- Targeting Epigenetic ‘Readers’ with Natural Compounds for Cancer Interception
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Damiani E, Duran MN, Mohan N, Rajendran P, Dashwood RH
- KMID: 2510147
- J Cancer Prev.
- 2020 Dec;25(4):189-203.
- doi: 10.15430/JCP.2020.25.4.189
Natural compounds from diverse sources, including botanicals and commonly consumed foods and beverages, exert beneficial health effects via mechanisms that impact the epigenome and gene expression during disease pathogenesis. By... -
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- Recent Advances in the Development of TGF-β Signaling Inhibitors for Anticancer Therapy
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Lee HJ
- KMID: 2510150
- J Cancer Prev.
- 2020 Dec;25(4):213-222.
- doi: 10.15430/JCP.2020.25.4.213
TGF-β is a multifunctional cytokine that plays an important role in both physiologic and pathologic processes, including cancer. Importantly, TGF-β has a dual role in tumorigenesis, acting as a tumor... -
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- Astaxanthin Inhibits Helicobacter pylori-induced Inflammatory and Oncogenic Responses in Gastric Mucosal Tissues of Mice
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Han H, Lim JW, Kim H
- KMID: 2510155
- J Cancer Prev.
- 2020 Dec;25(4):244-251.
- doi: 10.15430/JCP.2020.25.4.244
Helicobacter pylori is recognized as a risk factor for gastric carcinogenesis. The chronic exposure of gastric epithelium to H. pylori induces a prolonged inflammatory state that may progress to gastric... -
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- Colon Cancer Risk of a Westernized Diet Is Reduced in Mice by Feeding Cruciferous or Apiaceous Vegetables at a Lower Dose of Carcinogen but Not a Higher Dose
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Kim S, Abernathy BE, Trudo SP, Gallaher DD
- KMID: 2510152
- J Cancer Prev.
- 2020 Dec;25(4):223-233.
- doi: 10.15430/JCP.2020.25.4.223
Western-style diets (WD) are associated with greater risk of colon cancer. Exposure to 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP), a food-borne carcinogen, is linked to increased colon cancer risk. In contrast, intake of... -
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- Interaction between Peptidyl-prolyl Cis-trans Isomerase NIMA-interacting 1 and GTP-H-Ras: Implications for Aggressiveness of Human Mammary Epithelial Cells and Drug Resistance
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Saeidi S, Joo S, Kim SJ, Jagadeesh ASV, Surh YJ
- KMID: 2510153
- J Cancer Prev.
- 2020 Dec;25(4):234-243.
- doi: 10.15430/JCP.2020.25.4.234
Aberrant activation of Ras has been implicated in aggressiveness of breast cancer. Among Ras isoforms (H-, K-, and N-), H-Ras has been known to be primarily responsible for invasion and... -
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- Sry-related High Mobility Group Box 17 Functions as a Tumor Suppressor by Antagonizing the Wingless-related Integration Site Pathway
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Anani M, Nobuhisa I, Taga T
- KMID: 2510148
- J Cancer Prev.
- 2020 Dec;25(4):204-212.
- doi: 10.15430/JCP.2020.25.4.204
A transcription factor Sry-related high mobility group box (Sox) 17 is involved in developmental processes including spermatogenesis, cardiovascular system, endoderm formation, and so on. In this article, we firstly review... -
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- Imatinib and GNF-5 Exhibit an Inhibitory Effect on Growth of Hepatocellar Carcinoma Cells by Downregulating S-phase Kinase-associated Protein 2
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Zhang H, Yi J, Yoon D, Ryoo Z, Lee I, Kim M
- KMID: 2510156
- J Cancer Prev.
- 2020 Dec;25(4):252-257.
- doi: 10.15430/JCP.2020.25.4.252
Hepatocellular carcinoma (HCC) is the most common primary liver cancer and is one of the leading causes of cancer-related deaths worldwide. Imatinib and GNF-5 are breakpoint cluster region-Abelson murine leukemia... -
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