotic needle drivers. Assessments are...
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Characteristics of progestin-insensitive early stage endometrial cancer and atypical hyperplasia patients receiving second-line fertility-sparing treatment

Zhou S, Xu Z, Yang B, Guan J, Shan W, Shi Y, Chen X

Objective This study investigated the characteristics of progestin-insensitive endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH) patients receiving fertility-sparing treatments and assessed the therapeutic effects of second-line fertility-preserving treatments. Methods Three hundred...
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Paraaortic sentinel lymph node detection in intermediate and high-risk endometrial cancer by transvaginal ultrasound-guided myometrial injection of radiotracer (TUMIR)

Angeles MA, Migliorelli F, Vidal-Sicart S, Saco A, Ordi J, Ros C, Fusté P, Munmany M, Escura S, Carreras N, Sánchez-Izquierdo N, Pahisa J, Torné A, Paredes P, Pino Md

Objective We aimed to evaluate the accuracy of sentinel lymph node (SLN) mapping with transvaginal ultrasound-guided myometrial injection of radiotracer (TUMIR) to detect lymph node (LN) metastases, in patients with intermediate...
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