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The role of secondary cytoreduction in recurrent, platinum-sensitive ovarian cancer: what do the trials tell us?

Coleman RL

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The current status of laparoscopic and robotic para-aortic lymphadenectomy in gynecologic cancer surgery

Ind T

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Why was GOG-0213 a negative trial?

Ehmann S, Zivanovic O, Chi DS

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The systemic immune-inflammation index (SII) is an independent prognostic parameter of survival in patients with invasive vulvar cancer

Bartl T, Bekos C, Postl M, Alexander R, Polterauer S, Stefanie A, Richard S

Objective: To assess the prognostic value of the systemic immune-inflammation index (SII) in patients with vulvar cancer. Methods: Data of 130 consecutive patients who underwent primary surgical resection for vulvar cancer...
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The extent of aortic lymphadenectomy in locally advanced cervical cancer impacts on survival

Llueca A, Escrig J, Gil-Moreno A, Benito V, Hernández A, Díaz-Feijoo B, on behalf of Spain-Gynecologic Oncology Group (GOG) Working Group

Objective: The prognostic impact of surgical paraaortic staging remains unclear in patients with locally advanced cervical cancer (LACC). The objective of our study was to evaluate the results of the...
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Time for enhancing government-led primary prevention of cervical cancer

Min KJ, Suh DH, Baba T, Chen X, Kim JW, Kobayashi Y, Kwon J, Lim MC, Lee JY, Nagase S, Park JY, Tangjitgamol S, Watari H

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Total laparoscopic vs. conventional open abdominal nerve-sparing radical hysterectomy: clinical, surgical, oncological and functional outcomes in 301 patients with cervical cancer

Ceccaroni M, Roviglione G, Malzoni M, Cosentino F, Spagnolo E, Clarizia R, Casadio P, Seracchioli R, Ghezzi F, Mautone D, Bruni F, Uccella S

Objective: Total laparoscopic nerve-sparing radical hysterectomy (TL-NSRH) has been considered a promising approach, however, surgical, clinical, oncological and functional outcomes have not been systematically addressed. We present a large retrospective...
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Randomized phase III trial comparing pegylated liposomal doxorubicin (PLD) at 50 mg/m2 versus 40 mg/m2 in patients with platinum-refractory and -resistant ovarian carcinoma: the JGOG 3018 Trial

Motohashi T, Yabuno A, Michimae H, Ohishi T, Nonaka M, Takano M, Nishio S, Fujiwara H, Keiichi K, Kondo E, Sugiyama T, Tabata T

Objective: The standard dose for pegylated liposomal doxorubicin (PLD) is 50 mg/m2 every 4 weeks. While 40 mg/m2 has recently been used in clinical practice, evidence supporting this use remains...
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A new technique of laparoscopic para-aortic lymphadenectomy optimizes perioperative outcome

Lin Y, He L, Mei Y

Objective: The aim of the present study was to introduce a new technique for laparoscopic para-aortic lymphadenectomy (PAL): an invented retroperitoneum suspension needle combined with modified trocar placement. Methods: This prospective...
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Tailored-dose chemotherapy with gemcitabine and irinotecan in patients with platinum-refractory/resistant ovarian or primary peritoneal cancer: a phase II trial

Tate S, Nishikimi K, Matsuoka A, Otsuka S, Kato K, Takahashi Y, Shozu M

Objective: We investigated the efficacy and toxicity of tailored-dose chemotherapy with gemcitabine and irinotecan for platinum-refractory/resistant ovarian or primary peritoneal cancer. Methods: We enrolled patients with ovarian or primary peritoneal cancer...
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Robot-assisted extraperitoneal paraaortic lymphadenectomy (RAePAL) performed with the bipolar cutting method

Yanai S, Kanno K, Aiko K, Ando M

Objective: In comparison with laparoscopic transperitoneal para-aortic lymphadenectomy, the advantages of laparoscopic extraperitoneal para-aortic lymphadenectomy (ePAL) are that the operative field is not obstructed by bowel and the Trendelenburg position...
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Cancer field surgery in endometrial cancer: peritoneal mesometrial resection and targeted compartmental lymphadenectomy for locoregional control

Buderath P, Rusch P, Mach P, Kimmig R

Objective: Peritoneal mesometrial resection (PMMR) plus targeted compartmental lymphadenectomy (TCL) aims at removal of the locoregional cancer field in endometrial cancer (EC). Optimal locoregional control without adjuvant radiotherapy and acceptable...
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Conditional relative survival of cervical cancer: a Korean National Cancer Registry Study

Shin DW, Bae J, Ha J, Jung KW

Objective: Conditional relative survival (CRS) considers changes in prognosis over time and may offer more useful estimates for survivors. We aimed to investigate CRS among patients with cervical cancer stratified...
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Trend analysis of process quality indicators for the Korean National Cervical Cancer Screening Program from 2005 to 2013

Bui CN, Choi E, Suh M, Jun JK, Jung KW, Lim MC, Choi KS

Objective: This study sought to examine changes in trends for quality indicators of the population-based Korean National Cancer Screening Program (KNCSP) for cervical cancer from years 2005 to 2013. Methods: Our...
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Suppression of ARID1A associated with decreased CD8 T cells improves cell survival of ovarian clear cell carcinoma

Jung US, Min KW, Kim DH, Kwon MJ, Park H, Jang HS

Objective: AT-rich interactive domain 1A (ARID1A) plays an important role as a tumor suppressor gene in ovarian clear cell carcinoma (OCCC), but the clinical application of ARID1A remains unclear. The...
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