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Neuroprotective Therapy in Parkinson's Disease: Current Status and New Directions from Experimental and Genetic Clues

Lin W, Kang UJ

Despite successful treatment of Parkinson's disease (PD) with a wide variety of symptomatic therapy, the disease continues to progress and drug-resistance symptoms become the predominant factors producing the disability of...
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Primary Medullary Hemorrhage Associated with Hypertension

Kwon HM, Park JM, Lee JY, Yoon BW

Spontaneous primary medullary hemorrhage is a rare event. A 64-year-old man was admitted for sudden-onset vertigo and vomiting. His clinical features were similar to those of lateral medullary syndrome. The...
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Endogenous Zinc in Neurological Diseases

Koh JY

The use of zinc in medicinal skin cream was mentioned in Egyptian papyri from 2000 BC (for example, the Smith Papyrus), and zinc has apparently been used fairly steadily throughout...
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Safety and Feasibility of Subcutaneous Low Molecular Weight Heparin for Cerebral Venous Sinus Thrombosis

Kim JS, Jeong SH, Kim DH, Kim J

BACKGROUND AND PURPOSE: The effect of low molecular weight heparin (LMWH) in the management of cerebral venous thrombosis (CVT) remains unclear. The present study was performed to determine the safety...
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Cortical Laminar Necrosis associated with Osmotic Demyelination Syndrome

Cho AH, Choi CG, Lee SA

Cortical laminar necrosis has been rarely observed in osmotic demyelination syndrome. We report a 32-year-old female patient who became comatose after the rapid correction of hyponatremia. There were high signal...
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Plasma Fibrinolysis Inhibitor Levels in Acute Stroke Patients with Thrombolysis Failure

Kim SH, Han SW, Kim EH, Kim DJ, Lee KY, Kim DI, Heo JH

BACKGROUND AND PURPOSE: Thrombolytics-induced recanalization fails in a significant portion of patients with ischemic stroke, which is partly due to the resistance of clots to lysis by thrombolytic agents. The...
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Clinical Analysis of Blepharospasm and Apraxia of Eyelid Opening in Patients with Parkinsonism

Yoon WT, Chung EJ, Lee SH, Kim BJ, Lee WY

BACKGROUND AND PURPOSE: Blepharospasm (BSP) and apraxia of eyelid opening (AEO) have been reported as dystonia related with parkinsonism. However, systematic analysis of clinical characteristics of BSP and AEO in...
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The Closing-in Phenomenon in Alzheimer's Disease and Vascular Dementia

Chin J, Lee BH, Seo SW, Kim EJ, Suh MK, Kang SJ, Na DL

BACKGROUND AND PURPOSE: The closing-in phenomenon is the tendency to draw near or on the target when copying figures, which has been found mostly in patients with Alzheimer's disease (AD)....
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Predicting the Long-Term Outcome after Subacute Stroke within the Middle Cerebral Artery Territory

Bang OY, Park HY, Yoon JH, Yeo SH, Kim JW, Lee MA, Park MH, Lee PH, Joo IS, Huh K

BACKGROUND AND PURPOSE: The National Institutes of Health Stroke Scale (NIHSS) score is known to be effective in predicting the likelihood of recovery after stroke. However, the baseline NIHSS score...
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